1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone
- Product Name
- 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone
- CAS No.
- 1125812-58-9
- Chemical Name
- 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone
- Synonyms
- 1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one;afoxolaner-002;afoxolaner Impurity 6;1-[3-Chloro-5-trifluoromethylphenyl;2,2,2-trifluoro-3'-chloro-5'-trifluoromethylacetophenone;3'-Chloro-5'-trifluoroMethyl-2,2,2-trifluoroacetophenone;3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone;3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone;1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone;Ethanone, 1-[3-chloro-5-(trifluoromethyl)phenyl]-2,2,2-trifluoro-
- CBNumber
- CB12514588
- Molecular Formula
- C9H3ClF6O
- Formula Weight
- 276.56
- MOL File
- 1125812-58-9.mol
1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Property
- Boiling point:
- 203℃
- Density
- 1.512
- Flash point:
- 77℃
- storage temp.
- 2-8°C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- AS146793
- Product name
- 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone
- Purity
- 95%
- Packaging
- 1g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- HCH0361882
- Product name
- 1-(3-CHLORO-5-(TRIFLUOROMETHYL)PHENYL)-2,2,2-TRIFLUOROETHANONE
- Purity
- 95.00%
- Packaging
- 0.25G
- Price
- $243
- Updated
- 2021/12/16
- Product number
- A744788
- Product name
- 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $21
- Updated
- 2021/12/16
- Product number
- A744788
- Product name
- 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $28
- Updated
- 2021/12/16
- Product number
- A744788
- Product name
- 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone
- Purity
- 95+%
- Packaging
- 1g
- Price
- $79
- Updated
- 2021/12/16
1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Chemical Properties,Usage,Production
Uses
1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
Cool the solution containing compound III (74.4g, 0.255mol containing compound III) to -100, and add 120g of sulfuric acid with a mass fraction of 92.5% to the above system while keeping the temperature below 0. After acidification, continue to react and keep for 1.5h, and then add 126.7g of 33% sodium nitrite aqueous solution (containing diazotizing reagent sodium nitrite 0.612mol) into the system uniformly within 2h, and keep the temperature at 0 The following reaction is carried out for 2 hours, and the system is heated to room temperature after full reaction, 111.1 g of 50% hypophosphorous acid and 0.67 g of cuprous oxide are added, and the reaction is stirred for 2 hours while keeping temperature. After the reaction is over, stand to separate the layers, and wash the organic layer with a 5% sodium bicarbonate aqueous solution, dry with anhydrous magnesium sulfate, and rectify to obtain a clear and transparent oily liquid 1-[3-chloro-5-(trifluoromethyl) (Yl)phenyl]-2,2,2-trifluoroethanone 66.9, content 99.5%, yield 87.2%.
1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Preparation Products And Raw materials
Raw materials
Preparation Products
1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Suppliers
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View Lastest Price from 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone manufacturers
- Product
- 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone 1125812-58-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.10000000149011612kg
- Purity
- 98.0% min
- Supply Ability
- 1ton/month
- Release date
- 2023-06-09
- Product
- 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone 1125812-58-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-14