ChemicalBook > CAS DataBase List > 3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE

3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE

Product Name
3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
CAS No.
633283-39-3
Chemical Name
3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
Synonyms
VU 10010;3-Amino-N-(4-chlorobenzyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide;3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxylic acid 4-chloro-benzylamide;3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE;Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-[(4-chlorophenyl)methyl]-4,6-dimethyl-;hippocampus,synapses,acetylcholine,allosteric,excitatory,transmission,mAChR,Muscarinic acetylcholine receptor,carbachol,Inhibitor,inhibit,VU10010,proteins,depression,VU-10010
CBNumber
CB12448258
Molecular Formula
C17H16ClN3OS
Formula Weight
345.85
MOL File
633283-39-3.mol
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3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE Property

storage temp. 
Store at +4°C
solubility 
Soluble in DMSO > 10 mM
form 
Powder
color 
White to off-white
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Safety

Hazard Codes 
Xn
Risk Statements 
22-41
Safety Statements 
26-39
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris
Product number
3141
Product name
VU10010
Purity
≥99%(HPLC)
Packaging
10
Price
$197
Updated
2021/12/16
Tocris
Product number
3141
Product name
VU10010
Purity
≥99%(HPLC)
Packaging
50
Price
$780
Updated
2021/12/16
Usbiological
Product number
257070
Product name
VU 10010
Packaging
10mg
Price
$446
Updated
2021/12/16
TRC
Product number
A603825
Product name
3-Amino-N-[(4-chlorophenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
Packaging
10mg
Price
$130
Updated
2021/12/16
ApexBio Technology
Product number
B7285
Product name
VU10010
Packaging
10mg
Price
$297
Updated
2021/12/16
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3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE Chemical Properties,Usage,Production

Uses

This compound acts as a selective allosteric M4 (Muscarinic Acetylcholine Receptor) agonist.

Biological Activity

Selective allosteric potentiator of M 4 acetylcholine receptors (EC 50 values are 33 and 0.7 nM for ACh in the absence and presence of VU10010 espectively). Binds to an allosteric site on the receptor increasing affinity for ACh and coupling to G-proteins.

storage

Store at +4°C

3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE Suppliers

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633283-39-3, 3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDERelated Search:


  • 3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
  • VU 10010
  • Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-[(4-chlorophenyl)methyl]-4,6-dimethyl-
  • 3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxylic acid 4-chloro-benzylamide
  • 3-Amino-N-(4-chlorobenzyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
  • hippocampus,synapses,acetylcholine,allosteric,excitatory,transmission,mAChR,Muscarinic acetylcholine receptor,carbachol,Inhibitor,inhibit,VU10010,proteins,depression,VU-10010
  • 633283-39-3