5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER
- Product Name
- 5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER
- CAS No.
- 860624-89-1
- Chemical Name
- 5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER
- Synonyms
- Methyl 5-bromoindole-7-carboxylate;methyl 5-bromo-1H-indole-7-carboxylate;5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER;5-BroMo-1H-indol-7-carboxylic acid Methyl ester;5-Bromo-1H-indole-7-carboxylic acid methyl ester;1H-Indole-7-carboxylic acid, 5-bromo-, methyl ester;5-bromo-1H-Indole-7-carboxylic acid methyl ester (9CI ACI);1H-Indole-7-carboxylic acid, 5-bromo-, methyl ester (9CI, ACI)
- CBNumber
- CB1229352
- Molecular Formula
- C10H8BrNO2
- Formula Weight
- 254.08
- MOL File
- 860624-89-1.mol
5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER Property
- Boiling point:
- 382.6±22.0 °C(Predicted)
- Density
- 1.629±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.46±0.30(Predicted)
- Appearance
- Light yellow to brown Solid
- CAS DataBase Reference
- 860624-89-1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 4H58-9-25
- Product name
- Methyl 5-bromoindole-7-carboxylate
- Packaging
- 250mg
- Price
- $225
- Updated
- 2021/12/16
- Product number
- 4H58-9-25
- Product name
- Methyl 5-bromoindole-7-carboxylate
- Packaging
- 1g
- Price
- $675
- Updated
- 2021/12/16
- Product number
- Z5207
- Product name
- Methyl5-bromoindole-7-carboxylate
- Packaging
- 250mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- HCH0105065
- Product name
- 5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1055.67
- Updated
- 2021/12/16
- Product number
- HCH0105065
- Product name
- 5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $2656.5
- Updated
- 2021/12/16
5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
860624-90-4
74-88-4
860624-89-1
Iodomethane (7.81 mL, 125 mmol) was slowly added dropwise to a solution of N,N-dimethylformamide (50 mL) containing 5-bromo-1H-indole-7-carboxylic acid (10 g, 41.7 mmol) and sodium carbonate (17.66 g, 167 mmol). The reaction mixture was stirred continuously for 2 h at room temperature. Upon completion of the reaction, it was filtered through a silica gel pad (500 g) and eluted with ether (600 mL). The collected eluate was washed once with deionized water (100 mL) and subsequently concentrated under reduced pressure to afford methyl 5-bromoindole-7-carboxylate (9.65 g, 91% yield). The product was confirmed by LC/MS analysis: m/z 253.8 (M+), retention time 2.15 min.
References
[1] Patent: WO2008/118724, 2008, A1. Location in patent: Page/Page column 69-70
[2] ACS Medicinal Chemistry Letters, 2018,
5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER manufacturers
- Product
- 5-BROMO INDOLE-7-CARBOXYLIC ACID METHYL ESTER 860624-89-1
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2019-12-19