ChemicalBook > CAS DataBase List > 5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER

5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER

Product Name
5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER
CAS No.
860624-89-1
Chemical Name
5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER
Synonyms
Methyl 5-bromoindole-7-carboxylate;methyl 5-bromo-1H-indole-7-carboxylate;5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER;5-BroMo-1H-indol-7-carboxylic acid Methyl ester;5-Bromo-1H-indole-7-carboxylic acid methyl ester;1H-Indole-7-carboxylic acid, 5-bromo-, methyl ester;5-bromo-1H-Indole-7-carboxylic acid methyl ester (9CI ACI);1H-Indole-7-carboxylic acid, 5-bromo-, methyl ester (9CI, ACI)
CBNumber
CB1229352
Molecular Formula
C10H8BrNO2
Formula Weight
254.08
MOL File
860624-89-1.mol
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5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER Property

Boiling point:
382.6±22.0 °C(Predicted)
Density 
1.629±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
14.46±0.30(Predicted)
Appearance
Light yellow to brown Solid
CAS DataBase Reference
860624-89-1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Matrix Scientific
Product number
112522
Product name
Methyl 5-bromoindole-7-carboxylate
Packaging
1.00g
Price
$851
Updated
2026/05/18
Synthonix
Product number
M10611
Product name
Methyl 5-bromoindole-7-carboxylate
Purity
97.0%
Packaging
1g
Price
$60
Updated
2026/05/06
Synthonix
Product number
M10611
Product name
Methyl 5-bromoindole-7-carboxylate
Purity
97.0%
Packaging
5g
Price
$200
Updated
2026/05/06
Synthonix
Product number
M10611
Product name
Methyl 5-bromoindole-7-carboxylate
Purity
97.0%
Packaging
500mg
Price
$200
Updated
2026/05/06
Synthonix
Product number
M10611
Product name
Methyl 5-bromoindole-7-carboxylate
Purity
97.0%
Packaging
10g
Price
$400
Updated
2026/05/06
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5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

860624-90-4

74-88-4

860624-89-1

Iodomethane (7.81 mL, 125 mmol) was slowly added dropwise to a solution of N,N-dimethylformamide (50 mL) containing 5-bromo-1H-indole-7-carboxylic acid (10 g, 41.7 mmol) and sodium carbonate (17.66 g, 167 mmol). The reaction mixture was stirred continuously for 2 h at room temperature. Upon completion of the reaction, it was filtered through a silica gel pad (500 g) and eluted with ether (600 mL). The collected eluate was washed once with deionized water (100 mL) and subsequently concentrated under reduced pressure to afford methyl 5-bromoindole-7-carboxylate (9.65 g, 91% yield). The product was confirmed by LC/MS analysis: m/z 253.8 (M+), retention time 2.15 min.

References

[1] Patent: WO2008/118724, 2008, A1. Location in patent: Page/Page column 69-70
[2] ACS Medicinal Chemistry Letters, 2018,

5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER Suppliers

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View Lastest Price from 5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER manufacturers

Career Henan Chemical Co
Product
5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER 860624-89-1
Price
US $2.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
ask
Release date
2019-12-19

860624-89-1, 5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTERRelated Search:


  • 5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER
  • Methyl 5-bromoindole-7-carboxylate
  • methyl 5-bromo-1H-indole-7-carboxylate
  • 5-BroMo-1H-indol-7-carboxylic acid Methyl ester
  • 1H-Indole-7-carboxylic acid, 5-bromo-, methyl ester
  • 5-Bromo-1H-indole-7-carboxylic acid methyl ester
  • 1H-Indole-7-carboxylic acid, 5-bromo-, methyl ester (9CI, ACI)
  • 5-bromo-1H-Indole-7-carboxylic acid methyl ester (9CI ACI)
  • 860624-89-1