Tetrahydrothiophen-3-one

Product Name: Tetrahydrothiophen-3-one
CAS No.: 1003-04-9
Chemical Name: Tetrahydrothiophen-3-one
Synonyms: dihydrothiophen-3(2h)-one;Dihydro-3-(2H)-thiophenone;4,5-DIHYDRO-3(2H)-THIOPHENONE;TETRAHYDROTHIOPHENE-3-ONE;FEMA 3266;Tetrahydro-thienone;3-thiolanone;Thiolan-3-one;3-THIOPHANONE;Thiolane-3-one
CBNumber: CB8423034
Molecular Formula: C4H6OS
Formula Weight: 102.15
MOL File: 1003-04-9.mol

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Tetrahydrothiophen-3-one Property

Boiling point:: 175 °C(lit.)
Density: 1.194 g/mL at 25 °C(lit.)
vapor density: >1 (vs air)
refractive index: n20/D 1.528(lit.)
FEMA: 3266 | 4,5-DIHYDRO-3(2H)THIOPHENONE
Flash point:: 171 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in DMSO
form: Liquid
Specific Gravity: 1.194
color: Colorless to pale yellow
Odor: at 0.10 % in dipropylene glycol. garlic meaty green vegetables clams buttery
Odor Type: alliaceous
biological source: synthetic
JECFA Number: 498
BRN: 105201
Major Application: flavors and fragrances
InChI: 1S/C4H6OS/c5-4-1-2-6-3-4/h1-3H2
InChIKey: DSXFPRKPFJRPIB-UHFFFAOYSA-N
SMILES: O=C1CCSC1
LogP: -0.29
CAS DataBase Reference: 1003-04-9(CAS DataBase Reference)
NIST Chemistry Reference: Dihydro-3-(2H)-thiophenone(1003-04-9)
EPA Substance Registry System: 3(2H)-Thiophenone, dihydro- (1003-04-9)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-36/37/39
RIDADR: UN 3334
WGK Germany: 3
F: 8-13
Hazard Note: Irritant
TSCA: TSCA listed
HS Code: 29349990
Storage Class: 10 - Combustible liquids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: W326607
Product name: 4,5-Dihydro-3(2H)-thiophenone
Purity: ≥98%, FG
Packaging: 1 unit
Price: $56.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: W326607
Product name: 4,5-Dihydro-3(2H)-thiophenone
Purity: ≥98%, FG
Packaging: 1 unit
Price: $56.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: W326607
Product name: 4,5-Dihydro-3(2H)-thiophenone
Purity: ≥98%, FG
Packaging: 250g
Price: $769
Updated: 2025/07/31

Sigma-Aldrich

Product number: W326607
Product name: 4,5-Dihydro-3(2H)-thiophenone
Purity: ≥98%, FG
Packaging: 1kg
Price: $2800
Updated: 2025/07/31

Sigma-Aldrich

Product number: 264784
Product name: 4,5-Dihydro-3(2H)-thiophenone
Purity: 98%
Packaging: 25g
Price: $18.25
Updated: 2025/07/31

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Tetrahydrothiophen-3-one Chemical Properties,Usage,Production

Description

Tetrahydro-thiophene-3-one is a heterocyclic nonaromatic ketone. It has a garlic meaty, green vegetable, buttery odor. It is present in cooked beef, coffee, roast filbert, and roasted peanut.
Tetrahydro-thiophene-3-one is used as a food flavoring agent. It is also a valuable organic substance key that opens the synthetic access to numerous derivatives of thiophene.

Chemical Properties

Clear light yellow liquid

Chemical Properties

4,5-Dihydro-3-(2H)thiophenone has a garlic meaty, green vegetable, buttery odor. It is a heterocyclic nonaromatic ketone.

Occurrence

Reported found in cooked beef, coffee, roasted filberts and roasted peanuts.

Uses

4,5-Dihydro-3(2H)-thiophenone is a volatile organic sulfur compound (VOSC) produced by basidiomycetous yeasts.

Uses

Used for blending soft drinks, beverage, meat products, confectionery, and milk product flavors.

Preparation

From 4-methoxycarboxyl-3-oxothiophane treated with 10% sulfuric acid.

Taste threshold values

Taste characteristics at 15 ppm: onion, garlic, cooked meaty with vegetables nuances

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 2229, 1946 DOI: 10.1021/ja01215a034

References

[1] George A. Burdock (2010) Fenaroli's Handbook of Flavor Ingredients, Sixth Edition
[2] https://pubchem.ncbi.nlm.nih.gov
[3] Patent 0127121 A1: Process for the preparation of tetrahydro-thiophen-3-one

Tetrahydrothiophen-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

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Tetrahydrothiophen-3-one Suppliers

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View Lastest Price from Tetrahydrothiophen-3-one manufacturers

Shaanxi Didu New Materials Co. Ltd

Product: Tetrahydrothiophen-3-one 1003-04-9
Price: US $1.50/g
Min. Order: 1g
Purity: 99.0% Min
Supply Ability: 100 Tons
Release date: 2025-09-20

HANGZHOU HAILAN CHEMICAL CO.,LTD.

Product: Tetrahydrothiophen-3-one 1003-04-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 20tons
Release date: 2025-09-02

Shaanxi Dideu New Materials Co. Ltd

Product: Tetrahydrothiophen-3-one 1003-04-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 10000KGS
Release date: 2025-06-26

1003-04-9, Tetrahydrothiophen-3-oneRelated Search:

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Tetrahydro-thienone

4,5-Dihydro-3(2H)-thiophenone≥ 99% (GC)

3-thiolanone

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3’-Tetrahydrothiophenone

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etrahydrothiophen-3-one

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High Quality Tetrahydrothiophen-3-One CAS 1003-04-9

High purity CAS 1003-04-9 Tetrahydrothiophen-3-one in stock

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