3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER
- Product Name
- 3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER
- CAS No.
- 24922-02-9
- Chemical Name
- 3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER
- Synonyms
- ETHYL 3-CYCLOPROPYL-3-OXO-PROPANOATE;Ethyl β-oxo-cyclopropanepropionate;Carbethoxymethyl cyclopropyl ketone;10Ethyl 3-cyclopropyl-3-oxopropanoate;Ethyl beta-oxo-Cyclopropane Propionate;β-Oxocyclopropanepropanoic athyl ester;3-Cyclopropyl-3-oxo-propionicethyl ester;Ethyl 3-cyclopropyl-3-oxopropionate, 97%;3-Cyclopropyl-3-oxopropionate ethyl ester;β-Oxocyclopropanepropanoic acid ethyl ester
- CBNumber
- CB5360116
- Molecular Formula
- C8H12O3
- Formula Weight
- 156.18
- MOL File
- 24922-02-9.mol
3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER Property
- Boiling point:
- 73℃/1mm
- Density
- 1.058 g/mL at 25 °C
- refractive index
- n20/D1.449
- Flash point:
- >96℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- 10.61±0.20(Predicted)
- color
- Colourless
- InChI
- InChI=1S/C8H12O3/c1-2-11-8(10)5-7(9)6-3-4-6/h6H,2-5H2,1H3
- InChIKey
- LFSVADABIDBSBV-UHFFFAOYSA-N
- SMILES
- C1(CC1)C(=O)CC(=O)OCC
- CAS DataBase Reference
- 24922-02-9(CAS DataBase Reference)
Safety
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 2918300090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 722464
- Product name
- Ethyl-3-cyclopropyl-3-oxopropionate
- Purity
- 96%
- Packaging
- 5g
- Price
- $25.46
- Updated
- 2025/07/31
- Product number
- 722464
- Product name
- Ethyl-3-cyclopropyl-3-oxopropionate
- Purity
- 96%
- Packaging
- 1g
- Price
- $26.8
- Updated
- 2025/07/31
- Product number
- E1023
- Product name
- Ethyl 3-Cyclopropyl-3-oxopropanoate
- Purity
- min. 97.0 %
- Packaging
- 5G
- Price
- $25
- Updated
- 2025/07/31
- Product number
- E1023
- Product name
- Ethyl 3-Cyclopropyl-3-oxopropanoate
- Purity
- min. 97.0 %
- Packaging
- 25G
- Price
- $76
- Updated
- 2025/07/31
- Product number
- E926328
- Product name
- Ethyl3-cyclopropyl-3-oxopropanoate
- Packaging
- 100g
- Price
- $100
- Updated
- 2021/12/16
3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER Chemical Properties,Usage,Production
Uses
Ethyl 3-cyclopropyl-3-oxopropanoate
Synthesis
6148-64-7
4023-34-1
24922-02-9
Under cooling conditions in an ice bath, monoethyl malonate potassium salt (17.0 g, 0.10 mol) was suspended in ethyl acetate (100 ml) and triethylamine (34.7 ml, 0.25 mol) and magnesium chloride (14.3 g, 0.15 mol) were added sequentially. The resulting mixture was stirred and reacted at 40°C for 20 hours. Cyclopropanecarbonyl chloride (4.30 g, 50.0 mmol) was also taken and dissolved in tetrahydrofuran (50 ml), oxalyl chloride (4.36 ml, 50.0 mmol) and a catalytic amount of N,N-dimethylformamide were added under the cooling of an ice bath, stirred for 1 h. After stirring, it was moved to room temperature and the reaction was continued for 1 h. The reaction was continued at room temperature. Subsequently, the previously prepared malonic acid solution was slowly added to this chloride solution under ice bath cooling and the reaction was stirred at room temperature for 20 hours. After completion of the reaction, the mixture was poured into 10% aqueous citric acid solution (300 ml) and extracted with ethyl acetate (300 ml x 3). The organic layers were combined and washed sequentially with saturated aqueous sodium bicarbonate (500 ml) and brine (300 ml) and dried over anhydrous sodium sulfate. The solvent was concentrated under reduced pressure to give ethyl 3-cyclopropyl-3-carbonyl-propionate 7.26 g (93% yield) as a colorless oil, which was used directly in the next reaction.1H-NMR (400 MHz, CDCl3) δ: 0.94-0.99 (2H, m), 1.10-1.15 (2H, m), 1.28 (3H, t, J=7.08 Hz). 2.01-2.06 (1H, m), 3.57 (2H, s), 4.21 (2H, q, J=7.08Hz).
References
[1] Patent: EP1479681, 2004, A1. Location in patent: Page 59
[2] Patent: US2011/71150, 2011, A1. Location in patent: Page/Page column 31
3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER manufacturers
- Product
- Ethyl 3-cyclopropyl-3-oxopropionate 24922-02-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2024-01-04
- Product
- 3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER 24922-02-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 3-CYCLOPROPYL-3-OXO-PROPIONIC ACID ETHYL ESTER 24922-02-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09