(R)-5-HydroxyMethyl Tolterodine

Product Name: (R)-5-HydroxyMethyl Tolterodine
CAS No.: 207679-81-0
Chemical Name: (R)-5-HydroxyMethyl Tolterodine
Synonyms: Desfesoterodine;5-HMT;Fesoterodine Diol;5-HM;PNU-200577;PNU 200577;Non Sorodine Impurities;Fesoterodine Diol (R)-Isomer;Desfesoterodine, 10 mM in DMSO;(R)-5-Hydroxymethyl tolterodine
CBNumber: CB12485062
Molecular Formula: C22H31NO2
Formula Weight: 341.49
MOL File: 207679-81-0.mol

More

Less

(R)-5-HydroxyMethyl Tolterodine Property

Melting point:: 68-72°C
Boiling point:: 490.7±45.0 °C(Predicted)
Density: 1.060±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 9.61±0.48(Predicted)
color: Off-White to Pale Yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H360May damage fertility or the unborn child

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TRC

Product number: H948363
Product name: (R)-5-HydroxymethylTolterodine
Packaging: 1mg
Price: $130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FH24399
Product name: (R)-5-Hydroxymethyl tolterodine
Packaging: 1g
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FH24399
Product name: (R)-5-Hydroxymethyl tolterodine
Packaging: 2g
Price: $160
Updated: 2021/12/16

ChemScene

Product number: CS-0825
Product name: Desfesoterodine
Purity: 99.58%
Packaging: 5mg
Price: $227
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FH24399
Product name: (R)-5-Hydroxymethyl tolterodine
Packaging: 5G
Price: $250
Updated: 2021/12/16

More

Less

(R)-5-HydroxyMethyl Tolterodine Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

(R)-5-HydroxyMethyl Tolterodine is a metabolite of Tolterodine (T535800), a muscarinic receptor antagonist used in the treatment of urinary incontinence.

Uses

A metabolite of Tolterodine, a muscarinic receptor antagonist used in the treatment of urinary incontinence.

Definition

ChEBI: Desfesoterodine is a diarylmethane.

in vivo

Desfesoterodine (PNU-200577; 5-Hydroxymethyl Tolterodine; 0.1 and 1 mg/kg; IV) significantly increases bladder compliance after moderate and high doses^[4].
In vivo, Desfesoterodine is significantly more potent at suppressing acetylcholine-induced urinary bladder contraction than electrically induced salivation in the anaesthetised cat (ID50=15 and 40 nmol/kg, respectively) ^[1].

Animal Model:	Female Sprague Dawley rats at ages 9 to 11 weeks weighing 180 to 250 g^[4]
Dosage:	0.1 and 1 mg/kg
Administration:	IV; single imidafenacin administration
Result:	Significantly increased bladder compliance after moderate and high doses.

(R)-5-HydroxyMethyl Tolterodine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(R)-5-HydroxyMethyl Tolterodine Suppliers

Canada 1 China 147 India 3 United Kingdom 1 United States 17 Global 169

Olix (Shanghai) Pharmaceutical Technology Co., Ltd

Tel: 17316404525 17316404525
Email: 209533805@qq.com
Country: China
ProdList: 9766
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

Shanghai SynFarm Pharmaceutical Technology Co., Ltd.

Tel: 021-50793966 18917198199
Fax: +86-21-50793967
Email: info@synfarm.com
Country: China
ProdList: 280
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

More

Less

View Lastest Price from (R)-5-HydroxyMethyl Tolterodine manufacturers

Career Henan Chemical Co

Product: 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol 207679-81-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2018-08-06

207679-81-0, (R)-5-HydroxyMethyl TolterodineRelated Search:

Fesoterodine Related Impurity 2 rac 5-Hydroxymethyl Tolterodine, 90% by HPLC Fesoterodine Impurity 6 SPM 907 (S)-(+)-O-Acetyl-L-mandelic acid Deoxy Fesoterodine 3-(3-Aminopropyl)benzoic Acid Hydrochloride Fesoterodine Diol Dimer Benzenepropanol, 2-hydroxy-5-(hydroxyMethyl)-γ-phenyl- FESOTERODINE Fesoterodine Impurity 5 (R)-5-HydroxyMethyl Tolterodine ForMate O-Isobutyryl (R)-Fesoterodine ICOFQCJKJOISKD-HSZRJFAPSA-N Fesoterodine Diol Dimer Monoester SOSXDUQUWXWKQR-OCQXTOTRSA-N Fesoterodine Related Impurity 4 Fesoterodinefumarate

(R)-5-Hydroxymethyl tolterodine

3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol

R-(+)-2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethylphenol

5-hydroxyMethyl tolterodine (PNU 200577)

Desfesoterodine

PNU 200577

PNU-200577

(R)-2-(3-(diisopropylaMino)-1-phenylpropyl)-4-(hydroxyMethyl)phenol (5-HMT)

Fesoterodine Diol

5-hydroxyMethyl Tolterodine (PNU 200577, 5-HMT, 5-HM)

Benzenemethanol, 3-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxy-

Fesoterodine fumarate Intermediate 2

Fesoterodine Impurity 1(Fesoterodine Diol)

2-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol

5-HM

5-HMT

Tolterodine 5-Hydroxymethyl (R)-Isomer

Fesoterodine Diol (R)-Isomer

(R)-5-HydroxyMethyl Tolterodine USP/EP/BP

Tolterodine 5-Hydroxymethyl Analog (R)-Isomer (Fesoterodine Diol (R)-Isomer)

Fesoterodine Diol (R)-Isomer (Tolterodine 5-Hydroxymethyl Analog (R)-Isomer)

2-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]-4-(hydroxymet...

5-Hydroxymethyl TolterodineQ: What is 5-Hydroxymethyl Tolterodine Q: What is the CAS Number of 5-Hydroxymethyl Tolterodine Q: What is the storage condition of 5-Hydroxymethyl Tolterodine Q: What are the applications of 5-Hydroxymethyl Tolterodine

Tolterodine Hydroxymethyl Analog

Desfesoterodine(5-Hydroxymethyl Tolterodine)

Non Sorodine Impurities

(R)-5-HydroxyMethyl Tolterodinel

5-HMT|||(R)-5-Hydroxymethyl Tolterodine|||PNU-200577|||5-HM|||5-hydroxymethyl Tolterodine

Desfesoterodine, 10 mM in DMSO

207679-81-0

07679-81-0

Chiral Reagents

Inhibitors

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals