5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-OL
- Product Name
- 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-OL
- CAS No.
- 33781-38-3
- Chemical Name
- 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-OL
- Synonyms
- 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-OL
- CBNumber
- CB12458266
- Molecular Formula
- C9H9ClO
- Formula Weight
- 168.62
- MOL File
- 33781-38-3.mol
5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-OL Property
- Boiling point:
- 292.7±35.0 °C(Predicted)
- Density
- 1.322±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.02±0.20(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2906290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C433248
- Product name
- 5-Chloro-2,3-dihydro-1H-inden-1-ol
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 3977AB
- Product name
- 5-Chloro-2,3-dihydro-1H-inden-1-ol
- Packaging
- 250mg
- Price
- $158
- Updated
- 2021/12/16
- Product number
- HCH0367190
- Product name
- 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-OL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.33
- Updated
- 2021/12/16
- Product number
- A280702
- Product name
- 5-Chloro-2,3-dihydro-1H-inden-1-ol
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $9
- Updated
- 2021/12/16
- Product number
- A280702
- Product name
- 5-Chloro-2,3-dihydro-1H-inden-1-ol
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $16
- Updated
- 2021/12/16
5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-OL Chemical Properties,Usage,Production
Synthesis
42348-86-7
33781-38-3
To a solution of 5-chloro-1-indanone (500 g, 301.2 mmol) in tetrahydrofuran (THF, 500 mL), an aqueous solution (100 mL) of sodium borohydride (23.0 g, 602.4 mmol) was slowly added dropwise at a controlled temperature of between 0 °C and 100 °C for 1 hour. The reaction mixture was stirred at room temperature for 12 hours. After completion of the reaction, the reaction was quenched with water (500 mL) and extracted with ethyl acetate (3 x 1500 mL). The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford a racemic mixture of 5-chloro-2,3-dihydro-1H-inden-1-ol (48.0 g, 94.8% yield), which can be used directly in the next step of the reaction without further purification.
References
[1] Journal of the American Chemical Society, 2005, vol. 127, # 30, p. 10482 - 10483
[2] Patent: WO2017/147410, 2017, A1. Location in patent: Page/Page column 134; 135
[3] Bulletin de la Societe Chimique de France, 1973, p. 3096 - 3099
[4] Journal of Medicinal Chemistry, 2005, vol. 48, # 5, p. 1563 - 1575
[5] Journal of Medicinal Chemistry, 2005, vol. 48, # 6, p. 1796 - 1805
5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-OL Preparation Products And Raw materials
Raw materials
Preparation Products
5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-OL Suppliers
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
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- Fax
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- info@synthonix.com
- Country
- United States
- ProdList
- 6872
- Advantage
- 58
- Tel
- --
- Fax
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- sales@matrixscientific.com
- Country
- United States
- ProdList
- 6632
- Advantage
- 80
View Lastest Price from 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-OL manufacturers
- Product
- 5-CHLORO-2,3-DIHYDRO-1H-INDEN-1-OL 33781-38-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-15