ChemicalBook > CAS DataBase List > Z-DQMD-FMK

Z-DQMD-FMK

Product Name
Z-DQMD-FMK
CAS No.
767287-99-0
Chemical Name
Z-DQMD-FMK
Synonyms
Z-DQMD-FMK;Z-D(OME)QMD(OME)-FMK;CASPASE-3 INHIBITOR V;Z-ASP(OME)-GLN-MET-ASP(OME)-FMK;Z-D(OME)QMD(OME) (FLUOROMETHYLKETONE);Z-DQMD-FMK, Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK;Z-ASP(OME)-GLN-MET-ASP(OME)-FLUOROMETHYLKETONE;Z-ASP(OME)-GLN-MET-DL-ASP(OME)-FLUOROMETHYLKETONE;BENZYLOXYCARBONYL-ASP(OME)-GLN-MET-ASP(OME)-FLUOROMETHYLKETONE;L-Methioninamide, N-[(phenylmethoxy)carbonyl]-L-α-aspartyl-L-glutaminyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, methyl ester
CBNumber
CB1226063
Molecular Formula
C29H40FN5O11S
Formula Weight
685.72
MOL File
Mol file
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Z-DQMD-FMK Property

storage temp. 
−20°C
solubility 
≥29.2 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form 
powder
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology
Product number
A1921
Product name
Z-DQMD-FMK
Packaging
1unit
Price
$28
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA111096
Product name
Z-Asp(OMe)-Gln-Met-DL-Asp(OMe)-fluoromethylketone
Packaging
250ug
Price
$110
Updated
2021/12/16
ApexBio Technology
Product number
A1921
Product name
Z-DQMD-FMK
Packaging
5mg
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA111096
Product name
Z-Asp(OMe)-Gln-Met-DL-Asp(OMe)-fluoromethylketone
Packaging
500ug
Price
$190
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA111096
Product name
Z-Asp(OMe)-Gln-Met-DL-Asp(OMe)-fluoromethylketone
Packaging
1mg
Price
$328
Updated
2021/12/16
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Z-DQMD-FMK Chemical Properties,Usage,Production

Uses

Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK is an inhibitor for caspase-3, and inhibits Dihydroartemisinin (HY-N0176) and Dictamnine (HY-N0849) co-induced apoptosis[1].

Biological Activity

Caspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro .

References

1. susan s. chou*, michael s. clegg, alterations in protein kinase c activity and processing during zinc-deficiency-induced cell death, biochem. j. (2004) 383, 63–71 2. j. h. banga, e. s. han. differential response of mg132 cytotoxicity against small cell lung cancer cells to changes in cellular gsh contents. biochemical pharmacology 68 (2004) 659–666. 3. t. shimohata, h. zhao, εpkc may contribute to the protective effect of hypothermia in a rat focal cerebral ischemia model. stroke. 2007;38:375-380

Z-DQMD-FMK Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-DQMD-FMK Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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767287-99-0, Z-DQMD-FMKRelated Search:


  • Z-DQMD-FMK, Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK
  • Z-D(OME)QMD(OME) (FLUOROMETHYLKETONE)
  • Z-D(OME)QMD(OME)-FMK
  • Z-DQMD-FMK
  • Z-ASP(OME)-GLN-MET-ASP(OME)-FLUOROMETHYLKETONE
  • Z-ASP(OME)-GLN-MET-ASP(OME)-FMK
  • Z-ASP(OME)-GLN-MET-DL-ASP(OME)-FLUOROMETHYLKETONE
  • CASPASE-3 INHIBITOR V
  • BENZYLOXYCARBONYL-ASP(OME)-GLN-MET-ASP(OME)-FLUOROMETHYLKETONE
  • L-Methioninamide, N-[(phenylmethoxy)carbonyl]-L-α-aspartyl-L-glutaminyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, methyl ester
  • 767287-99-0
  • C29H40FN5O11S
  • Caspases/Apoptosis
  • Caspase/Related products
  • Apoptosis