1H-INDOLE-3-CARBOXYLIC ACID,6-BROMO-,METHYL ESTER
- Product Name
- 1H-INDOLE-3-CARBOXYLIC ACID,6-BROMO-,METHYL ESTER
- CAS No.
- 868656-97-7
- Chemical Name
- 1H-INDOLE-3-CARBOXYLIC ACID,6-BROMO-,METHYL ESTER
- Synonyms
- Methyl 6-Bromoindole-3-carboxylate;6-Bromo-1H-indole-3-Carbocylic acid methyl ester;6-Bromo-1H-indole-3-carboxylic acid methyl ester;1H-INDOLE-3-CARBOXYLIC ACID,6-BROMO-,METHYL ESTER;H-Indole-3-carboxylic acid, 6-bromo-, methyl ester;1H-Indole-3-Carboxylic Acid,6-Bromo-,Methyl Ester, 10 mM in DMSO
- CBNumber
- CB12457926
- Molecular Formula
- C10H8BrNO2
- Formula Weight
- 254.08
- MOL File
- 868656-97-7.mol
1H-INDOLE-3-CARBOXYLIC ACID,6-BROMO-,METHYL ESTER Property
- Boiling point:
- 386.2±22.0 °C(Predicted)
- Density
- 1.629±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- Solid
- pka
- 14.49±0.30(Predicted)
- color
- Off-white to light yellow
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 3663AC
- Product name
- Methyl6-bromo-1H-indole-3-carboxylate
- Packaging
- 1g
- Price
- $177
- Updated
- 2021/12/16
- Product number
- OR471662
- Product name
- Methyl6-bromoindole-3-carboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $225
- Updated
- 2021/12/16
- Product number
- HCH0063593
- Product name
- 1H-INDOLE-3-CARBOXYLIC ACID,6-BROMO-,METHYL ESTER
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.8
- Updated
- 2021/12/16
- Product number
- OR471662
- Product name
- Methyl6-bromoindole-3-carboxylate
- Purity
- 97%
- Packaging
- 5g
- Price
- $670
- Updated
- 2021/12/16
- Product number
- 3663AC
- Product name
- Methyl6-bromo-1H-indole-3-carboxylate
- Packaging
- 25g
- Price
- $1184
- Updated
- 2021/12/16
1H-INDOLE-3-CARBOXYLIC ACID,6-BROMO-,METHYL ESTER Chemical Properties,Usage,Production
Uses
Methyl 6-bromo-1H-indole-3-carboxylate is a marine-derived natural product with antitumor activity. Methyl 6-bromo-1H-indole-3-carboxylate showed growth inhibition against Staphylococcus epidermidis, exhibiting weak or moderate minimum inhibitory concentrations (MICs)[1].
Synthesis
101774-27-0
18107-18-1
868656-97-7
Intermediate Preparation: methyl 6-bromo-1H-indole-3-carboxylate; (Trimethylsilyl)diazomethane (2.0 M hexane solution, ca. 9 mL) was added dropwise to a solution of 6-bromo-1H-indole-3-carboxylic acid (960 mg, 4.00 mmol) in methanol (9.5 mL) at room temperature, with the dropwise addition time being controlled to be within 2 minutes. After the reaction mixture took on a yellow color, it was concentrated under reduced pressure. The concentrated residue was redissolved in methanol and concentrated again under reduced pressure. This dissolution-concentration process was repeated several times to give the title compound methyl 6-bromo-1H-indole-3-carboxylate as a solid product in 100% yield.ES/MS m/e: 256.0 (M+2).
References
[1] Investigation of brominated tryptophan alkaloids from two thorectidae sponges: Thorectandra and Smenospongia
1H-INDOLE-3-CARBOXYLIC ACID,6-BROMO-,METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-INDOLE-3-CARBOXYLIC ACID,6-BROMO-,METHYL ESTER manufacturers
- Product
- 1H-INDOLE-3-CARBOXYLIC ACID,6-BROMO-,METHYL ESTER 868656-97-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-10
- Product
- 1H-INDOLE-3-CARBOXYLIC ACID,6-BROMO-,METHYL ESTER 868656-97-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-08