9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2
- Product Name
- 9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2
- CAS No.
- 61263-35-2
- Chemical Name
- 9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2
- Synonyms
- U 46785;METENPROST;meteneprost;meteneprostum;9-Deoxy-16,16-diMethyl-9-Methylene-PGF2;9-Deoxo-9-Methylene-16,16-diMethyl-PGE2;9-deoxo-16,16-dimethyl-9-methylene-pge2;9-deoxo-16,16-dimethyl-9-methyleneprostaglandine2;9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2;9-Deoxo-16,16-dimethyl-9-methyleneprostaglandine E2
- CBNumber
- CB1229488
- Molecular Formula
- C23H38O4
- Formula Weight
- 378.55
- MOL File
- 61263-35-2.mol
9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2 Property
- Boiling point:
- 426.61°C (rough estimate)
- Density
- 1.0037 (rough estimate)
- refractive index
- 1.4433 (estimate)
- storage temp.
- Store at -20°C
- solubility
- DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2)
- pka
- 4.76±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
H336May cause drowsiness or dizziness
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 14420
- Product name
- 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $51
- Updated
- 2024/03/01
- Product number
- 14420
- Product name
- 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $97
- Updated
- 2024/03/01
- Product number
- 14420
- Product name
- 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $380
- Updated
- 2024/03/01
- Product number
- 14420
- Product name
- 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $657
- Updated
- 2024/03/01
- Product number
- M225570
- Product name
- Meteneprost
- Packaging
- 10mg
- Price
- $20350
- Updated
- 2021/12/16
9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2 Chemical Properties,Usage,Production
Uses
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 (PGE2; ) with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimester of pregnancy. Meteneprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.
Uses
Meteneprost is a potent analog of Prostaglandin E2 (PGE2) (P838610). Meteneprost in combination with various other prostaglandin derivatives is used for medical termination of early pregnancy.
Definition
ChEBI: 9-Deoxy-9-methylene-16,16-dimethyl -PGE2 is a long-chain fatty acid.
9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2 Preparation Products And Raw materials
Raw materials
Preparation Products
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