QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER

Product Name: QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER
CAS No.: 1247-97-8
Chemical Name: QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER
Synonyms: PENTAMETHYLQUERCETIN;Pentamethoxyquercetin;QUERCETIN-3,5,7,3',4';QUERCETINPENTAMETHYLETHER;Rutoside Trihydrate Impurity 5;3,3',4',5,7-Pentamethoxyflavone;3,5,7,3',4'-PENTAMETHOXYFLAVONE;QUERCETIN-3,7-DIMETHYLETHER(RG);Quercetin-3,5,7,3',4'-pentamethylether;QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER
CBNumber: CB1226629
Molecular Formula: C20H20O7
Formula Weight: 372.37
MOL File: 1247-97-8.mol

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QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER Property

Melting point:: 152-156°C
Boiling point:: 561.9±50.0 °C(Predicted)
Density: 1.29±0.1 g/cm3(Predicted)
form: Solid
color: White to light brown
LogP: 2.370 (est)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0135217
Product name: 3,5,7,3′,4′-Pentamethoxyflavone
Packaging: 5mg
Price: $180
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0032041
Product name: QUERCETIN-3,5,7,3',4'-PENTAMETHYLETHER
Purity: 95.00%
Packaging: 10MG
Price: $771.31
Updated: 2021/12/16

Arctom

Product number: CFN70262
Product name: Quercetin3,5,7,3,4-pentamethylether
Purity: ≥98%
Packaging: 10mg
Price: $318
Updated: 2021/12/16

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QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER Chemical Properties,Usage,Production

Uses

3,5,7,3’,4’-Pentamethoxyflavone is a Ca2+ channel inhibitor. 3,5,7,3’,4’-Pentamethoxyflavone can protect DNA from oxidative damage. 3,5,7,3’,4’-Pentamethoxyflavone can induce relaxation of the human corpus cavernosum through calcium mobilization-related mechanisms. 3,5,7,3’,4’-Pentamethoxyflavone can promote the expression of eNOS and cystathionine gamma lyase CSE proteins in middle-aged male rats and regulate vascular function. 3,5,7,3’,4’-Pentamethoxyflavone can be used in research related to diabetes and cardiovascular diseases[1][2][4].

in vivo

3,5,7,3’,4’-Pentamethoxyflavone (22 mg/kg; twice daily; 6 weeks; p.o.) can promote the expression of eNOS and CSE proteins in middle-aged male rats, and regulate vascular function by antagonizing the contraction of phenylephrine and enhancing the vasodilation of acetylcholine^[4].

Animal Model:	Middle-aged (12–14 month old) Wistar male rats^[4].
Dosage:	22 mg/kg
Administration:	Oral gavage (p.o.); twice daily; 6 weeks
Result:	Caused a decrease in plasma glucose and an increase in plasma HDL cholesterol levels of the rats.

References

[1] Jakhar R, et al. 3,5,7,3',4'-pentamethoxyflavone, a quercetin derivative protects DNA from oxidative challenges: potential mechanism of action. J Photochem Photobiol B. 2014 Feb 5;131:96-103. DOI:10.1016/j.jphotobiol.2014.01.003
[2] Jansakul C, et al. Relaxant mechanisms of 3, 5, 7, 3', 4'-pentamethoxyflavone on isolated human cavernosum. Eur J Pharmacol. 2012 Sep 15;691(1-3):235-44. DOI:10.1016/j.ejphar.2012.07.019
[3] Mayangsari Y, et al. 3,5,7,3',4'-Pentamethoxyflavone Enhances the Barrier Function through Transcriptional Regulation of the Tight Junction in Human Intestinal Caco-2 Cells. J Agric Food Chem. 2021 Sep 8;69(35):10174-10183. DOI:10.1021/acs.jafc.1c04295
[4] Yorsin S, et al. Increased vascular eNOS and cystathionine-γ-lyase protein after 6 weeks oral administration of 3, 5, 7, 3', 4'-pentamethoxyflavone to middle-aged male rats. Naunyn Schmiedebergs Arch Pharmacol. 2016 Nov;389(11):1183-1194. DOI:10.1007/s00210-016-1280-0

QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER Preparation Products And Raw materials

Raw materials

Preparation Products

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QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER Suppliers

China 69 Czech 1 Germany 2 Japan 1 United Kingdom 3 United States 8 USA 1 Global 85

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-021-61259138 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
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Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
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Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
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Email: tauto@tautobiotech.com
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Finetech Industry Limited

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Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
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Wuhan ChemFaces Biochemical Co., Ltd.

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Email: aileen@chemfaces.com
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Biyu Biotechnology (Shanghai) Co., ltd

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Shanghai Haozhixiang Biotechnology Co., Ltd

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Shanghai YuanYe Biotechnology Co., Ltd.

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Shanghai SuperLan Chemcial Technique Centre

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Beijing Jin Ming Biotechnology Co., Ltd.

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View Lastest Price from QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3,3',4',5,7-Pentamethoxyflavone 1247-97-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000Kg
Release date: 2024-08-08

Career Henan Chemical Co

Product: Quercetin-3,5,7,3',4'-pentamethylether 1247-97-8
Price: US $9.80/KG
Min. Order: 1g
Purity: ＞98%
Supply Ability: 20 tons
Release date: 2020-02-10

1247-97-8, QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHERRelated Search:

3',4',5,7-TETRAMETHOXYFLAVONE Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) PONCIRIN 4',5-DIHYDROXY-7-METHOXYFLAVONE Naringenin GARDENIN B MOSLOFLAVONE MEDICAGOL Quercetin-7-O-β-D-glucopyranoside QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER 3,3',4',5,6,7,8-heptamethoxyflavone QUERCETINPENTAACETATE HEPTAMETHOXYFLAVONE 3-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, tetrakis(2-hydroxyethyl) ether RARECHEM BW GA 0418 RARECHEM BW GA 0417 RARECHEM BW GA 0416 penta-O-ethylquercetin

Pentamethoxyquercetin

QUERCETINPENTAMETHYLETHER

PENTAMETHYLQUERCETIN

2-(3,4-Dimethoxyphenyl)-3,5,7-trimethoxy-4H-1-benzopyran-4-one

3,3',4',5,7-Pentamethoxyflavone

Quercetin 3,3',4',5,7-pentamethyl ether

3,5,7,3',4'-PENTAMETHOXYFLAVONE

QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER

QUERCETIN-3,5,7,3',4'

2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxy-chromen-4-one

2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxychromen-4-one

2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxy-chromone

QUERCETIN-3,7-DIMETHYLETHER(RG)

4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxy-

Rutoside Trihydrate Impurity 5

2-(3,4-dimethoxyphenyl)-3,5,7-trimethoxy-4H-chromen-4-one

disorders,3,5,7,3′,4′Pentamethoxyflavone,polymethoxyflavonoid,3,5,7,3′,4′ Pentamethoxyflavone,obesity,3,5,7,3′,4′-Pentamethoxyflavone,adiponectin,adipogenesis,anti-metabolic,Inhibitor,inhibit

Quercetin-3,5,7,3',4'-pentamethylether

3,5,7,3′,4′-Pentamethoxyflavone, 10 mM in DMSO

1247-97-8