ChemicalBook > CAS DataBase List > 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
- Product Name
- 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
- CAS No.
- 839713-36-9
- Chemical Name
- 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
- Synonyms
- APD125;APD-125;APD 125;Nelotanserin;APD125(Nelotanserin);APD125;APD-125;APD 125;APD125; APD-125; APD 125; NELOTANSERIN;1-[3-(4-bromo-2-methylpyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea;1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea;1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
- CBNumber
- CB12484964
- Molecular Formula
- C18H15BrF2N4O2
- Formula Weight
- 437.24
- MOL File
- 839713-36-9.mol
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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Property
- Boiling point:
- 425.9±45.0 °C(Predicted)
- Density
- 1.55±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:32.0(Max Conc. mg/mL);73.2(Max Conc. mM)
- pka
- 12.29±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
TRC
- Product number
- N389655
- Product name
- Nelotanserin
- Packaging
- 5mg
- Price
- $165
- Updated
- 2021/12/16
TRC
- Product number
- N389655
- Product name
- Nelotanserin
- Packaging
- 25mg
- Price
- $670
- Updated
- 2021/12/16
AK Scientific
- Product number
- 9867CS
- Product name
- Nelotanserin
- Packaging
- 100mg
- Price
- $549
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FB101032
- Product name
- 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
- Packaging
- 50mg
- Price
- $231
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-5984
- Product name
- Nelotanserin
- Purity
- 99.79%
- Packaging
- 25mg
- Price
- $250
- Updated
- 2021/12/16
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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Chemical Properties,Usage,Production
Uses
Nelotanserin is a potent selective 5-HT2A inverse agonist, nelotanserin has low nanomolar potency on the 5-HT2A receptor with at least 30- and 5000-fold selectivity compared with 5-HT2C and 5-HT2B receptors.
Definition
ChEBI: Nelotanserin is a member of pyrazoles and a ring assembly.
1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Preparation Products And Raw materials
Raw materials
Preparation Products
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