4-Ethoxy-2-pyridinecarboxylic acid ethyl ester
- Product Name
- 4-Ethoxy-2-pyridinecarboxylic acid ethyl ester
- CAS No.
- 71777-70-3
- Chemical Name
- 4-Ethoxy-2-pyridinecarboxylic acid ethyl ester
- Synonyms
- Ethyl 4-ethoxypicolinate;Ethyl 4-ethoxy-2-pyridinecarboxylate;ethyl 4-ethoxypyridine-2-carboxylate;4-Ethoxypyridine-2-carboxylic acid ethyl ester;4-Ethoxy-2-pyridinecarboxylic acid ethyl ester;2-Pyridinecarboxylic acid, 4-ethoxy-, ethyl ester
- CBNumber
- CB12470347
- Molecular Formula
- C10H13NO3
- Formula Weight
- 195.22
- MOL File
- 71777-70-3.mol
4-Ethoxy-2-pyridinecarboxylic acid ethyl ester Property
- Density
- 1.099
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- Light yellow to yellow Solid-liquid mixture
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 1146AC
- Product name
- Ethyl4-ethoxypicolinate
- Packaging
- 250mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- CHM0392495
- Product name
- ETHYL-4-ETHOXYPICOLINATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.76
- Updated
- 2021/12/16
- Product number
- A314941
- Product name
- Ethyl4-ethoxypicolinate
- Purity
- 97%
- Packaging
- 100mg
- Price
- $63
- Updated
- 2021/12/16
- Product number
- A314941
- Product name
- Ethyl4-ethoxypicolinate
- Purity
- 97%
- Packaging
- 250mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- CM128820
- Product name
- ethyl4-ethoxypicolinate
- Purity
- 97%
- Packaging
- 1g
- Price
- $269
- Updated
- 2021/12/16
4-Ethoxy-2-pyridinecarboxylic acid ethyl ester Chemical Properties,Usage,Production
Synthesis
5470-22-4
64-17-5
71777-70-3
General procedure for the synthesis of ethyl 4-ethoxy-2-pyridinecarboxylate from 4-chloropyridine-2-carboxylic acid and ethanol: 4-chloropyridine-2-carboxylic acid (3.0 g, 19.04 mmol) was dissolved in ethanol (100 mL) and concentrated sulfuric acid (5 mL) was added as a catalyst. The reaction mixture was stirred under reflux conditions for 48 hours. After completion of the reaction, the mixture was cooled to room temperature and neutralized with 1N NaOH solution to pH 8~9. Subsequently, the reaction mixture was extracted with dichloromethane (3 x 100 mL), the organic phases were combined and concentrated to afford ethyl 4-ethoxy-2-pyridinecarboxylate (3.44 g, 93% yield).
References
[1] Patent: WO2007/16525, 2007, A2. Location in patent: Page/Page column 54
[2] Patent: US2013/281396, 2013, A1. Location in patent: Paragraph 0319-0320
[3] Patent: WO2013/164769, 2013, A1. Location in patent: Page/Page column 46-47
4-Ethoxy-2-pyridinecarboxylic acid ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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