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ETPI HCL

Product Name
ETPI HCL
CAS No.
163490-78-6
Chemical Name
ETPI HCL
Synonyms
ETPI HCL;TFPI HCL;EPIT HCL;SEPIT HCL;hnNOS-IN-3;ETPI, HYDROCHLORIDE;TFPI hydrochloride;S-ETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]-ISOTHIOUREA, HCL;S-EthylN-[4-Triflurormethyl)phenyl]isothiourea,hydrochloride;S-ETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]ISOTHIOUREA HYDROCHLORIDE
CBNumber
CB1235605
Molecular Formula
C10H12ClF3N2S
Formula Weight
284.73
MOL File
163490-78-6.mol
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ETPI HCL Property

Melting point:
143-147 °C
storage temp. 
0-6°C
solubility 
DMF: >54 mg/ml; DMSO: >33.6 mg/ml; Ethanol: >55 mg/ml; Ethanol:PBS (pH 7.2) 1:3: 1 mg/ml; PBS pH 7.2: <50 μg/ml; Water: 50 mg/ml
form 
White to off-white solid.
CAS DataBase Reference
163490-78-6
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Safety

Safety Statements 
24/25
HS Code 
29309099
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
81280
Product name
S-ethyl N-[4-(trifluoromethyl)phenyl] Isothiourea (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
81280
Product name
S-ethyl N-[4-(trifluoromethyl)phenyl] Isothiourea (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
81280
Product name
S-ethyl N-[4-(trifluoromethyl)phenyl] Isothiourea (hydrochloride)
Purity
≥98%
Packaging
25mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
81280
Product name
S-ethyl N-[4-(trifluoromethyl)phenyl] Isothiourea (hydrochloride)
Purity
≥98%
Packaging
100mg
Price
$426
Updated
2024/03/01
TRC
Product number
E930500
Product name
S-EthylN-[4-Triflurormethyl)phenyl]isothioUrea,Hydrochloride
Packaging
100mg
Price
$330
Updated
2021/12/16
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ETPI HCL Chemical Properties,Usage,Production

Chemical Properties

white to off-white solid

Uses

EPIT is a selective, competitive inhibitor of nNOS having a Ki of 0.32 μM for the purified human enzyme. EPIT exhibits 115-fold and 29-fold selectivity for nNOS compared to iNOS and eNOS, respectively. It exhibits reduced inhibitory potency in whole-cell assays, possibly due to reduced intracellular uptake.

Uses

A selective inhibitor of nNOS (NOS I) relative to iNOS (NOS II) (115-fold) and eNOS (NOS III) (29-fold). It also binds competitively with L-Arginine.

ETPI HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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ETPI HCL Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

163490-78-6, ETPI HCLRelated Search:


  • EPIT HCL
  • ETHYL[4-(TRIFLUOROMETHYL)PHENYL] CARBAMIMIDOTHIOATE, HYDROCHLORIDE
  • ETPI HCL
  • ETPI, HYDROCHLORIDE
  • TFPI HCL
  • S-ETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]-ISOTHIOUREA, HCL
  • S-ETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]ISOTHIOUREA HYDROCHLORIDE
  • S-ETHYL N-[4-(TRIFLUORORMETHYL)PHENYL]ISOTHIOUREA, HYDROCHLORIDE
  • SEPIT HCL
  • S-EthylN-[4-Triflurormethyl)phenyl]isothiourea,hydrochloride
  • S-Ethyl-N-[4-(trifluoromethyl)phenyl]-isothiourea hydrochloride,98%
  • TFPI hydrochloride
  • Ethyl N'-(4-(trifluoromethyl)phenyl)carbamimidothioate hydrochloride
  • Carbamimidothioic acid, N-[4-(trifluoromethyl)phenyl]-, ethyl ester, hydrochloride (1:1)
  • hnNOS-IN-3
  • 163490-78-6
  • C10H12ClF3N2S
  • C10H11N2SF3HCl
  • C10H11F3N2SHCl
  • Nitric Oxide Reagents