ChemicalBook > CAS DataBase List > 5,6,7,8-Tetrahydroquinolin-8-ol

5,6,7,8-Tetrahydroquinolin-8-ol

Product Name
5,6,7,8-Tetrahydroquinolin-8-ol
CAS No.
14631-46-0
Chemical Name
5,6,7,8-Tetrahydroquinolin-8-ol
Synonyms
in-8-oL;Tetrahydro-quinolin-8-ol;5,6,7,8-tetrahydro-8-Quinolinol;8-quinolinol,5,6,7,8-tetrahydro-;5,6,7,8-TETRAHYDRO-QUINOLIN-8-OL;5,6,7,8-Tetrahydroquinoline-8-ol;5,6,7,8-Tetrahydroquinolin-8-ol ISO 9001:2015 REACH
CBNumber
CB7313095
Molecular Formula
C9H11NO
Formula Weight
149.19
MOL File
14631-46-0.mol
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5,6,7,8-Tetrahydroquinolin-8-ol Property

Melting point:
64-65 °C
Boiling point:
88-96 °C(Press: 2 Torr)
Density 
1.179±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
solid
pka
13.44±0.20(Predicted)
Appearance
Off-white to yellow Solid
InChI
1S/C9H11NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h2,4,6,8,11H,1,3,5H2
InChIKey
YCQHYOBSOVFBEB-UHFFFAOYSA-N
SMILES
OC1CCCc2cccnc12
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN2811
WGK Germany 
WGK 3
HazardClass 
6.1
HS Code 
2933499090
Storage Class
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications
Acute Tox. 3 Oral
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS003538
Product name
5,6,7,8-tetrahydro-quinolin-8-ol
Purity
AldrichCPR
Packaging
250MG
Price
$70.4
Updated
2026/04/30
AstaTech
Product number
66602
Product name
5,6,7,8-TETRAHYDRO-QUINOLIN-8-OL
Purity
97%
Packaging
5G
Price
$45
Updated
2026/04/30
AstaTech
Product number
66602
Product name
5,6,7,8-TETRAHYDRO-QUINOLIN-8-OL
Purity
97%
Packaging
25G
Price
$217
Updated
2026/04/30
AstaTech
Product number
66602
Product name
5,6,7,8-TETRAHYDRO-QUINOLIN-8-OL
Purity
97%
Packaging
4*25G
Price
$587
Updated
2026/04/30
Apolloscientific
Product number
OR300368
Product name
5,6,7,8-Tetrahydroquinolin-8-ol
Purity
≥95%
Packaging
1g
Price
$21
Updated
2026/06/04
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5,6,7,8-Tetrahydroquinolin-8-ol Chemical Properties,Usage,Production

Chemical Properties

off-white crytalline

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 15, p. 249, 1978 DOI: 10.1002/jhet.5570150213

Synthesis

130861-73-3

14631-46-0

General procedure for the synthesis of 5,6,7,8-tetrahydro-8-hydroxyquinolines from 2-chloro-5,6,7,8-tetrahydroquinolin-8-ol: a generalized method was employed using PdCl2 (dppf), PdCl2 (tbpf), or (A.caPhos) PdCl2 as catalyst. First, the halogenated heterocyclic compound (0.66 mmol) was dissolved in anhydrous THF (13.2 mL) and degassed by drumming argon for a few minutes. Subsequently, PdCl2 (dppf) (27.0 mg, 0.033 mmol, 5.0 mol%), TMEDA (0.130 g, 1.12 mmol, 1.7 equiv) and NaBH4 (42.4 mg, 1.12 mmol, 1.7 equiv) were added sequentially. The reaction mixture was stirred under argon protection at room temperature for an appropriate time, after which it was post-treated as described above.

References

[1] Tetrahedron Letters, 2010, vol. 51, # 12, p. 1562 - 1565
[2] Journal of Molecular Catalysis A: Chemical, 2014, vol. 393, p. 191 - 209

5,6,7,8-Tetrahydroquinolin-8-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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5,6,7,8-Tetrahydroquinolin-8-ol Suppliers

J & K SCIENTIFIC LTD.
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View Lastest Price from 5,6,7,8-Tetrahydroquinolin-8-ol manufacturers

Career Henan Chemical Co
Product
5,6,7,8-Tetrahydroquinolin-8-ol 14631-46-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-09