2-Bromo-3-nitro-5-(trifluoromethyl)pyridine

Product Name: 2-Bromo-3-nitro-5-(trifluoromethyl)pyridine
CAS No.: 1214336-90-9
Chemical Name: 2-Bromo-3-nitro-5-(trifluoromethyl)pyridine
Synonyms: 2-Bromo-3-nitro-5-(trifluoromethyl)pyridine;Pyridine, 2-bromo-3-nitro-5-(trifluoromethyl)-
CBNumber: CB12503634
Molecular Formula: C6H2BrF3N2O2
Formula Weight: 270.99
MOL File: 1214336-90-9.mol

More

Less

2-Bromo-3-nitro-5-(trifluoromethyl)pyridine Property

Boiling point:: 243℃
Density: 1.879
Flash point:: 101℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -5.67±0.20(Predicted)
Appearance: White to light yellow Solid

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: B679403
Product name: 2-Bromo-3-nitro-5-(trifluoromethyl)pyridine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 093294
Product name: 2-Bromo-3-nitro-5-(trifluoromethyl)pyridine
Purity: 95+%
Packaging: 250mg
Price: $473
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0363147
Product name: 2-BROMO-3-NITRO-5-(TRIFLUOROMETHYL)PYRIDINE
Purity: 95.00%
Packaging: 5MG
Price: $500.43
Updated: 2021/12/16

Matrix Scientific

Product number: 093294
Product name: 2-Bromo-3-nitro-5-(trifluoromethyl)pyridine
Purity: 95+%
Packaging: 1g
Price: $975
Updated: 2021/12/16

Ambeed

Product number: A112308
Product name: 2-Bromo-3-nitro-5-(trifluoromethyl)pyridine
Purity: 95%
Packaging: 100mg
Price: $43
Updated: 2021/12/16

More

Less

2-Bromo-3-nitro-5-(trifluoromethyl)pyridine Chemical Properties,Usage,Production

Synthesis

33252-64-1

1214336-90-9

General procedure for the synthesis of 2-bromo-3-nitro-5-(trifluoromethyl)pyridine from 2-hydroxy-3-nitro-5-(trifluoromethyl)pyridine: 3-nitro-5-(trifluoromethyl)pyridin-2-ol (3.12 g, 15 mmol) was dissolved in acetonitrile (25 ml) and slowly added to a solution of phosphorus tribromide (8.6 g, 30 mmol). The reaction mixture was stirred at room temperature for 12 hours and then heated to reflux for 4 hours. Upon completion of the reaction, the reaction solution was slowly poured into a rapidly stirred aqueous solution of sodium bicarbonate (11 g dissolved in 60 ml of water). The aqueous phase was extracted with dichloromethane (3 x 20 ml) and the organic phases were combined and washed sequentially with water (20 ml) and saturated sodium chloride solution (10 ml). The organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the target product 2-bromo-3-nitro-5-(trifluoromethyl)pyridine (2.44 g, 9.0 mmol).

References

[1] Patent: US2011/230483, 2011, A1. Location in patent: Page/Page column 32
[2] Patent: WO2013/38386, 2013, A1. Location in patent: Page/Page column 80; 81
[3] Patent: WO2013/38373, 2013, A1. Location in patent: Page/Page column 52
[4] Patent: WO2013/38378, 2013, A1. Location in patent: Page/Page column 48
[5] Patent: WO2013/38381, 2013, A1. Location in patent: Page/Page column 50

2-Bromo-3-nitro-5-(trifluoromethyl)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-Bromo-3-nitro-5-(trifluoromethyl)pyridine Suppliers

China 44 India 1 Ukraine 1 United States 6 Global 52

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 5000
Advantage: 55

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Cochemical Ltd.

Tel: 029-86115547 17791676824
Fax: 02151602123
Email: sales@cochemical.com
Country: China
ProdList: 3014
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 0512-0512-52358471 17715136450
Fax: 05125235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 12127
Advantage: 58

BioPharmaMatrix,Inc.

Tel: 0510-86010668
Fax: 0510-86010668
Email: sales@biopharmamatrix.com
Country: China
ProdList: 4739
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Anmike Chemical Co. Ltd.

Tel: 微信 17321281695 18019252918
Fax: 021-31261685
Email: sale@amkchem.com
Country: China
ProdList: 9405
Advantage: 55

Nanijing m&m biotechnology Co. ,Ltd.

Tel: 025-87782433 18021532344
Fax: 025-87782433
Email: 1345332203@qq.com
Country: China
ProdList: 4134
Advantage: 58

1214336-90-9, 2-Bromo-3-nitro-5-(trifluoromethyl)pyridineRelated Search:

2-BROMO-3-IODO-5-METHYLPYRIDINE 3-PYRIDINECARBOXYLIC ACID, 6-BROMO-5-CHLORO- 2-BroMo-3-chloroisonicotinaldehyde 2-Bromo-3-fluoro-4-formylpyridine 2-bromo-3-chloroisonicotinic acid 2-Bromo-3-iodo-5-(trifluoromethyl)pyridine 2-Bromo-3-chlorobenzonitrile 2-broMo-3-Methyl-pyridine-3-carboxyl acid 2-Bromo-3-fluoropyridin-4-ol 2-BROMO-3-FLUORO-4-METHYLPYRIDINE 2-BROMO-6-CHLORO-3-NITROPYRIDINE 2-Bromo-3-fluoro-4-pyridinecarboxylic acid 2-Bromo-3-chloro-6-(trifluoromethyl)pyridine 2-BROMO-NICOTINONITRILE 2-BROMO-3-CHLOROPYRIDINE-4-BORONIC ACID Methyl 2-BroMo-3-fluoroisonicotinate 2-bromo-3-methoxypyrazine 2-Bromo-3-chloro-4-methylpyridine

2-Bromo-3-nitro-5-(trifluoromethyl)pyridine

Pyridine, 2-bromo-3-nitro-5-(trifluoromethyl)-

1214336-90-9

C6H2BrF3N2O2