ChemicalBook > CAS DataBase List > (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester

(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester

Product Name
(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
CAS No.
147489-06-3
Chemical Name
(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
Synonyms
T-Butyl (3R;t-Butyl (3R,5S);tert-butyl 2-((4R,6S);Pitavastatin Calcium Impurity F;Pivastatin calcium intermediate;5-isopropylidenedioxy-6-heptenoate;-7-[2-cyclopropyl-4-(4-fluorophenyl);pitavastatin intermediate 3R5S isomer;3-dioxane-6-heptene?acid?tert-butyl?ester;quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
CBNumber
CB12485022
Molecular Formula
C32H36FNO4
Formula Weight
517.63
MOL File
147489-06-3.mol
More
Less

(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester Property

Melting point:
105-116 °C(Solv: hexane (110-54-3))
Boiling point:
604.6±55.0 °C(Predicted)
Density 
1.184±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.61±0.50(Predicted)
color 
White to Off-White
CAS DataBase Reference
147489-06-3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B689830
Product name
t-Butyl(3R,5S)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
Packaging
500mg
Price
$195
Updated
2021/12/16
Matrix Scientific
Product number
092059
Product name
t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
Purity
95+%
Packaging
5g
Price
$267
Updated
2021/12/16
Matrix Scientific
Product number
092059
Product name
t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
Purity
95+%
Packaging
10g
Price
$475
Updated
2021/12/16
AK Scientific
Product number
X6293
Product name
(3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-2,2-Dimethyl-1,3-dioxane-6-heptenoicacid1,1-dimethylethylester
Packaging
10g
Price
$609
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0036570
Product name
T-BUTYL (3R,5S)-7-[2-CYCLOPROPYL-4-(4-FLUOROPHENYL)QUINOLIN-3-YL]-3,5-ISOPROPYLIDENEDIOXY-6-HEPTENOATE
Purity
95.00%
Packaging
5G
Price
$909.56
Updated
2021/12/16
More
Less

(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester Chemical Properties,Usage,Production

Uses

t-Butyl (3R,5S)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate is an impurity from the synthesis of HMG-CoA reductase inhibitor Pitavastatin [P531040, (Z)-Pitavastatin Calcium Salt].

(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester Suppliers

China 151 India 4 United States 9 Global 164
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
More
Less

View Lastest Price from (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester 147489-06-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10kg/month
Release date
2022-12-28
Nanjing Fred Technology Co., Ltd
Product
(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester 147489-06-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2024-01-03
Hangzhou ICH Biofarm Co., Ltd
Product
(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester 147489-06-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200
Release date
2023-07-12

147489-06-3, (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl esterRelated Search:

Pitavastatin Impurity 2 Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate Pitavastatin Methyl Ester PITAVASTATIN LACTONE 2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxaldehyde 2-Cyclopropyl-3-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)quinoline (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenenitrile 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol [2-Cyclopropyl-4-(4-fluorophenyl)-quinolin-3-ylmethyl]-triphenyl-phosphonium bromido Tert-buthyl Pitavastatin tert-Butyl (4R-cis)-6-formaldehydel-2,2-dimethyl-1,3-dioxane-4-acetate (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal (3S,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid CalciuM Salt (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid CalciuM Salt 3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline Rosuvastatin calcium Pitavastatin calcium

  • (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
  • tert-Butyl(3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
  • (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluoro?phenyl)3-quinoline-base]-2,2-dimethyl-1,3-dioxane-6-heptene?acid?tert-butyl?ester
  • tert-butyl 2-((4R,6S)
  • pitavastatin intermediate 3R5S isomer
  • 2-[6-[2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetic acid tert-butyl ester
  • 3-dioxane-6-heptene?acid?tert-butyl?ester
  • 6E)-7-[2-cyclopropyl-4-(4-fluoro?phenyl)3-quinoline-base]-2
  • (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-2,2-Dimethyl-1,3-dioxane-6- heptenoic acid,1,1-dimethylethyl ester
  • t-Butyl-(3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
  • t-Bytyl(3R,5S)-7-[2-cyclopropyl-4-(4-fluoropenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
  • (3R,5S,E)-tert-butyl7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate
  • t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-hepte
  • 1,3-Dioxane-4-acetic acid,6-[(1E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-,1,1-dimethylethyl ester,(4R,6S)-
  • -7-[2-cyclopropyl-4-(4-fluorophenyl)
  • quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
  • t-Butyl (3R,5S)
  • t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-he
  • (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4
  • 5-isopropylidenedioxy-6-heptenoate
  • 5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3
  • Pitavastatin Calcium Impurity F
  • T-Butyl (3R
  • (4R,6S)-6-[[(1E)-2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]vinyl]-2,2-dimethyl-1, 3-Dioxane-4-acetic acid tert-butyl ester
  • tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
  • t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-...
  • tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,
  • -Butyl(3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate
  • 1,3-Dioxane-4-acetic acid, 6-[(1E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)- (9CI, ACI)
  • 6-[(1E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-Dioxane-4-acetic acid 1,1-dimethylethyl ester (4R,6S)- (9CI ACI)
  • Pivastatin calcium intermediate
  • 147489-06-3