(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal

Product Name: (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal
CAS No.: 148901-68-2
Chemical Name: (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal
Synonyms: PT-4;(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl;3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal;(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-prope;(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-Quinolinyl-2-propenal;(E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde;(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]prop-2-en-1-al;2-Propenal, 3-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-, (2E)-;(E)-3''-[4-(4''-FLUOROPHENYL)-2-(CYCLOPROPYL)-3-QUINOLINYL]-2-PROPENAL
CBNumber: CB4947383
Molecular Formula: C21H16FNO
Formula Weight: 317.36
MOL File: 148901-68-2.mol

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(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal Property

Melting point:: 136-142 °C
Boiling point:: 491.8±45.0 °C(Predicted)
Density: 1.256±0.06 g/cm3(Predicted)
pka: 3.82±0.50(Predicted)
CAS DataBase Reference: 148901-68-2(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: C998148
Product name: (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal
Packaging: 2.5mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C998148
Product name: (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal
Packaging: 5mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: X6298
Product name: (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal
Packaging: 250mg
Price: $180
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC43192
Product name: (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal
Packaging: 50g
Price: $405
Updated: 2021/12/16

AK Scientific

Product number: X6298
Product name: (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenal
Packaging: 1g
Price: $490
Updated: 2021/12/16

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(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal Chemical Properties,Usage,Production

Synthesis

113832-57-8

121660-37-5

148901-68-2

The general procedure for the synthesis of (E)-3-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]acrolein from the compound (CAS: 113832-57-8) and 2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxaldehyde is as follows: the general procedure is as follows: except for the use of ethylidene cyclohexylamine (1.7 g, 13.8 mmol) in place of the ethylidene tert-butylamine (1.4 g, 14.1 mmol), the operation was the same as in Example 1. A portion of the reaction mixture was poured into 10% (w/v) aqueous acetic acid solution and analyzed by high performance liquid chromatography (HPLC) using the internal standard method. The analytical results showed that (E)-3-[4'-(4"-fluorophenyl)-2'-cyclopropylquinolin-3'-yl]propanal (1.7 g, 5.4 mmol, 78.3% yield) was successfully synthesized.

References

[1] Patent: EP1614682, 2006, A1. Location in patent: Page/Page column 6

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal Preparation Products And Raw materials

Raw materials

Preparation Products

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(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal Suppliers

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View Lastest Price from (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal manufacturers

Hangzhou ICH Biofarm Co., Ltd

Product: (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal 148901-68-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500
Release date: 2023-07-12

Career Henan Chemical Co

Product: (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal 148901-68-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-22

148901-68-2, (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenalRelated Search:

(4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester 3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline 2-Amino-4'-fluorobenzophenone 2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxaldehyde 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol 3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER Methyl 3-cyclopropyl-3-oxopropionate Methyl 4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinecarboxylate Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate Quinclorac Ethoxyquin Quinhydrone Quinolinic acid Isoquinoline Acrolein Pitavastatin (E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-Quinolinyl-2-propenal

PT-4

(E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]prop-2-en-1-al

(E)-3''-[4-(4''-FLUOROPHENYL)-2-(CYCLOPROPYL)-3-QUINOLINYL]-2-PROPENAL

3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal

2-Propenal, 3-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-, (2E)-

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl

(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-prope

148901-68-2

C21H16FNO

Pitavastatin Calcium Intermediates