ChemicalBook > CAS DataBase List > 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea

Product Name
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
CAS No.
839713-36-9
Chemical Name
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
Synonyms
APD125;APD-125;APD 125;Nelotanserin;APD125(Nelotanserin);APD125;APD-125;APD 125;APD125; APD-125; APD 125; NELOTANSERIN;1-[3-(4-bromo-2-methylpyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea;1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea;1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
CBNumber
CB12484964
Molecular Formula
C18H15BrF2N4O2
Formula Weight
437.24
MOL File
839713-36-9.mol
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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Property

Boiling point:
425.9±45.0 °C(Predicted)
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:32.0(Max Conc. mg/mL);73.2(Max Conc. mM)
form 
Solid
pka
12.29±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
N389655
Product name
Nelotanserin
Packaging
5mg
Price
$165
Updated
2021/12/16
TRC
Product number
N389655
Product name
Nelotanserin
Packaging
25mg
Price
$670
Updated
2021/12/16
AK Scientific
Product number
9867CS
Product name
Nelotanserin
Packaging
100mg
Price
$549
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB101032
Product name
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
Packaging
50mg
Price
$231
Updated
2021/12/16
ChemScene
Product number
CS-5984
Product name
Nelotanserin
Purity
99.79%
Packaging
25mg
Price
$250
Updated
2021/12/16
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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Chemical Properties,Usage,Production

Uses

Nelotanserin is a potent selective 5-HT2A inverse agonist, nelotanserin has low nanomolar potency on the 5-HT2A receptor with at least 30- and 5000-fold selectivity compared with 5-HT2C and 5-HT2B receptors.

Definition

ChEBI: Nelotanserin is a member of pyrazoles and a ring assembly.

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Suppliers

China 48 India 2 United Kingdom 1 United States 6 USA 1 Global 58
Carbosynth
Tel
--
Fax
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Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58

839713-36-9, 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)ureaRelated Search:


  • APD125(Nelotanserin)
  • APD 125
  • APD125
  • APD-125
  • APD125;APD-125;APD 125
  • 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
  • Urea, N-[3-(4-broMo-1-Methyl-1H-pyrazol-5-yl)-4-Methoxyphenyl]-N'-(2,4-difluorophenyl)-
  • Nelotanserin
  • 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
  • APD125; APD-125; APD 125; NELOTANSERIN
  • 1-[3-(4-bromo-2-methylpyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
  • 5-HT Receptor,Inhibitor,APD 125,inhibit,APD-125,Nelotanserin,Serotonin Receptor,5-hydroxytryptamine Receptor
  • 839713-36-9