QUERCETINPENTAACETATE
- Product Name
- QUERCETINPENTAACETATE
- CAS No.
- 1064-06-8
- Chemical Name
- QUERCETINPENTAACETATE
- Synonyms
- Quercetin acetate;Pentaacetylquercetin;Quercetine pentaacetate;3,3',4',5,7-Pentaacetoxyflavone;3,3',4',5,7-Penta(acetyloxy)flavone;3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one;2-(3,4-diacetoxyphenyl)-4-oxo-4H-chromene-3,5,7-triyl triacetate;[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate;Quercetin pentaacetate,Respiratory syncytial virus,inhibit,Inhibitor,RSV;4H-1-Benzopyran-4-one, 3,5,7-tris(acetyloxy)-2-[3,4-bis(acetyloxy)phenyl]-
- CBNumber
- CB91405559
- Molecular Formula
- C25H20O12
- Formula Weight
- 512.42
- MOL File
- 1064-06-8.mol
QUERCETINPENTAACETATE Property
- Melting point:
- 193 °C
- Boiling point:
- 666.4±55.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Dichloromethane, Ethyl Acetate
- form
- Solid
- color
- Beige
N-Bromosuccinimide Price
- Product number
- 26694
- Product name
- Pentaacetylquercetin
- Packaging
- 10mg
- Price
- $48
- Updated
- 2024/03/01
- Product number
- 26694
- Product name
- Pentaacetylquercetin
- Packaging
- 500mg
- Price
- $1153
- Updated
- 2024/03/01
- Product number
- 26694
- Product name
- Pentaacetylquercetin
- Packaging
- 50mg
- Price
- $152
- Updated
- 2024/03/01
- Product number
- 26694
- Product name
- Pentaacetylquercetin
- Packaging
- 100mg
- Price
- $255
- Updated
- 2024/03/01
- Product number
- D454465
- Product name
- [5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl]Acetate
- Packaging
- 100mg
- Price
- $250
- Updated
- 2021/12/16
QUERCETINPENTAACETATE Chemical Properties,Usage,Production
Description
Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in vitro (IC50 = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC50 = 20.2 μg/ml). Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC50 = 8.7 μM) and PGE2 production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM. It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC50s = 38, 25, and 58 μM, respectively).
Uses
[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.