2-BROMO-6-CHLORO-3-NITROPYRIDINE

Product Name: 2-BROMO-6-CHLORO-3-NITROPYRIDINE
CAS No.: 91678-23-8
Chemical Name: 2-BROMO-6-CHLORO-3-NITROPYRIDINE
Synonyms: 2-Amino-2-Methyl pyridine;2-BROMO-6-CHLORO-3-NITROPYRIDINE;Pyridine,2-broMo-6-chloro-3-nitro-;2-BROMO-6-CHLORO-3-NITROPYRIDINE ISO 9001：2015 REACH
CBNumber: CB0537836
Molecular Formula: C5H2BrClN2O2
Formula Weight: 237.44
MOL File: 91678-23-8.mol

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2-BROMO-6-CHLORO-3-NITROPYRIDINE Property

Boiling point:: 277.2±35.0℃ (760 Torr)
Density: 1.936±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:: 121.5±25.9℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: -7.39±0.10(Predicted)
Appearance: Light yellow to yellow Solid
InChI: InChI=1S/C5H2BrClN2O2/c6-5-3(9(10)11)1-2-4(7)8-5/h1-2H
InChIKey: WISCKHBEOBONJA-UHFFFAOYSA-N
SMILES: C1(Br)=NC(Cl)=CC=C1[N+]([O-])=O

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B684583
Product name: 2-Bromo-6-chloro-3-nitropyridine
Packaging: 25mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B684583
Product name: 2-Bromo-6-chloro-3-nitropyridine
Packaging: 50mg
Price: $55
Updated: 2021/12/16

ChemScene

Product number: CS-W008871
Product name: 2-Bromo-6-chloro-3-nitropyridine
Purity: ≥97.0%
Packaging: 250mg
Price: $39
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB58219
Product name: 2-Bromo-6-chloro-3-nitropyridine
Packaging: 100mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-W008871
Product name: 2-Bromo-6-chloro-3-nitropyridine
Purity: ≥97.0%
Packaging: 1g
Price: $70
Updated: 2021/12/16

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2-BROMO-6-CHLORO-3-NITROPYRIDINE Chemical Properties,Usage,Production

Synthesis

27048-04-0

91678-23-8

Example P3: Preparation of 2-bromo-6-chloro-3-nitropyridine. Under nitrogen protection, tert-butyl nitrite (990 mg, 9.60 mmol) was added batchwise to a stirred solution of 2-amino-6-chloro-3-nitropyridine (1.00 g, 5.76 mmol) and copper(II) bromide (1.56 g, 6.91 mmol) in acetonitrile (25 mL) at a reaction temperature of 65 °C. Stirring of the reaction mixture was continued for 30 minutes. After completion of the reaction, it was cooled to room temperature and the reaction mixture was partitioned between ethyl acetate and 2M aqueous hydrochloric acid solution. The organic layer was separated and dried with anhydrous magnesium sulfate and subsequently concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: heptane-dichloromethane gradient) to afford the target product 2-bromo-3-nitro-6-chloropyridine (1.11 g, 81% yield) as a yellow solid. Mass spectrometry (EI) analysis showed m/z of 235.9/237.9 (relative abundance 78/100, [M]+).

References

[1] Patent: US2007/185154, 2007, A1. Location in patent: Page/Page column 10
[2] Patent: US2015/57260, 2015, A1. Location in patent: Paragraph 0575; 0576
[3] Patent: WO2015/25026, 2015, A1. Location in patent: Page/Page column 142
[4] Journal of Medicinal Chemistry, 2017, vol. 60, # 24, p. 10151 - 10171

2-BROMO-6-CHLORO-3-NITROPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BROMO-6-CHLORO-3-NITROPYRIDINE Suppliers

China 91 Germany 1 India 2 United Kingdom 1 United States 7 Global 102

wuhan Dekray Biomedical Technology Co.,Ltd

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Pure Chemistry Scientific Inc.

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Wuhan ariel chemical Co., LTD.

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Chiba Pharmaceutical Science and technology Co, Ltd.

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NovoChemy Ltd.

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View Lastest Price from 2-BROMO-6-CHLORO-3-NITROPYRIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Bromo-6-chloro-3-nitropyridine 91678-23-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2019-12-27

Dideu Industries Group Limited

Product: 2-BROMO-6-CHLORO-3-NITROPYRIDINE 91678-23-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-03

Career Henan Chemical Co

Product: 2-BROMO-6-CHLORO-3-NITROPYRIDINE 91678-23-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-08

91678-23-8, 2-BROMO-6-CHLORO-3-NITROPYRIDINERelated Search:

2-Bromo-3-iodo-5-(trifluoromethyl)pyridine 2-Bromo-3-chlorobenzonitrile 2-broMo-3-Methyl-pyridine-3-carboxyl acid 2-Bromo-3-fluoropyridin-4-ol 2-Bromo-3-nitro-5-(trifluoromethyl)pyridine 2-BROMO-3-FLUORO-4-METHYLPYRIDINE 5-BROMO-2-CHLORO-3-NITROPYRIDINE,5-BROMO-2-CHLORO-3-NITROPYRIDINE 98% 2-BROMO-3-CHLORO-5-NITROPYRIDINE 2-Amino-5-bromo-4-chloro-3-nitropyridine 3-Bromo-2-chloro-5-nitropyridine 98%,3-BROMO-2-CHLORO-5-NITROPYRIDINE 2-bromo-5-chloro-2-nitropyridine 3-BROMO-4-CHLORO-5-NITROPYRIDINE 2-BROMO-5-CHLORO-3-NITROPYRIDINE 2-BROMO-6-CHLOROPYRIDINE 2-BROMO-6-CHLORO-3-NITROPYRIDINE 2-BROMO-PYRIDIN-3-YLAMINE HCL 2-Bromo-3-nitropyridine 4-BROMO-3-CHLORO-5-NITROPYRIDINE

2-BROMO-6-CHLORO-3-NITROPYRIDINE

Pyridine,2-broMo-6-chloro-3-nitro-

2-BROMO-6-CHLORO-3-NITROPYRIDINE ISO 9001：2015 REACH

2-Amino-2-Methyl pyridine

91678-23-8

Heterocycle-Pyridine series