ETPI HCL

Product Name: ETPI HCL
CAS No.: 163490-78-6
Chemical Name: ETPI HCL
Synonyms: ETPI HCL;TFPI HCL;EPIT HCL;SEPIT HCL;hnNOS-IN-3;ETPI, HYDROCHLORIDE;TFPI hydrochloride;S-ETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]-ISOTHIOUREA, HCL;S-EthylN-[4-Triflurormethyl)phenyl]isothiourea,hydrochloride;S-ETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]ISOTHIOUREA HYDROCHLORIDE
CBNumber: CB1235605
Molecular Formula: C10H12ClF3N2S
Formula Weight: 284.73
MOL File: 163490-78-6.mol

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ETPI HCL Property

Melting point:: 143-147 °C
storage temp.: 0-6°C
solubility: DMF: >54 mg/ml; DMSO: >33.6 mg/ml; Ethanol: >55 mg/ml; Ethanol:PBS (pH 7.2) 1:3: 1 mg/ml; PBS pH 7.2: <50 μg/ml; Water: 50 mg/ml
form: White to off-white solid.
CAS DataBase Reference: 163490-78-6

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Safety

Safety Statements: 24/25
HS Code: 29309099

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 81280
Product name: S-ethyl N-[4-(trifluoromethyl)phenyl] Isothiourea (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 81280
Product name: S-ethyl N-[4-(trifluoromethyl)phenyl] Isothiourea (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 81280
Product name: S-ethyl N-[4-(trifluoromethyl)phenyl] Isothiourea (hydrochloride)
Purity: ≥98%
Packaging: 25mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 81280
Product name: S-ethyl N-[4-(trifluoromethyl)phenyl] Isothiourea (hydrochloride)
Purity: ≥98%
Packaging: 100mg
Price: $426
Updated: 2024/03/01

TRC

Product number: E930500
Product name: S-EthylN-[4-Triflurormethyl)phenyl]isothioUrea,Hydrochloride
Packaging: 100mg
Price: $330
Updated: 2021/12/16

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ETPI HCL Chemical Properties,Usage,Production

Chemical Properties

white to off-white solid

Uses

EPIT is a selective, competitive inhibitor of nNOS having a Ki of 0.32 μM for the purified human enzyme. EPIT exhibits 115-fold and 29-fold selectivity for nNOS compared to iNOS and eNOS, respectively. It exhibits reduced inhibitory potency in whole-cell assays, possibly due to reduced intracellular uptake.

Uses

A selective inhibitor of nNOS (NOS I) relative to iNOS (NOS II) (115-fold) and eNOS (NOS III) (29-fold). It also binds competitively with L-Arginine.

IC 50

nNOS: 0.32 μM (Ki); eNOS: 9.4 μM (Ki); iNOS: 37 μM (Ki)

ETPI HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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ETPI HCL Suppliers

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163490-78-6, ETPI HCLRelated Search:

ETPI HCL S-ethyl N-(4-(trifluoromethyl)phenyl)isothiourea

EPIT HCL

ETHYL[4-(TRIFLUOROMETHYL)PHENYL] CARBAMIMIDOTHIOATE, HYDROCHLORIDE

ETPI HCL

ETPI, HYDROCHLORIDE

TFPI HCL

S-ETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]-ISOTHIOUREA, HCL

S-ETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]ISOTHIOUREA HYDROCHLORIDE

S-ETHYL N-[4-(TRIFLUORORMETHYL)PHENYL]ISOTHIOUREA, HYDROCHLORIDE

SEPIT HCL

S-EthylN-[4-Triflurormethyl)phenyl]isothiourea,hydrochloride

S-Ethyl-N-[4-(trifluoromethyl)phenyl]-isothiourea hydrochloride,98%

TFPI hydrochloride

Ethyl N'-(4-(trifluoromethyl)phenyl)carbamimidothioate hydrochloride

Carbamimidothioic acid, N-[4-(trifluoromethyl)phenyl]-, ethyl ester, hydrochloride (1:1)

hnNOS-IN-3

163490-78-6

C10H12ClF3N2S

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C10H11F3N2SHCl

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