ARTEMISININ

Product Name: ARTEMISININ
CAS No.: 491-54-3
Chemical Name: ARTEMISININ
Synonyms: KAEMPFERIDE;ARTEANNUIN;ARTEMISIA ANNUA;kaempferid;ARTEANUIN;QINGHAOSA;Kaemperide;ARTEMISINE;Kempferide;CaMpheride
CBNumber: CB0387974
Molecular Formula: C16H12O6
Formula Weight: 300.26
MOL File: 491-54-3.mol

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ARTEMISININ Property

Melting point:: 156-157 °C(lit.)
Boiling point:: 543.8±50.0 °C(Predicted)
Density: 1.538
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: Chloroform (Slightly, Heated), DMSO (Slightly, Heated), Methanol (Slightly, Heat
pka: 6.32±0.40(Predicted)
color: Yellow
BRN: 305378
LogP: 2.740 (est)
CAS DataBase Reference: 491-54-3

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Safety

Safety Statements: 24/25
WGK Germany: 2
RTECS: KD4170000
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 69545
Product name: Kaempferide
Purity: analytical standard
Packaging: 10mg
Price: $548
Updated: 2024/03/01

TCI Chemical

Product number: K0057
Product name: Kaempferide
Purity: >96.0%(GC)
Packaging: 10mg
Price: $129
Updated: 2024/03/01

TCI Chemical

Product number: K0057
Product name: Kaempferide
Purity: >96.0%(GC)
Packaging: 50mg
Price: $385
Updated: 2024/03/01

Cayman Chemical

Product number: 29673
Product name: Kaempferide
Packaging: 5mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 29673
Product name: Kaempferide
Packaging: 10mg
Price: $121
Updated: 2024/03/01

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ARTEMISININ Chemical Properties,Usage,Production

Chemical Properties

Yellow powder

Uses

Kaempferide is a flavonoid that maintains anti-radical and anti-oxidant capabilities, as well as anti-tumour possibilities. Impurity of Icaritin (I163700).

Definition

ChEBI: A monomethoxyflavone that is the 4'-O-methyl derivative of kaempferol.

Biological Activity

the effects of phytoestrogens have been studied in the hypothalamic-pituitary-gonadal axis and various non-gonadal targets. epidemiologic and experimental evidence indicates a protective effect of phytoestrogens also in colorectal cancer. the mechanism through which estrogenic molecules control colorectal cancer tumorigenesis could possibly involve estrogen receptor β, which is the predominantly expressed estrogen receptor subtype in colon mucosa.

in vitro

kaempferide triglycoside proved to inhibit the proliferation of native and estrogen receptor β overexpressing colon cancer cells via a mechanism not mediated by ligand binding dependent estrogen receptor activation. it affected hct8 cell cycle progression through increasing the g0/g1 cell fraction and in estrogen receptor β overexpressing cells increased two antioxidant enzymes [1].

in vivo

the aim of one previous study was to evaluate the effect of kaempferol on tissue lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal cancer in male wistar rats and to compare its efficacy with irinotecan. this study revealed that kaempferol could be safely used as a chemopreventive agent in colorectal cancer [2].

References

[1] martineti v, tognarini i, azzari c, carbonell sala s, clematis f, dolci m, lanzotti v, tonelli f, brandi ml, curir p. inhibition of in vitro growth and arrest in the g0/g1 phase of hct8 line human colon cancer cells by kaempferide triglycoside from dianthus caryophyllus. phytother res. 2010 sep;24(9):1302-8.
[2] nirmala p, ramanathan m. effect of kaempferol on lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal carcinoma in rats. eur j pharmacol. 2011 mar 1;654(1):75-9.

ARTEMISININ Preparation Products And Raw materials

Raw materials

Preparation Products

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ARTEMISININ Suppliers

Americas 1 China 189 Europe 1 France 1 Germany 2 India 4 Japan 2 United Kingdom 9 United States 21 USA 1 Global 231

Zhuo Ruining (Shanghai) Technology Co., Ltd

Tel: 18163338995
Email: 2605578685@qq.com
Country: China
ProdList: 495
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55013243 15324716602
Email: 2853979810@qq.com
Country: China
ProdList: 9562
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J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9552
Advantage: 66

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
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BEST-REAGENT

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Aktin Chemicals, Inc.

Tel: 86-28-85159085
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Shenzhen Sungening Bio-Tech Co., Ltd

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Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
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View Lastest Price from ARTEMISININ manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Kaempferide 491-54-3
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-12-27

Career Henan Chemical Co

Product: ARTEMISININ 491-54-3
Price: US $302.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000kg
Release date: 2018-07-27

491-54-3, ARTEMISININRelated Search:

KAEMPFEROL 3-A-L-ARABINOPYRANOSIDE KaeMpferol 3-sophoroside-7-rhaMnoside kaempferol 3-O-sophoroside Kaempferol 3-sophoroside-7-glucoside Kaempferol 3-(6-O-glucopyranosylglucoside) Kaempferol 3-neohesperidoside Kaempferol Ginkgo biloba extract FructussSophoraeExtract KAEMPFERITRIN KAEMPFEROL-3-O-RUTINOSIDE KAEMPFEROL-7-O-GLUCOSIDE 3,4'-DIMETHOXY-3',5,7-TRIHYDROXYFLAVONE CASTICIN Icariin TAMARIXETIN Arteannuin, Qinghaosu,Artemisine，Artemisinin，Arteannuin,ARTEANNUIN,(+)-Arteannuin,Arteannuin99% arteannuin B

4’-methylkaempferol

3,5,7-trihydroxy-2-(4-methoxyphenyl)-1-benzopyran-4-one

Kaempferide~3,5,7-Trihydroxy-4-methoxyflavone

3,5,7-trihydroxy-2-(4-methoxyphenyl)-4-benzopyrone

Kaemperide

3,5,7-Trihydroxy-2-(4-methoxy-phenyl)-chromen-4-

KAEMPFERIDE

ARTEMISIA ANNUA

ARTEMISIA P E

ARTEMISINE

ARTEMISININE

ARTEANUIN

ARTEANNUIN

KAEMPFERIDE hplc

4''-METHOXY-3,5,7-TRIHYDROXYFLAVONE 97%

KAEMPFERIDE WITH HPLC

3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one

3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one

Kempferide

[DISCONTINUED] Replaced by KIT-00010955-005

4’-o-methylkaempferol

kaempferid

SWEET WORMWOOD

QINGHAOSA

ALPHA BETA ARTEMISININ

4'-METHOXY-3,5,7-TRIHYDROXYFLAVONE

3,5,7-TRIHYDROXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE

KaeMpferol 4'-O-Methyl ether

KaeMpferide, froM KaeMpferia galanga

5,7-Dihydroxy-4'-Methoxyflavonol

CaMpheride

KaMpheride

3,5,7-trihydroxy-2-(4-methoxyphenyl)-4h-1-benzopyran-4-on

4’-methoxy-3,5,7-trihydroxy-flavanon

Kaempferide, 99%, from Kaempferia galanga

4'-MethoxykaeMpferol

Flavone,3,5,7-trihydroxy-4'-Methoxy-(7CI,8CI)

KaeMpferide(6CI)

KaeMpferol4

4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-methoxyphenyl)-

ARTEMISININ 491-54-3

Icaritin Impurity 1

491-54-3

Flavanols

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract