ChemicalBook > CAS DataBase List > D-BIOTIN P-NITROPHENYL ESTER

D-BIOTIN P-NITROPHENYL ESTER

Product Name
D-BIOTIN P-NITROPHENYL ESTER
CAS No.
33755-53-2
Chemical Name
D-BIOTIN P-NITROPHENYL ESTER
Synonyms
BNP;PBNP;BIOTIN-ONP;(+)-Biotin-ONP;Biotin-ONp Novabiochem;BIOTIN P-NITROPHENYL ESTER;Biotin π-nitrophenyl ester;4-NITROPHENYL (+)-BIOTINATE;D-BIOTIN P-NITROPHENYL ESTER;biotinyl-4-nitrophenyl ester
CBNumber
CB1101472
Molecular Formula
C16H19N3O5S
Formula Weight
365.4
MOL File
33755-53-2.mol
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D-BIOTIN P-NITROPHENYL ESTER Property

Melting point:
163-165 °C(lit.)
Boiling point:
642.9±50.0 °C(Predicted)
Density 
1.326±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
methanol: soluble25mg/mL, clear, colorless to greenish-yellow
pka
13.89±0.40(Predicted)
form 
Solid
color 
White to Off-White
optical activity
[α]25/D +51°, c = 2 in DMF: AcOH (99:1)
BRN 
5795805
InChIKey
YUDNXDTXQPYKCA-OWYJLGKBSA-N
CAS DataBase Reference
33755-53-2
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
10-21
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H290May be corrosive to metals

Precautionary statements

P234Keep only in original container.

P390Absorb spillage to prevent material damage.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
WH0004879M1
Product name
Monoclonal Anti-NPPB antibody produced in mouse
Purity
clone 2D11, purified immunoglobulin, buffered aqueous solution
Packaging
100μG
Price
$524
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB5300236
Product name
Monoclonal Anti-NPPB antibody produced in mouse
Purity
clone 3A6F7C7, ascites fluid
Packaging
100μL
Price
$524
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB5300235
Product name
Monoclonal Anti-NPPB antibody produced in mouse
Purity
clone 9H6B4, ascites fluid
Packaging
100μL
Price
$524
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB5300234
Product name
Monoclonal Anti-NPPB antibody produced in mouse
Purity
clone 8D5B4C11, ascites fluid
Packaging
100μL
Price
$524
Updated
2024/03/01
Sigma-Aldrich
Product number
RAB0386
Product name
Brain Natriuretic Peptide EIA Kit
Purity
for serum, plasma, culture supernatant and cell lysates
Packaging
1KIT
Price
$523
Updated
2024/03/01
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D-BIOTIN P-NITROPHENYL ESTER Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

(+)-Biotin 4-nitrophenyl ester may be used in the preparation of biotin tagged ARC (adenosine-oligoarginine conjugate) derivative during cellular protein uptake studies. It may also be used to prepare biotinylated quinazoline derivatives, which shows inhibitory activities against VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinase. (+)-Biotin 4-nitrophenyl ester undergoes hydrolysis in the presence of Na[17O]H to form [17O2]biotin, which can be used in solid-state 17O NMR spectroscopic experiments to analyze large protein-ligand complexes.

Uses

For research use only. Not for use in diagnostic procedures.
Brain natriuretic peptide EIA Kit has been used to measure brain natriuretic peptide (BNP) secreted in human neonatal ventricular cardiomyocyte culture.

General Description

The BNP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting BNP peptide based on the principle of Competitive Enzyme Immunoassay.

Biochem/physiol Actions

Brain natriuretic peptide (BNP) expressed in mammalian brain and atrial natriuretic peptide (ANP) facilitates various physiological functions including regulation of blood pressure and cardiac remodeling. BNP acts as a potential biomarker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular (LV) dysfunction. Elevated expression of BNP is observed in acute myocardial infarction (AMI) patients. BNP is also implicated in several biological functions such as diuresis, natriureis, hypotensive action and inhibition of aldosterone secretion.

Purification Methods

The ester has been recrystallised by dissolving 2g in 95% EtOH (30mL), heated to dissolve, then cooled in an ice-water bath. The crystals are collected, washed with ice-cold 95% EtOH (5mL) and dried over P2O5. The RF on silica plates (CHCl3/MeOH 19:1) is 0.19 [Bodanszky & Fagan J Am Chem Soc 99 235 1977].

D-BIOTIN P-NITROPHENYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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D-BIOTIN P-NITROPHENYL ESTER Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Hangzhou Yuhao Chemical Technology Co., Ltd
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0571-82693216
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+86-571-82880190
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Hangzhou Sage Chemical Co., Ltd.
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+86057186818502 13588463833
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View Lastest Price from D-BIOTIN P-NITROPHENYL ESTER manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
D-BIOTIN P-NITROPHENYL ESTER 33755-53-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-15
Zhuozhou Wenxi import and Export Co., Ltd
Product
BNP 33755-53-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
BNP 33755-53-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

33755-53-2, D-BIOTIN P-NITROPHENYL ESTERRelated Search:


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