ChemicalBook > CAS DataBase List > SACLOFEN

SACLOFEN

Product Name
SACLOFEN
CAS No.
125464-42-8
Chemical Name
SACLOFEN
Synonyms
SACLOFEN;Saclofen, 10 mM in DMSO;Saclofen, GABAB antagonist;SACLOFEN ISO 9001：2015 REACH;SACLOFEN SELECTIVE GABA(B) REC;3-Amino-2-(4-chlorophenyl)propane-1-sulfonicaci;3-AMINO-2-(4-CHLOROPHENYL)-PROPANE SULFONIC ACID;3-AMino-2-(4-chlorophenyl)propane-1-sulfonic acid;β-(aminomethyl)-4-chlorobenzeneethanesulfonic acid;(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID
CBNumber
CB1250606
Molecular Formula
C9H12ClNO3S
Formula Weight
249.71
MOL File
125464-42-8.mol
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SACLOFEN Property

Melting point:
310-315℃ (decomposition)
Density 
1.437±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
0.1 M NaOH: 20 mg/mL
form 
solid
pka
1.15±0.50(Predicted)
color 
white
Water Solubility 
Soluble in water (10mM)
InChIKey
JYLNVJYYQQXNEK-UHFFFAOYSA-N
CAS DataBase Reference
125464-42-8(CAS DataBase Reference)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S166
Product name
Saclofen
Purity
solid
Packaging
5mg
Price
$326
Updated
2025/07/31
Cayman Chemical
Product number
17355
Product name
Saclofen
Purity
≥98%
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
17355
Product name
Saclofen
Purity
≥98%
Packaging
10mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
17355
Product name
Saclofen
Purity
≥98%
Packaging
50mg
Price
$671
Updated
2024/03/01
Tocris
Product number
0246
Product name
Saclofen
Purity
≥99%(HPLC)
Packaging
10
Price
$216
Updated
2021/12/16
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SACLOFEN Chemical Properties,Usage,Production

Uses

Saclofen is a GABABR antagonist that has been shown to reduced leukocyte migration and increase Fos expression in T7-T11 sympathetic preganglionic neurons

Uses

Saclofen has been used as a GABAB receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats.

Definition

ChEBI: 3-amino-2-(4-chlorophenyl)-1-propanesulfonic acid is an organochlorine compound.

Biological Activity

Selective antagonist at GABA B receptors.

Biochem/physiol Actions

Saclofen might possess sympathetic nervous system-dependent anti-inflammatory action.

storage

Room temperature

SACLOFEN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from SACLOFEN manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
SACLOFEN 125464-42-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Shaanxi Dideu Medichem Co. Ltd
Product
Saclofen 125464-42-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%+
Supply Ability
100 tons
Release date
2019-12-30
Career Henan Chemical Co
Product
SACLOFEN 125464-42-8
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-02-01

125464-42-8, SACLOFENRelated Search:

(R)-Saclofen SACLOFEN HYDROCHLORIDE SACLOFEN((RS)-3-AMINO-2-(4-CHLOROPHENY SACLOFEN 2-HYDROXYSACLOFEN

  • SACLOFEN
  • (RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID
  • SACLOFEN SELECTIVE GABA(B) REC
  • BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID
  • BETA-(AMINOMETHYL)-4-CHLORO-BENZENEETHANESULPHONIC ACID
  • 3-AMINO-2-(4-CHLOROPHENYL)-PROPANE SULFONIC ACID
  • β-(aminomethyl)-4-chlorobenzeneethanesulfonic acid
  • 3-AMino-2-(4-chlorophenyl)propane-1-sulfonic acid
  • Benzeneethanesulfonic acid, β-(aminomethyl)-4-chloro-
  • 3-Amino-2-(4-chlorophenyl)propane-1-sulfonicaci
  • SACLOFEN ISO 9001：2015 REACH
  • Saclofen, GABAB antagonist
  • Saclofen, 10 mM in DMSO
  • 125464-42-8
  • C9H12NO3SCl
  • C9H12CINO3S
  • GABA/Glycine receptor
  • GABA