ChemicalBook > CAS DataBase List > D-BIOTIN P-NITROPHENYL ESTER

D-BIOTIN P-NITROPHENYL ESTER

Description Source Background

Product Name: D-BIOTIN P-NITROPHENYL ESTER
CAS No.: 33755-53-2
Chemical Name: D-BIOTIN P-NITROPHENYL ESTER
Synonyms: BNP;PBNP;BIOTIN-ONP;(+)-Biotin-ONP;Biotin-ONp Novabiochem;BIOTIN P-NITROPHENYL ESTER;Biotin π-nitrophenyl ester;4-NITROPHENYL (+)-BIOTINATE;biotinyl-4-nitrophenyl ester;D-BIOTIN P-NITROPHENYL ESTER
CBNumber: CB1101472
Molecular Formula: C16H19N3O5S
Formula Weight: 365.4
MOL File: 33755-53-2.mol

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D-BIOTIN P-NITROPHENYL ESTER Property

Melting point:: 163-165 °C(lit.)
Boiling point:: 642.9±50.0 °C(Predicted)
Density: 1.326±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: methanol: soluble25mg/mL, clear, colorless to greenish-yellow
pka: 13.89±0.40(Predicted)
form: Solid
color: White to Off-White
biological source: mouse
optical activity: [α]25/D +51°, c = 2 in DMF: AcOH (99:1)
BRN: 5795805
InChIKey: YUDNXDTXQPYKCA-OWYJLGKBSA-N
CAS DataBase Reference: 33755-53-2

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10-21
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H290May be corrosive to metals

Precautionary statements

P234Keep only in original container.

P390Absorb spillage to prevent material damage.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: WH0004879M1
Product name: Monoclonal Anti-NPPB antibody produced in mouse
Purity: clone 2D11, purified immunoglobulin, buffered aqueous solution
Packaging: 100μG
Price: $541
Updated: 2025/07/31

Sigma-Aldrich

Product number: SAB5300236
Product name: Monoclonal Anti-NPPB antibody produced in mouse
Purity: clone 3A6F7C7, ascites fluid
Packaging: 100μL
Price: $406
Updated: 2025/07/31

Sigma-Aldrich

Product number: SAB5300235
Product name: Monoclonal Anti-NPPB antibody produced in mouse
Purity: clone 9H6B4, ascites fluid
Packaging: 100μL
Price: $541
Updated: 2025/07/31

Sigma-Aldrich

Product number: SAB5300234
Product name: Monoclonal Anti-NPPB antibody produced in mouse
Purity: clone 8D5B4C11, ascites fluid
Packaging: 100μL
Price: $541
Updated: 2025/07/31

Sigma-Aldrich

Product number: RAB0386
Product name: Brain Natriuretic Peptide EIA Kit
Purity: for serum, plasma, culture supernatant and cell lysates
Packaging: 1KIT
Price: $540
Updated: 2025/07/31

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D-BIOTIN P-NITROPHENYL ESTER Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

(+)-Biotin 4-nitrophenyl ester may be used in the preparation of biotin tagged ARC (adenosine-oligoarginine conjugate) derivative during cellular protein uptake studies. It may also be used to prepare biotinylated quinazoline derivatives, which shows inhibitory activities against VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinase. (+)-Biotin 4-nitrophenyl ester undergoes hydrolysis in the presence of Na[¹⁷O]H to form [¹⁷O₂]biotin, which can be used in solid-state ¹⁷O NMR spectroscopic experiments to analyze large protein-ligand complexes.

Uses

For research use only. Not for use in diagnostic procedures.
Brain natriuretic peptide EIA Kit has been used to measure brain natriuretic peptide (BNP) secreted in human neonatal ventricular cardiomyocyte culture.

