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Tetrahydrothiophene

Product Name
Tetrahydrothiophene
CAS No.
110-01-0
Chemical Name
Tetrahydrothiophene
Synonyms
THT;Tetrahydrothiophen;Thiophene, tetrahydro-;THIOLANE;THIOPHANE;TETRAMETHYLENE SULFIDE;TETRAHYDROTHIOPHEN 99%(GC);Thilane;Thiofan;THIOLAN
CBNumber
CB9402977
Molecular Formula
C4H8S
Formula Weight
88.17
MOL File
110-01-0.mol
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Tetrahydrothiophene Property

Melting point:
-96 °C (lit.)
Boiling point:
119 °C (lit.)
Density 
1 g/mL at 25 °C (lit.)
vapor pressure 
18 mm Hg ( 25 °C)
refractive index 
n20/D 1.504(lit.)
Flash point:
55 °F
storage temp. 
Store below +30°C.
solubility 
immiscible
form 
liquid
Specific Gravity
1.002 (20/4℃)
color 
Colorless to Almost colorless
Odor
Smells of rotting eggs
PH
7 (H2O, 20℃)
explosive limit
1.1-12.1%(V)
Odor Threshold
0.00062ppm
Odor Type
sulfurous
Water Solubility 
immiscible
Merck 
14,9218
BRN 
102392
Dielectric constant
8.6099999999999994
Stability:
Highly flammable. Vapour-air mixtures explosive in some proportions; note low flash point and fairly wide explosion limit range. Heavier than air, so potentially explosive mixtures may travel considerable distances to source of ignition.
LogP
1.8 at 20℃
CAS DataBase Reference
110-01-0(CAS DataBase Reference)
NIST Chemistry Reference
Thiophene, tetrahydro-(110-01-0)
EPA Substance Registry System
Tetrahydrothiophene (110-01-0)
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Safety

Hazard Codes 
F,Xn
Risk Statements 
11-20/21/22-36/38-52/53
Safety Statements 
16-23-36/37-61
RIDADR 
UN 2412 3/PG 2
WGK Germany 
2
RTECS 
XN0370000
Autoignition Temperature
202 °C
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29349990
Hazardous Substances Data
110-01-0(Hazardous Substances Data)
Toxicity
LD50 by inhalation in mice: 26.7 mg/l (Carlucci)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T15601
Product name
Tetrahydrothiophene
Purity
99%
Packaging
5g
Price
$36.4
Updated
2024/03/01
Sigma-Aldrich
Product number
T15601
Product name
Tetrahydrothiophene
Purity
99%
Packaging
100g
Price
$67
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21095
Product name
Tetrahydrothiophene
Purity
for synthesis
Packaging
5ml
Price
$22.3
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21095
Product name
Tetrahydrothiophene
Purity
for synthesis
Packaging
250ML
Price
$55.8
Updated
2024/03/01
TCI Chemical
Product number
T0114
Product name
Tetrahydrothiophene
Purity
>99.0%(GC)
Packaging
25mL
Price
$16
Updated
2024/03/01
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Tetrahydrothiophene Chemical Properties,Usage,Production

Chemical Properties

Tetrahydrothiophene is cyclic thioalkane, namely, saturated analog of thiophene. It is a colorless transparent volatile liquid, insoluble in water, miscible in ethanol, ether, benzene, acetone. It has a strong unpleasant odor, is stable and not easily emitted, and can be smelled in the air at 0.01PPm. It is not corrosive to gas equipment, transportation pipeline gaskets and other materials, and does not produce habitual blunting of the human sense of smell, so it is used as an odorant in LPG and natural gas, outlawing the original use of ethyl mercaptan and other odor-assigning agents.

Uses

Tetrahydrothiophene is a solvent and a fuel gas odorant used in fire safety stench warning systems in underground mines. Tetrahydrothiophene was also used as an organocatalyst for the reaction between enynediones and benzoic acid to afford highly substituted furfuryl alcohol benzoates.

Uses

Tetrahydrothiophene is used as pharmaceutical and agrochemical intermediates.

Preparation

Tetrahydrothiophene is prepared by the reaction of hydrogen sulfide and furan in the vapor phase at 400°C. This vapor-phase reaction is catalyzed by alumina(Al2O3) and other heterogenous acid catalysts.

Definition

ChEBI: Tetrahydrothiophene is a saturated organic heteromonocyclic parent and a member of tetrahydrothiophenes.

General Description

A water-white liquid. About the same density as water and insoluble in water. Flash point near 20°F. Vapors heavier than air. Used as a solvent and to make other chemicals.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Organosulfides, such as Tetrahydrothiophene, are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Slow addition of hydrogen peroxide to the thiophene resulted in explosions on three occasions, Chem. Eng. News, 1974, 52(39), 3.

Health Hazard

May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Mildly toxic by inhalation. Flammable liquid. Potentially explosive reaction with hydrogen peroxide. When heated to decomposition it emits toxic fumes of SOx.

Purification Methods

The crude material is purified by crystallisation of the mercuric chloride complex to a constant melting point. It is then regenerated, washed, dried, and fractionally distilled. [Whitehead et al. J Am Chem Soc 73 3632 1951.] It has been dried over Na2SO4 and distilled in a vacuum [Roberts & Friend J Am Chem Soc 108 7204 1986]. [Beilstein 17 I 5, 17 II 15, 17 III/IV 34, 17/1 V 36.]

Tetrahydrothiophene Preparation Products And Raw materials

Raw materials

Preparation Products

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Tetrahydrothiophene Suppliers

Shandong Xuchen Chemical Technology Co. Ltd
Tel
0533-13853380-763 13853380763
Email
3523649491@qq.com
Country
China
ProdList
390
Advantage
58
SHANDONGQIANGSENHUAGONG
Tel
0533-18369966222-222 18369966222
Email
3034942636@qq.com
Country
China
ProdList
922
Advantage
58
Shandong Jinhe Chemical Co., Ltd
Tel
18369966633
Email
81505319@qq.com
Country
China
ProdList
194
Advantage
58
ZI BO YUJIN TRADING CO.,LTD
Tel
18805331268
Email
691775164@qq.com
Country
China
ProdList
508
Advantage
58
Shandong Hima Supply chain Management Co., LTD
Tel
13011607593
Email
904987017@qq.com
Country
China
ProdList
402
Advantage
58
Jinan Hongtai Weiye Trading Co., Ltd
Tel
15954911888
Email
2660943764@qq.com
Country
China
ProdList
30
Advantage
58
Shandong Johnson Chemical Co., LTD
Tel
0533-1516922-6111 15169226111
Email
676807278@qq.com
Country
China
ProdList
748
Advantage
58
ZIBO LISHUO CHEMICAL
Tel
13853320569
Email
z1184400177@163.com
Country
China
ProdList
833
Advantage
58
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
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View Lastest Price from Tetrahydrothiophene manufacturers

Hebei Jingbo New Material Technology Co., Ltd
Product
Tetrahydrothiophene 110-01-0
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
200000
Release date
2023-11-29
Hebei Yanxi Chemical Co., Ltd.
Product
Tetrahydrothiophene 110-01-0
Price
US $25.00-10.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-11-21
Hebei Chuanghai Biotechnology Co,.LTD
Product
Tetrahydrothiophene 110-01-0
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-23

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