ChemicalBook > CAS DataBase List > 4-Ethoxy-2-pyridinecarboxylic acid ethyl ester

4-Ethoxy-2-pyridinecarboxylic acid ethyl ester

Product Name
4-Ethoxy-2-pyridinecarboxylic acid ethyl ester
CAS No.
71777-70-3
Chemical Name
4-Ethoxy-2-pyridinecarboxylic acid ethyl ester
Synonyms
Ethyl 4-ethoxypicolinate;Ethyl 4-ethoxy-2-pyridinecarboxylate;ethyl 4-ethoxypyridine-2-carboxylate;4-Ethoxypyridine-2-carboxylic acid ethyl ester;4-Ethoxy-2-pyridinecarboxylic acid ethyl ester;2-Pyridinecarboxylic acid, 4-ethoxy-, ethyl ester
CBNumber
CB12470347
Molecular Formula
C10H13NO3
Formula Weight
195.22
MOL File
71777-70-3.mol
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4-Ethoxy-2-pyridinecarboxylic acid ethyl ester Property

Density 
1.099
storage temp. 
Inert atmosphere,Room Temperature
Appearance
Light yellow to yellow Solid-liquid mixture
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

AK Scientific
Product number
1146AC
Product name
Ethyl4-ethoxypicolinate
Packaging
250mg
Price
$155
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0392495
Product name
ETHYL-4-ETHOXYPICOLINATE
Purity
95.00%
Packaging
5MG
Price
$495.76
Updated
2021/12/16
Ambeed
Product number
A314941
Product name
Ethyl4-ethoxypicolinate
Purity
97%
Packaging
100mg
Price
$63
Updated
2021/12/16
Ambeed
Product number
A314941
Product name
Ethyl4-ethoxypicolinate
Purity
97%
Packaging
250mg
Price
$115
Updated
2021/12/16
Chemenu
Product number
CM128820
Product name
ethyl4-ethoxypicolinate
Purity
97%
Packaging
1g
Price
$269
Updated
2021/12/16
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4-Ethoxy-2-pyridinecarboxylic acid ethyl ester Chemical Properties,Usage,Production

Synthesis

5470-22-4

64-17-5

71777-70-3

General procedure for the synthesis of ethyl 4-ethoxy-2-pyridinecarboxylate from 4-chloropyridine-2-carboxylic acid and ethanol: 4-chloropyridine-2-carboxylic acid (3.0 g, 19.04 mmol) was dissolved in ethanol (100 mL) and concentrated sulfuric acid (5 mL) was added as a catalyst. The reaction mixture was stirred under reflux conditions for 48 hours. After completion of the reaction, the mixture was cooled to room temperature and neutralized with 1N NaOH solution to pH 8~9. Subsequently, the reaction mixture was extracted with dichloromethane (3 x 100 mL), the organic phases were combined and concentrated to afford ethyl 4-ethoxy-2-pyridinecarboxylate (3.44 g, 93% yield).

References

[1] Patent: WO2007/16525, 2007, A2. Location in patent: Page/Page column 54
[2] Patent: US2013/281396, 2013, A1. Location in patent: Paragraph 0319-0320
[3] Patent: WO2013/164769, 2013, A1. Location in patent: Page/Page column 46-47

4-Ethoxy-2-pyridinecarboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Ethoxy-2-pyridinecarboxylic acid ethyl ester Suppliers

JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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86-021-50426522,50426273
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China
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Record Tech (Shanghai) Co., LTD
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86-21-64965863
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183009664@qq.com
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China
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Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.
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022-60116533 13207668525
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saleskc@scipharmacn.com
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China
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SynAsst Chemical.
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021-35122006
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China
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Synchem OHG
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+49 5662 408730
Fax
+49 5662 4087320
Email
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Country
Germany
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Chengdu Firster Pharmaceutical Co., Ltd.
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Shanghai SuperLan Chemcial Technique Centre
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71777-70-3, 4-Ethoxy-2-pyridinecarboxylic acid ethyl esterRelated Search:


  • 4-Ethoxy-2-pyridinecarboxylic acid ethyl ester
  • Ethyl 4-ethoxy-2-pyridinecarboxylate
  • Ethyl 4-ethoxypicolinate
  • 4-Ethoxypyridine-2-carboxylic acid ethyl ester
  • ethyl 4-ethoxypyridine-2-carboxylate
  • 2-Pyridinecarboxylic acid, 4-ethoxy-, ethyl ester
  • 71777-70-3