2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE

Product Name: 2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE
CAS No.: 885618-31-5
Chemical Name: 2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE
Synonyms: 129558;2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE;2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE-5;2-chloro-4-(Morpholin-4-yl)thieno[3,2-d]pyriMidine-6-carbaldehyde;2-chloro-4-(4-morpholinyl)-Thieno[3,2-d]pyrimidine-6-carboxaldehyde;2-Chloro-4-(Morpholin-4-yl)thieno[3,2-d]pyriMidine-6-carboxaldehyde;Thieno[3,2-d]pyriMidine-6-carboxaldehyde, 2-chloro-4-(4-Morpholinyl)-
CBNumber: CB12460546
Molecular Formula: C11H10ClN3O2S
Formula Weight: 283.73
MOL File: 885618-31-5.mol

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2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE Property

Density: 1.522±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 2.91±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: C360490
Product name: 2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde
Packaging: 100mg
Price: $170
Updated: 2021/12/16

AK Scientific

Product number: W9116
Product name: 2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde
Packaging: 100mg
Price: $217
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC154363
Product name: 2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde
Packaging: 250mg
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC154363
Product name: 2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde
Packaging: 50mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC154363
Product name: 2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde
Packaging: 100mg
Price: $160
Updated: 2021/12/16

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2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE Chemical Properties,Usage,Production

Synthesis

68-12-2

885618-31-5

The general procedure for the synthesis of 2-chloro-4-(4-morpholino)-thieno[3,2-d]pyrimidine-6-carboxaldehyde from N,N-dimethylformamide is as follows: referring to Example 3, a solution of 2-chloro-4-morpholino-4-yl-thieno[3,2-d]pyrimidine (65) (1.75 g, 6.85 mmol) in anhydrous THF (40 mL) was stirred at -78 °C. A hexane solution of 2.5 M n-butyllithium (3.3 mL, 1.2 equiv) was slowly added. The reaction mixture was continued to be stirred at -78 °C for 1 h. Anhydrous N,N-dimethylformamide (796 μL, 1.5 eq.) was added. After keeping the reaction at -78 °C for 1 h, the reaction was slowly warmed up to room temperature. Stirring was continued at room temperature for 2 h. Upon completion of the reaction, the mixture was poured into ice/water and a yellow precipitate precipitated. The precipitate was collected by filtration and air dried to afford the target product 2-chloro-4-(4-morpholino)-thieno[3,2-d]pyrimidine-6-carboxaldehyde (1.50 g, 77% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 3.76 (4H, t, J = 4.9 Hz), 3.95 (4H, t, J = 4.9 Hz), 8.28 (1H, s), 10.20 (1H, s).

References

[1] Patent: WO2006/46031, 2006, A1. Location in patent: Page/Page column 30
[2] Patent: US2008/76768, 2008, A1. Location in patent: Page/Page column 7
[3] Patent: US2008/76758, 2008, A1. Location in patent: Page/Page column 73
[4] Patent: WO2007/122410, 2007, A1. Location in patent: Page/Page column 63
[5] Patent: WO2007/127183, 2007, A1. Location in patent: Page/Page column 136

2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE Suppliers

China 52 Germany 1 India 2 United Kingdom 1 United States 5 Global 61

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

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View Lastest Price from 2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE manufacturers

Career Henan Chemical Co

Product: 2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE 885618-31-5
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

885618-31-5, 2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDERelated Search:

Morpholinazole

2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE

2-chloro-4-(Morpholin-4-yl)thieno[3,2-d]pyriMidine-6-carbaldehyde

Thieno[3,2-d]pyriMidine-6-carboxaldehyde, 2-chloro-4-(4-Morpholinyl)-

2-Chloro-4-(Morpholin-4-yl)thieno[3,2-d]pyriMidine-6-carboxaldehyde

2-CHLORO-4-MORPHOLINOTHIENO[3,2-D]PYRIMIDINE-6-CARBALDEHYDE-5

2-chloro-4-(4-morpholinyl)-Thieno[3,2-d]pyrimidine-6-carboxaldehyde

129558

885618-31-5

Heterocycle-Pyrimidine series