General Description

The BNP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting BNP peptide based on the principle of Competitive Enzyme Immunoassay.

reaction suitability

reaction type: Biotinylations

Biochem/physiol Actions

Brain natriuretic peptide (BNP) expressed in mammalian brain and atrial natriuretic peptide (ANP) facilitates various physiological functions including regulation of blood pressure and cardiac remodeling. BNP acts as a potential biomarker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular (LV) dysfunction. Elevated expression of BNP is observed in acute myocardial infarction (AMI) patients. BNP is also implicated in several biological functions such as diuresis, natriureis, hypotensive action and inhibition of aldosterone secretion.

Purification Methods

The ester has been recrystallised by dissolving 2g in 95% EtOH (30mL), heated to dissolve, then cooled in an ice-water bath. The crystals are collected, washed with ice-cold 95% EtOH (5mL) and dried over P2O5. The RF on silica plates (CHCl3/MeOH 19:1) is 0.19 [Bodanszky & Fagan J Am Chem Soc 99 235 1977].

Description

B-type Natriuretic Peptide Recombinant Human produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 32 amino acids and having a molecular mass of 3,500 Dalton. NPPB is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

Natriuretic Peptide Precursor B acts as a cardiac hormone with a variety of biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. Helps restore the body's salt and water balance. Improves heart function.

D-BIOTIN P-NITROPHENYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from D-BIOTIN P-NITROPHENYL ESTER manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: D-BIOTIN P-NITROPHENYL ESTER 33755-53-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-15

Zhuozhou Wenxi import and Export Co., Ltd

Product: BNP 33755-53-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: BNP 33755-53-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

33755-53-2, D-BIOTIN P-NITROPHENYL ESTERRelated Search:

ISOPROPYLUREA 6-Mercaptohexan-1-ol 4-NITROPHENYL CAPRYLATE 4-NITROPHENYL ACETATE 4-methylimidazolidin-2-one 1,3-DIETHYLUREA 1-N-HEPTYLOXY-4-NITROBENZENE 4-BUTOXYANILINE 4-N-BUTOXYNITROBENZENE 3-aminopropanethiol 7-Aminoheptanoic acid N-BUTYL METHYL SULFIDE 4-Nitrophenol PHENYL VALERATE Propyl sulfide 4-Nitrophenyl formate AMYL METHYL SULFIDE D-BIOTIN P-NITROPHENYL ESTER

PBNP

4-NITROPHENYL (+)-BIOTINATE

BIOTIN P-NITROPHENYL ESTER

BIOTIN-ONP

BNP

D-BIOTIN P-NITROPHENYL ESTER

BNP d-Biotin p-nitrophenyl ester

D-(+)-Biotin 4-nitrophenyl ester

BIOTIN-ONP D-Biotin p-nitrophenyl ester

biotinyl-4-nitrophenyl ester

Human B-type Natriuretic Protein

4-Nitrophenyl (+)-biotinate, d-Biotin p-nitrophenyl ester, BNP

1,1'-Binaphthyl-2,2'-diyl phosphate

4-Hydroxy-3,5-dioxa-4-phospha(V)-3H-cyclohepta[2,1-a:3,4-a']dinaphthalene-4-one

4-Hydroxy-4-oxodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin

4-Hydroxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-one

Phosphoric acid 1,1'-binaphthalene-2,2'-diyl ester

(4-nitrophenyl) 5-[(3aR,6S,6aS)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl]pentanoate

5-[(3aR,6S,6aS)-2-keto-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl]valeric acid (4-nitrophenyl) ester

Biotin π-nitrophenyl ester

Monoclonal Anti-NPPB antibody produced in mouse

(+)-Biotin 4-nitrophenyl ester 98%

BNP, D-Biotin 4-nitrophenyl ester

4-Nitrophenyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate

Biotinp-nitrophenyl ester≥ 99% (HPLC)

Biotin-ONp Novabiochem

(+)-Biotin4-NitrophenylEster&gt

(+)-Biotin-ONP

(+)-Biotin 4-nitrophenyl ester, 98%,

(+)-Biotin 4-Nitrophenyl Ester

Brain Natriuretic Peptide EIA Kit

33755-53-2

Chiral Building Blocks

Asymmetric Synthesis

Complex Molecules

cytokine

Biotin