ChemicalBook > CAS DataBase List > QUERCETINPENTAACETATE

QUERCETINPENTAACETATE

Product Name
QUERCETINPENTAACETATE
CAS No.
1064-06-8
Chemical Name
QUERCETINPENTAACETATE
Synonyms
Quercetin acetate;Pentaacetylquercetin;Quercetine pentaacetate;3,3',4',5,7-Pentaacetoxyflavone;3,3',4',5,7-Penta(acetyloxy)flavone;Quercetin pentaacetate, 10 mM in DMSO;3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one;2-(3,4-diacetoxyphenyl)-4-oxo-4H-chromene-3,5,7-triyl triacetate;[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate;Quercetin pentaacetate,Respiratory syncytial virus,inhibit,Inhibitor,RSV
CBNumber
CB91405559
Molecular Formula
C25H20O12
Formula Weight
512.42
MOL File
1064-06-8.mol
More
Less

QUERCETINPENTAACETATE Property

Melting point:
193 °C
Boiling point:
666.4±55.0 °C(Predicted)
Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Dichloromethane, Ethyl Acetate
form 
Solid
color 
Beige
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
26694
Product name
Pentaacetylquercetin
Packaging
10mg
Price
$48
Updated
2024/03/01
Cayman Chemical
Product number
26694
Product name
Pentaacetylquercetin
Packaging
500mg
Price
$1153
Updated
2024/03/01
Cayman Chemical
Product number
26694
Product name
Pentaacetylquercetin
Packaging
50mg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
26694
Product name
Pentaacetylquercetin
Packaging
100mg
Price
$255
Updated
2024/03/01
TRC
Product number
D454465
Product name
[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl]Acetate
Packaging
100mg
Price
$250
Updated
2021/12/16
More
Less

QUERCETINPENTAACETATE Chemical Properties,Usage,Production

Description

Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in vitro (IC50 = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC50 = 20.2 μg/ml). Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC50 = 8.7 μM) and PGE2 production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM. It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC50s = 38, 25, and 58 μM, respectively).

Uses

[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

References

[1] HUI-FANG CHANG L L Y. Radical-scavenging and rat liver mitochondria lipid peroxidative inhibitory effects of natural flavonoids from traditional medicinal herbs[C]//6 1. 2012. DOI: 10.5897/jmpr11.588
[2] YEN-CHOU CHEN. Inhibition of nitric oxide synthase inhibitors and lipopolysaccharide induced inducible NOS and cyclooxygenase-2 gene expressions by rutin, quercetin, and quercetin pentaacetate in RAW 264.7 macrophages[J]. Journal of cellular biochemistry, 2001, 82 4: 537-548. DOI: 10.1002/jcb.1184
[3] JESúS G DíAZ. Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana.[J]. Planta medica, 2008: 171-174. DOI: 10.1055/s-2008-1034278

QUERCETINPENTAACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

QUERCETINPENTAACETATE Suppliers

Canada 1 China 24 Finland 1 India 1 South Korea 1 United States 4 Global 32
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Beijing Stronger Science Co., Ltd.
Tel
0531-88924771 15614660963
Email
elsa.hang@strongerscience.com
Country
China
ProdList
10623
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12000
Advantage
58

1064-06-8, QUERCETINPENTAACETATERelated Search:

7-METHOXYFLAVONOL Isorhamnetin 4-ACETOXY-3-METHOXYCINNAMALDEHYDE ARTEMISININ 2'-HYDROXY-4,4',6'-TRIMETHOXYCHALCONE 3',4',7-TRIMETHOXYFLAVONE QUERCETIN-3,7,3',4'-TETRAMETHYL ETHER 2',4-DIHYDROXY-4',6'-DIMETHOXYCHALCONE 2,4,6-Trimethoxybenzaldehyde QUERCETIN-3,5,7,3',4'-PENTAMETHYL ETHER 3',4',5,7-TETRAMETHOXYFLAVONE 3,4-Diethoxybenzyl alcohol 3,4'-DIMETHOXY-3',5,7-TRIHYDROXYFLAVONE 5,7-DIMETHOXYFLAVONE KAEMPFEROL-3,7,4'-TRIMETHYL ETHER FLAVONE 7-HYDROXY-5-METHOXY-2-PHENYL-CHROMEN-4-ONE 5,7-DIHYDROXY-3-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE

  • 3,3',4',5,7-Penta(acetyloxy)flavone
  • 3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one
  • Pentaacetylquercetin
  • 3,3',4',5,7-Pentaacetoxyflavone
  • Quercetin acetate
  • Quercetine pentaacetate
  • [5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate
  • 4H-1-Benzopyran-4-one, 3,5,7-tris(acetyloxy)-2-[3,4-bis(acetyloxy)phenyl]-
  • Quercetin pentaacetate,Respiratory syncytial virus,inhibit,Inhibitor,RSV
  • 2-(3,4-diacetoxyphenyl)-4-oxo-4H-chromene-3,5,7-triyl triacetate
  • Quercetin pentaacetate, 10 mM in DMSO
  • 1064-06-8