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ARTEMISININ

Product Name
ARTEMISININ
CAS No.
491-54-3
Chemical Name
ARTEMISININ
Synonyms
KAEMPFERIDE;ARTEANNUIN;ARTEMISIA ANNUA;kaempferid;ARTEANUIN;QINGHAOSA;Kaemperide;ARTEMISINE;Kempferide;CaMpheride
CBNumber
CB0387974
Molecular Formula
C16H12O6
Formula Weight
300.26
MOL File
491-54-3.mol
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ARTEMISININ Property

Melting point:
156-157 °C(lit.)
Boiling point:
543.8±50.0 °C(Predicted)
Density 
1.538
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly, Heated), DMSO (Slightly, Heated), Methanol (Slightly, Heat
pka
6.32±0.40(Predicted)
color 
Yellow
BRN 
305378
LogP
2.740 (est)
CAS DataBase Reference
491-54-3
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Safety

Safety Statements 
24/25
WGK Germany 
2
RTECS 
KD4170000
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
69545
Product name
Kaempferide
Purity
analytical standard
Packaging
10mg
Price
$548
Updated
2024/03/01
TCI Chemical
Product number
K0057
Product name
Kaempferide
Purity
>96.0%(GC)
Packaging
10mg
Price
$129
Updated
2024/03/01
TCI Chemical
Product number
K0057
Product name
Kaempferide
Purity
>96.0%(GC)
Packaging
50mg
Price
$385
Updated
2024/03/01
Cayman Chemical
Product number
29673
Product name
Kaempferide
Packaging
5mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
29673
Product name
Kaempferide
Packaging
10mg
Price
$121
Updated
2024/03/01
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ARTEMISININ Chemical Properties,Usage,Production

Chemical Properties

Yellow powder

Uses

Kaempferide is a flavonoid that maintains anti-radical and anti-oxidant capabilities, as well as anti-tumour possibilities. Impurity of Icaritin (I163700).

Definition

ChEBI: A monomethoxyflavone that is the 4'-O-methyl derivative of kaempferol.

Biological Activity

the effects of phytoestrogens have been studied in the hypothalamic-pituitary-gonadal axis and various non-gonadal targets. epidemiologic and experimental evidence indicates a protective effect of phytoestrogens also in colorectal cancer. the mechanism through which estrogenic molecules control colorectal cancer tumorigenesis could possibly involve estrogen receptor β, which is the predominantly expressed estrogen receptor subtype in colon mucosa.

in vitro

kaempferide triglycoside proved to inhibit the proliferation of native and estrogen receptor β overexpressing colon cancer cells via a mechanism not mediated by ligand binding dependent estrogen receptor activation. it affected hct8 cell cycle progression through increasing the g0/g1 cell fraction and in estrogen receptor β overexpressing cells increased two antioxidant enzymes [1].

in vivo

the aim of one previous study was to evaluate the effect of kaempferol on tissue lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal cancer in male wistar rats and to compare its efficacy with irinotecan. this study revealed that kaempferol could be safely used as a chemopreventive agent in colorectal cancer [2].

References

[1] martineti v, tognarini i, azzari c, carbonell sala s, clematis f, dolci m, lanzotti v, tonelli f, brandi ml, curir p. inhibition of in vitro growth and arrest in the g0/g1 phase of hct8 line human colon cancer cells by kaempferide triglycoside from dianthus caryophyllus. phytother res. 2010 sep;24(9):1302-8.
[2] nirmala p, ramanathan m. effect of kaempferol on lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal carcinoma in rats. eur j pharmacol. 2011 mar 1;654(1):75-9.

ARTEMISININ Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ARTEMISININ manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Kaempferide 491-54-3
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-12-27
Career Henan Chemical Co
Product
ARTEMISININ 491-54-3
Price
US $302.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2018-07-27

491-54-3, ARTEMISININRelated Search:

KAEMPFEROL 3-A-L-ARABINOPYRANOSIDE KaeMpferol 3-sophoroside-7-rhaMnoside kaempferol 3-O-sophoroside Kaempferol 3-sophoroside-7-glucoside Kaempferol 3-(6-O-glucopyranosylglucoside) Kaempferol 3-neohesperidoside Kaempferol Ginkgo biloba extract FructussSophoraeExtract KAEMPFERITRIN KAEMPFEROL-3-O-RUTINOSIDE KAEMPFEROL-7-O-GLUCOSIDE 3,4'-DIMETHOXY-3',5,7-TRIHYDROXYFLAVONE CASTICIN Icariin TAMARIXETIN Arteannuin, Qinghaosu,Artemisine，Artemisinin，Arteannuin,ARTEANNUIN,(+)-Arteannuin,Arteannuin99% arteannuin B

  • 4’-methylkaempferol
  • 3,5,7-trihydroxy-2-(4-methoxyphenyl)-1-benzopyran-4-one
  • Kaempferide~3,5,7-Trihydroxy-4-methoxyflavone
  • 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4-benzopyrone
  • Kaemperide
  • 3,5,7-Trihydroxy-2-(4-methoxy-phenyl)-chromen-4-
  • KAEMPFERIDE
  • ARTEMISIA ANNUA
  • ARTEMISIA P E
  • ARTEMISINE
  • ARTEMISININE
  • ARTEANUIN
  • ARTEANNUIN
  • KAEMPFERIDE hplc
  • 4''-METHOXY-3,5,7-TRIHYDROXYFLAVONE 97%
  • KAEMPFERIDE WITH HPLC
  • 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one
  • 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
  • Kempferide
  • [DISCONTINUED] Replaced by KIT-00010955-005
  • 4’-o-methylkaempferol
  • kaempferid
  • SWEET WORMWOOD
  • QINGHAOSA
  • ALPHA BETA ARTEMISININ
  • 4'-METHOXY-3,5,7-TRIHYDROXYFLAVONE
  • 3,5,7-TRIHYDROXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE
  • KaeMpferol 4'-O-Methyl ether
  • KaeMpferide, froM KaeMpferia galanga
  • 5,7-Dihydroxy-4'-Methoxyflavonol
  • CaMpheride
  • KaMpheride
  • 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4h-1-benzopyran-4-on
  • 4’-methoxy-3,5,7-trihydroxy-flavanon
  • Kaempferide, 99%, from Kaempferia galanga
  • 4'-MethoxykaeMpferol
  • Flavone,3,5,7-trihydroxy-4'-Methoxy-(7CI,8CI)
  • KaeMpferide(6CI)
  • KaeMpferol4
  • 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-methoxyphenyl)-
  • ARTEMISININ 491-54-3
  • Icaritin Impurity 1
  • 491-54-3
  • Flavanols
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract