ChemicalBook > CAS DataBase List > 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE
1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE
- Product Name
- 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE
- CAS No.
- 301648-08-8
- Chemical Name
- 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE
- Synonyms
- UCB 35625;1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE
- CBNumber
- CB12453443
- Molecular Formula
- C30H37Cl2N2O2.I
- Formula Weight
- 655.44
- MOL File
- 301648-08-8.mol
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1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Property
- storage temp.
- Store at +4°C
- solubility
- <32.77mg/ml in ethanol; <65.54mg/ml in DMSO
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N-Bromosuccinimide Price
Tocris
- Product number
- 2757
- Product name
- UCB35625
- Purity
- ≥98%(HPLC)
- Packaging
- 1
- Price
- $147
- Updated
- 2021/12/16
Tocris
- Product number
- 2757
- Product name
- UCB35625
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $311
- Updated
- 2021/12/16
Usbiological
- Product number
- 257011
- Product name
- UCB 35625
- Packaging
- 1mg
- Price
- $380
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0001210
- Product name
- UCB 35625
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.97
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7176
- Product name
- UCB35625
- Packaging
- 1mg
- Price
- $218
- Updated
- 2021/12/16
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1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Chemical Properties,Usage,Production
Uses
UCB 35625 is an antagonist of CCR1, which are receptors prevalent in chronic inflammatory processes. UCB 35625 displays antiarthritic activity and is also a selective antagonist of CCR3.
Biological Activity
Potent chemokine CCR1 and CCR3 receptor antagonist. Inhibits MIP-1 α -induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants (IC 50 values are 9.57 and 93.8 nM respectively). Antagonizes CCR3-mediated entry of HIV-1 isolate 89.6 into NP-2 cells (IC 50 = 57 nM). Isomer of J 113863 (1,4-cis-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidiniumiodide ).
1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Suppliers
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301648-08-8, 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDERelated Search:
TRIMETHYLNONYLAMMONIUMIODIDE
ALLYLTRIETHYLAMMONIUM IODIDE
XANTHENE-9-CARBOXAMIDE
XANTHENE-9-METHYLAMINE
1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE