D-(-)-Salicin
Description- Product Name
- D-(-)-Salicin
- CAS No.
- 138-52-3
- Chemical Name
- D-(-)-Salicin
- Synonyms
- SALICIN;D-SALICIN;SALICOSIDE;WHITE WILLOW;Salicine;Salicylin;Salicin-RM;SALICIN(RG);SALICIN(SH);Salicin >
- CBNumber
- CB2349192
- Molecular Formula
- C13H18O7
- Formula Weight
- 286.28
- MOL File
- 138-52-3.mol
D-(-)-Salicin Property
- Melting point:
- 196-202 °C
- alpha
- -61.5 º (c=5, water)
- Boiling point:
- 388.65°C (rough estimate)
- Density
- 1.4340
- refractive index
- -62 ° (C=3, H2O)
- storage temp.
- 2-8°C
- solubility
- 36g/l
- form
- Fine Crystalline Powder
- pka
- 12.80±0.70(Predicted)
- color
- White
- Water Solubility
- 36 g/L (15 ºC), 250 g/L (60 ºC)
- Merck
- 14,8324
- BRN
- 89593
- Stability:
- Stable, but light sensitive. Incompatible with strong oxidizing agents.
- InChIKey
- NGFMICBWJRZIBI-MICYEWLZSA-N
- LogP
- -1.232 (est)
- CAS DataBase Reference
- 138-52-3(CAS DataBase Reference)
- NIST Chemistry Reference
- Salicin(138-52-3)
- EPA Substance Registry System
- .beta.-D-Glucopyranoside, 2-(hydroxymethyl)phenyl (138-52-3)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 43
- Safety Statements
- 36/37-37-24/25-36
- WGK Germany
- 3
- RTECS
- LZ5901700
- F
- 3-10
- TSCA
- Yes
- HS Code
- 29389090
N-Bromosuccinimide Price
- Product number
- S0625
- Product name
- D-(?)-Salicin
- Purity
- ≥99% (GC)
- Packaging
- 5g
- Price
- $57.1
- Updated
- 2024/03/01
- Product number
- 79588
- Product name
- D-(?)-Salicin
- Purity
- analytical standard
- Packaging
- 100mg
- Price
- $230
- Updated
- 2024/03/01
- Product number
- S0003
- Product name
- Salicin
- Purity
- >98.0%(HPLC)
- Packaging
- 5g
- Price
- $34
- Updated
- 2024/03/01
- Product number
- S0003
- Product name
- Salicin
- Purity
- >98.0%(HPLC)
- Packaging
- 25g
- Price
- $98
- Updated
- 2024/03/01
- Product number
- A16524
- Product name
- D-(-)-Salicin, 99%
- Packaging
- 5g
- Price
- $40.2
- Updated
- 2024/03/01
D-(-)-Salicin Chemical Properties,Usage,Production
Description
D(-)-Salicin is a traditional medicine which has been known to exhibit anti-inflammation and other therapeutic activities, it can inhibit the LPS-induced inflammation in RAW264.7 cells and mouse models.
Chemical Properties
white crystals or powder
Uses
analgesic, antipyretic
Uses
H1 antihistamine (nonsedating)
Uses
Standard substrate in evaluating enzyme Preparations contg b-glucosidase: Weidenhagen, Z. Ver. Zucker-Ind. 79, 591 (1929).
Uses
D-(-)-Salicin has been used:
- to study its in vitro anticoagulant and antiplatelet activities
- as a standard in high performance liquid chromatography method (HPLC) for quantitation of salicin from willow plant
- as a tastant in taste threshold assay
- as a constituent of nutrient agar-salicin medium for selective isolation of Lactobacillus paracasei
Definition
ChEBI: An aryl beta-D-glucoside that is the beta-D-glucoside of the phenolic hydroxy group of salicyl alcohol.
General Description
Salicin is a non-phenolic glucosidic compound extracted from meadowsweet (Filipendula ulmaria L). It is majorly used as a substitute for quinine. Salicin can be used as a therapeutic for patients suffering from rheumatic fever. Salicin acts a metabolic precursor for salicylic acid. It is a novel phytochemical that exhibits immunological cross functions in plants and humans. Salicin facilitates growth and reproduction in plants. In addition, It also protects plants against biotic and abiotic stress.
Biochem/physiol Actions
D-(?)-Salicin exerts anti-rheumatism and anti-inflammatory activities. It inhibits lipopolysaccharide (LPS) induced inflammation in in vitro and in vivo studies. It regulates different signaling pathways such as nuclear factor kappa B (NF-κB) and mitogen-activated protein kinase (MAPK). It also regulates cytokines concentration such as tumor necrosis factor-alpha(TNF-α), interleukin-1β, interleukin-6, and interleukin-10.
Purification Methods
Crystallise D(-)-salicin from EtOAc, EtOH or water and sublime it at 190-195o/12mm. [Armour et al. J Chem Soc 412 1961, IR: Pearl & Darling J Org Chem 24 731 1959, Beilstein 17 III/IV 2986, 17/7 V 113.]
D-(-)-Salicin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from D-(-)-Salicin manufacturers
- Product
- Salicin Powder 138-52-3
- Price
- US $150.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2024-11-18
- Product
- D-(-)-Salicin 138-52-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 10tons/month
- Release date
- 2024-07-09
- Product
- D-(-)-Salicin 138-52-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 15%-98% HPLC
- Supply Ability
- 1000KG
- Release date
- 2022-09-20