2-PHENYL-ISONICOTINIC ACID
- Product Name
- 2-PHENYL-ISONICOTINIC ACID
- CAS No.
- 55240-51-2
- Chemical Name
- 2-PHENYL-ISONICOTINIC ACID
- Synonyms
- 2-Phenylisonicotinicaci;2-PHENYL-ISONICOTINIC ACID;2-Phenyl-4-pyridinecarboxylic acid;2-PHENYLPYRIDINE-4-CARBOXYLIC ACID;4-Pyridinecarboxylic acid, 2-phenyl-;2-Phenylpyridine-4-carboxylic acid, 4-Carboxy-2-phenylpyridine
- CBNumber
- CB1249787
- Molecular Formula
- C12H9NO2
- Formula Weight
- 199.21
- MOL File
- 55240-51-2.mol
2-PHENYL-ISONICOTINIC ACID Property
- Melting point:
- 270-271 °C
- Boiling point:
- 478.8±33.0 °C(Predicted)
- Density
- 1.241±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder to crystal
- pka
- 1.89±0.10(Predicted)
- color
- White to Orange to Green
- CAS DataBase Reference
- 55240-51-2
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CVT00064
- Product name
- 2-Phenylisonicotinic acid
- Packaging
- 1g
- Price
- $427
- Updated
- 2025/07/31
- Product number
- P2453
- Product name
- 2-Phenylpyridine-4-carboxylic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $189
- Updated
- 2025/07/31
- Product number
- P399390
- Product name
- 2-Phenylisonicotinic acid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 4H56-1-1B
- Product name
- 2-Phenylisonicotinic acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $132
- Updated
- 2021/12/16
- Product number
- V6577
- Product name
- 2-Phenylisonicotinic acid
- Packaging
- 1g
- Price
- $232
- Updated
- 2021/12/16
2-PHENYL-ISONICOTINIC ACID Chemical Properties,Usage,Production
Synthesis
66572-56-3
98-80-6
55240-51-2
Under nitrogen protection, 2-bromo-4-pyridinecarboxylic acid (0.210 g, 1.040 mmol) was dissolved in degassed 1,2-dimethoxyethane (DME, 8 mL). Tetrakis(triphenylphosphine)palladium(0) (0.060 g, 0.052 mmol) was added to the solution and the reaction mixture was stirred for 15 minutes. Subsequently, aqueous potassium carbonate (4.16 mL, 8.32 mmol) and phenylboronic acid (0.171 g, 1.403 mmol) were added. The reaction mixture was refluxed at 95 °C for 18 h, after which it was cooled to room temperature. The reaction mixture was filtered through diatomaceous earth and the pH was adjusted to 3-4 with acid to precipitate a white precipitate, which was filtered and washed with water. The white powdery product 2-phenyl-pyridine-4-carboxylic acid was obtained by recrystallization from 2-methoxyethanol. Yield: 0.106 g, 57% yield. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 7.44-7.60 (m, 3H), 7.71-7.86 (dd, J = 4.9, 1.5 Hz, 1H), 8.05-8.19 (m, 2H), 8.23-8.35 (t, J = 1.2 Hz, 1H), 8.79-8.93 (dd, J = 5.1, 0.8 Hz, 1H), 13.56-13.97 (s, 1H).UPLC-ESI analysis: retention time 1.37 min, m/z 200.5 [M + H]+ (purity 92%).
References
[1] Organic Letters, 2016, vol. 18, # 23, p. 6094 - 6097
[2] Patent: US2014/357650, 2014, A1. Location in patent: Paragraph 0456; 0457; 0458; 0459
[3] Journal of Medicinal Chemistry, 2014, vol. 57, # 7, p. 3053 - 3074
[4] Patent: WO2011/32269, 2011, A1. Location in patent: Page/Page column 34
[5] Patent: US2005/54627, 2005, A1. Location in patent: Page/Page column 44
2-PHENYL-ISONICOTINIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-PHENYL-ISONICOTINIC ACID manufacturers
- Product
- 2-Phenylisonicotinic Acid 55240-51-2
- Price
- US $3.00-9.00/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 50kg
- Release date
- 2025-07-28
- Product
- 2-Phenylisonicotinic Acid 55240-51-2
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-10
- Product
- 2-PHENYL-ISONICOTINIC ACID 55240-51-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95--99%
- Supply Ability
- 1ton
- Release date
- 2020-01-08