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Icariin

Applications Description References
Product Name
Icariin
CAS No.
489-32-7
Chemical Name
Icariin
Synonyms
ICARIN;yyhxwz;ICARRIN;Icraiin;Icariil;Icariin;Icariln;ICARIINE;Iicariin;Ieariline
CBNumber
CB7345038
Molecular Formula
C33H40O15
Formula Weight
676.66
MOL File
489-32-7.mol
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Icariin Property

Melting point:
223-225 ºC
alpha 
D15 -87.09° (in pyridine)
Boiling point:
948.5±65.0 °C(Predicted)
Density 
1.55
RTECS 
DJ2980500
storage temp. 
room temp
solubility 
DMSO: soluble50mg/mL, clear, colorless to dark yellow
form 
Powder
pka
5.90±0.40(Predicted)
color 
light yellow to yellow
λmax
350nm(MeOH)(lit.)
Merck 
14,3617
InChIKey
TZJALUIVHRYQQB-XLRXWWTNSA-N
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
56601
Product name
Icariin
Purity
analytical standard
Packaging
25mg
Price
$283
Updated
2021/03/22
Sigma-Aldrich
Product number
I1286
Product name
Icariin
Purity
≥94% (HPLC)
Packaging
1g
Price
$741
Updated
2020/08/18
TCI Chemical
Product number
I0862
Product name
Icariin
Purity
>96.0%(HPLC)
Packaging
1g
Price
$343
Updated
2021/03/22
TCI Chemical
Product number
I0862
Product name
Icariin
Purity
>96.0%(HPLC)
Packaging
200mg
Price
$105
Updated
2021/03/22
Alfa Aesar
Product number
J66324
Product name
Icariin, 98%
Packaging
250mg
Price
$124
Updated
2021/03/22
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Icariin Chemical Properties,Usage,Production

Applications

Icariin inhibits the ROS-dependent JNK and p38 pathways.

Description

Icariin is one of the major flavonoids of the herb Epimedium, which has long been used in Tranditional Chinese Medicine to treat bone fracture and prevent osteoporosis. Research has shown that icariin should be an effective component for the bone-strengthening activity of the herb Epimedium, and one of the possible mechanisms for this activity is to stimulate the proliferation and enhance the osteogenic differentiation of marrow stromal cells. Icariin is reported to prevent and treat sexual dysfunction related diseases and improve the use of vasoconstriction. Icariin is used to prepare angiotensin converting enzyme inhibitor medicines, which can be used to treat hypertension-complicated coronary diseases.

References

[1] K. M. Chen, B. F. Ge, H. P. Ma, X. Y. Liu, M. H. Bai, Y, Wang (2005) Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells, 60, 939-942
[2] Patent CN 1199647C “Application of icariin in preparation of medicine for preventing and treating sexual dysfunction”
[3] Patent CN 104739851 A “New application of icariin, or icariin derivatives or icariin salt”

Chemical Properties

Light yellow to yellow solid

Uses

hepatoprotective

Icariin Preparation Products And Raw materials

Raw materials

Preparation Products

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Icariin Suppliers

Shaanxi Pioneer Biotech Co.,Ltd
Tel
29-84385017-8010
Email
sales@pioneerbiotech.com
Country
China
ProdList
279
Advantage
58
Shanghai Hewu Biotechnology Co., LTD
Tel
021-57886085
Email
shhebio@126.com
Country
CHINA
ProdList
7977
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3579
Advantage
66
Chembest Research Laboratories Limited
Tel
021-20908456-
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
5952
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057-
Fax
0757-86311057
Email
kennyrong@hwrkchemical.com
Country
China
ProdList
17296
Advantage
55
Nanjing Chemlin Chemical Co., Ltd
Tel
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19993
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202- ;021-54308259-
Fax
+86-21-64545202
Email
info@hanhonggroup.com;info@hanhonggroup.com
Country
China
ProdList
43255
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Email
sales@dongfan-chem.com
Country
China
ProdList
5702
Advantage
66
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View Lastest Price from Icariin manufacturers

NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
Icariin 489-32-7 489-32-7
Price
US $5.00/mg
Min. Order
20mg
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-07-16
NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
Icariin 489-32-7 489-32-7
Price
US $85.00/g
Min. Order
10mg
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-06-28
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Product
Icariin 489-32-7
Price
US $0.00/KG
Min. Order
100g
Purity
98%+
Supply Ability
100kg
Release date
2021-03-03

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