5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE
- Product Name
- 5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE
- CAS No.
- 298181-83-6
- Chemical Name
- 5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE
- Synonyms
- 8-Amino-5;AKOS BB-8710;5,6,7,8-Tetrahydro-8-quinolinamine;5,6,7,8-tetrahydroquinolin-2-amine;8-quinolinamine,5,6,7,8-tetrahydro;5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE;8-AMino-5,6,7,8-tetrahydroquinoline;5,6,7,8-Tetrahydro-8-aminoquinoline;5,6,7,8-TETRAHYDRO-QUINOLIN-8-YLAMINE;8-Quinolinamine,5,6,7,8-tetrahydro-(9CI)
- CBNumber
- CB1240562
- Molecular Formula
- C9H12N2
- Formula Weight
- 148.21
- MOL File
- 298181-83-6.mol
5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE Property
- Boiling point:
- 277.3±28.0 °C(Predicted)
- Density
- 1.081±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 8.93±0.20(Predicted)
- Appearance
- Light brown to brown Liquid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T304080
- Product name
- 5,6,7,8-tetrahydroquinolin-8-amine
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- OR930035
- Product name
- 5,6,7,8-Tetrahydroquinolin-8-amine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 119687
- Product name
- 5,6,7,8-Tetrahydroquinolin-8-amine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $202
- Updated
- 2021/12/16
- Product number
- 3H30-1-PP
- Product name
- 5,6,7,8-Tetrahydroquinolin-8-amine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $288
- Updated
- 2021/12/16
- Product number
- 119687
- Product name
- 5,6,7,8-Tetrahydroquinolin-8-amine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $504
- Updated
- 2021/12/16
5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE Chemical Properties,Usage,Production
Synthesis Reference(s)
Synthetic Communications, 33, p. 3497, 2003 DOI: 10.1081/SCC-120024729
Synthesis
58509-59-4
298181-83-6
General procedure for the synthesis of 5,6,7,8-tetrahydro-8-aminoquinolines from 6,7-dihydroquinolin-8(5H)-one oxime: 6,7-dihydro-8(5H)-quinolinone oxime (0.50 g, 3.1 mmol) was dissolved in 35 mL of methanol and 50 mg 10% Pd/C catalyst was added. The catalytic hydrogenation reaction was carried out at 50 psi hydrogen pressure. After 18 hours of reaction, the hydrogen in the reaction system was replaced with nitrogen and the reaction mixture was filtered through a diatomaceous earth pad to remove the catalyst. The filtrate was concentrated to dryness under reduced pressure to give 0.42 g (92% yield) of 5,6,7,8-tetrahydro-8-aminoquinoline as a purple oil.1H NMR (CDCl3) δ: 8.39 (d, 1H), 7.36 (d, 1H), 7.04 (m, 1H), 4.00 (t, 1H), 2.88-2.67 (m, 2H), 2.18 (m, 1H), 2.03-1.62 (m, 5H).
References
[1] Patent: WO2006/20415, 2006, A1. Location in patent: Page/Page column 112
[2] Synthetic Communications, 2003, vol. 33, # 20, p. 3497 - 3502
[3] Organic Process Research and Development, 2008, vol. 12, # 5, p. 823 - 830
[4] Chemical Communications, 2016, vol. 52, # 38, p. 6423 - 6426
5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE Suppliers
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- 021-64968085,64968086-5815,5812; 13472757003
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- +86 21 64968087
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- China
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- sales@witofly.com
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- +86-28-85122536 85324413
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- 031185291771 13832391721
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- 0311-67305698
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- 400-164-7117 13681763483
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- +86-21-61629029
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- China
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- 15121041756
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- China
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- 021-61478794
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- 021-61478794
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- China
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- 13391076197
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- China
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View Lastest Price from 5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE manufacturers
- Product
- 5,6,7,8-TETRAHYDROQUINOLIN-8-AMINE 298181-83-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,100kg
- Release date
- 2019-07-04