ChemicalBook > CAS DataBase List > 1-Tetralone

1-Tetralone

Product Name
1-Tetralone
CAS No.
529-34-0
Chemical Name
1-Tetralone
Synonyms
tetralone;3,4-Dihydronaphthalen-1(2H)-one;α-Tetralone;A-TETRALONE;3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE;ALPHA-TETRALONE;Tetralin-1-one;1(2H)-Naphthalenone;2,3,4-Trihydronaphthalen-1-one;3,4-dihydro-1(2h)-naphthalenon
CBNumber
CB7357499
Molecular Formula
C10H10O
Formula Weight
146.19
MOL File
529-34-0.mol
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1-Tetralone Property

Melting point:
2-7 °C(lit.)
Boiling point:
113-116 °C6 mm Hg(lit.)
Density 
1.099 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.568(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Chloroform, Ethyl Acetate (Slightly)
form 
Liquid
color 
brown
Water Solubility 
insoluble
BRN 
607374
InChIKey
XHLHPRDBBAGVEG-UHFFFAOYSA-N
CAS DataBase Reference
529-34-0(CAS DataBase Reference)
NIST Chemistry Reference
1(2H)-Naphthalenone, 3,4-dihydro-(529-34-0)
EPA Substance Registry System
1,2,3,4-Tetrahydronaphthalen-1-one (529-34-0)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-20/22-20/21/22
Safety Statements 
23-24/25-36
WGK Germany 
3
RTECS 
QK4375000
TSCA 
Yes
HS Code 
29143900
Hazardous Substances Data
529-34-0(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 810 mg/kg LD50 dermal Rabbit > 2200 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T19003
Product name
α-Tetralone
Purity
97%
Packaging
5g
Price
$30.8
Updated
2024/03/01
Sigma-Aldrich
Product number
8.08203
Product name
1,2,3,4-Tetrahydro-1-naphthalenone
Purity
for synthesis
Packaging
100mL
Price
$85.6
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR3081
Product name
Phenylbutyrate Related Compound B
Purity
pharmaceutical secondary standard, certified reference material
Packaging
200MG
Price
$576
Updated
2024/03/01
Sigma-Aldrich
Product number
8.08203
Product name
1,2,3,4-Tetrahydro-1-naphthalenone
Purity
for synthesis
Packaging
250ML
Price
$167
Updated
2024/03/01
Sigma-Aldrich
Product number
1614556
Product name
Phenylbutyrate Related Compound B
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
100mg
Price
$905
Updated
2024/03/01
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1-Tetralone Chemical Properties,Usage,Production

Chemical Properties

Clear amber to brown oily liquid

Uses

1-Tetralone is a reagent used in the synthesis of amino-pyrazolopyridines with anti-NF-κB and pro-apoptotic potential.

Synthesis Reference(s)

Tetrahedron Letters, 32, p. 4291, 1991 DOI: 10.1016/S0040-4039(00)92151-8

Purification Methods

Check the IR first. Purify α-tetralone by dissolving 20mL in Et2O (200mL), washing with H2O (100mL), 5% aqueous NaOH (100mL), H2O (100mL), 3% aqueous AcOH (100mL), 5% NaHCO3 (100mL) then H2O (100mL) and dry the ethereal layer over MgSO4. Filter, evaporate and fractionate the residue through a 6in Vigreux column (p 11) under reduced pressure to give a colourless oil (~17g) with b 90-91o/0.50.7mm. [Snyder & Werber Org Synth Coll Vol III 798 1955.] It has also been fractionated through a 0.5metre packed column with a heated jacket under reflux using a partial take-off head. It has max 247.5 and 290nm (hexane). The phenylhydrazone has m 83o. The 2,4,6-trinitrophenylhydrazone has m 247.5-248o (from EtOH). [Olson & Bader Org Synth Coll Vol IV 898 1963, Beilstein 7 H 370, 7 III 1416, 7 IV 1015.]

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1-Tetralone Suppliers

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16684
Advantage
50
Jinan Dexinjia Bio&Tech Co., Ltd
Tel
0531-82375886 13001715031
Fax
0531-82375893
Email
3517280075@qq.com
Country
China
ProdList
1306
Advantage
58
Zhejiang zetian fine chemical co. LTD
Tel
0571-87322520 18957127338
Email
June@zetchem.com
Country
China
ProdList
397
Advantage
58
Zhejiang Karry Pharmachem Co., Ltd.
Tel
19157666807
Email
info@karrypharma.com
Country
China
ProdList
37
Advantage
58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd.
Tel
0513-82104991 18912868361
Fax
QQ1907456386
Email
sales2@btcpharm.com
Country
China
ProdList
1329
Advantage
58
BTC Pharmaceutical CO. Ltd
Tel
0513-0513-68015397 18862996710
Fax
0513-68015394
Email
sales12@btcpharm.com
Country
China
ProdList
689
Advantage
55
Qingdao Lianli Longmen Technology Co., Ltd
Tel
17661777413 17661777413
Email
1904350824@qq.com
Country
China
ProdList
41
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
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View Lastest Price from 1-Tetralone manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
1-Tetralone 529-34-0
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-22
hebei hongtan Biotechnology Co., Ltd
Product
1-Tetralone 529-34-0
Price
US $280.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-05-13
Hebei Yanxi Chemical Co., Ltd.
Product
1-Tetralone 529-34-0
Price
US $50.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2023-10-20

529-34-0, 1-TetraloneRelated Search:


  • KETOTETRAHYDRONAPHTHALENE
  • A-TETRALONE
  • 1,2,3,4-TETRAHYDRO-1-NAPHTHALENONE
  • 1-TETRALONE
  • 3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE
  • 3,4-DIHYDRO-1-(2H)NAPHTHALENEONE
  • 3,4-DIHYDRO-1(2H)-NAPHTHALENONE
  • ALPHA-TETRALONE
  • 1(2H)-Naphthalenone
  • 1,2,3,4-Tetrahydro-1-oxonaphthalene
  • 1-Tetralone,97%
  • 1(2H)-Naphthalenone, 3,4-dihydro-
  • 3,4-Dihydronaphthalen-1(2H)-one
  • 2,3,4-Trihydronaphthalen-1-one
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  • 1,2,3,4-TETRAHYDRO-1-NAPHTHALENONE FOR S
  • alpha-Tetralone 97%
  • 1-4 hydrogen naphthalene ketone
  • Phenylbutyrate Related CoMpound B
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  • 1,2,3,4-Tetrahydro-1-naphthalenone for synthesis
  • 1,2,3,4-Tetrahydronaphthalen-1-One OR Alpha Tetralone
  • 1,2,3,4-Tetrahydronaphthalen-1-one
  • 1-Oxo-1,2,3,4-tetrahydronaphthalene
  • 1-Oxote-trahydronaphthalene
  • 1-Oxotetralin
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  • Phenylbutyrate Related Compound 1 (1-Tetralone)
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  • Tetralin-1-one
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  • α-Tetralone/1-Tetralone
  • α-Tetralone
  • 1-Tetralone 1,2,3,4-Tetrahydro-1-naphthalenone
  • Phenylbutyrate Related Compound B (3,4-dihydronaphthalen-1(2H)-one) (1614556)
  • 3,4-dihydronaphthalen-1(2H)-one (α-tetralone)
  • Sodium Phenylbutyrate EP Impurity B
  • 1-Tetralone or Alpha Tetralone