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FostaMatinib DisodiuM Hexahydrate

Product Name
FostaMatinib DisodiuM Hexahydrate
CAS No.
914295-16-2
Chemical Name
FostaMatinib DisodiuM Hexahydrate
Synonyms
Fostamatinib Na;R788 (disodiuM hexahydrate);FostaMatinib DisodiuM Hexahydrate;Fostamatinib disodium salt hexahydrate;R788 Disodium Hexahydrate (Fostamatinib Disodium Hexahydrate);Fostamatinib Disodium Hexahydrate DISCONTINUED. Please see R070115.;6-[[5-Fluoro-2-[(3,4,5-triMethoxyphenyl)aMino]-4-pyriMidinyl]aMino]-2,2-diMethyl-4-[(phosphonooxy)Methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one SodiuM Salt Hydrate;Sodium (6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl)methyl phosphate hexahydrate;6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one disodium salt hexahydrate;2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-, disodium salt, hexahydrate
CBNumber
CB12545135
Molecular Formula
C23H24FN6Na2O9P
Formula Weight
624.4231642
MOL File
914295-16-2.mol
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FostaMatinib DisodiuM Hexahydrate Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to gray
InChIKey
HSYBQXDGYCYSGA-UHFFFAOYSA-L
SMILES
C1(C)(C)Oc2ccc(Nc3c(F)cnc(Nc4cc(OC)c(OC)c(OC)c4)n3)nc2N(COP([O-])([O-])=O)C1=O.[Na+].[Na+]
CAS DataBase Reference
914295-16-2
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-2688
Product name
Fostamatinib(disodiumhexahydrate)
Purity
99.92%
Packaging
5mg
Price
$96
Updated
2021/12/16
ChemScene
Product number
CS-2688
Product name
Fostamatinib(disodiumhexahydrate)
Purity
99.92%
Packaging
10mg
Price
$144
Updated
2021/12/16
Biosynth Carbosynth
Product number
FF23602
Product name
Fostamatinib disodium hexahydrate
Packaging
10mg
Price
$225
Updated
2021/12/16
ChemScene
Product number
CS-2688
Product name
Fostamatinib(disodiumhexahydrate)
Purity
99.92%
Packaging
50mg
Price
$432
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0013911
Product name
FOSTAMATINIB DISODIUM HEXAHYDRATE
Purity
95.00%
Packaging
5MG
Price
$463.1
Updated
2021/12/16
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FostaMatinib DisodiuM Hexahydrate Chemical Properties,Usage,Production

Uses

A spleen tyrosine kinase inhibitor prodrug for the treatment of inflammatory diseases. An anti-inflammatory agent.

Uses

A spleen tyrosine kinase inhibitor prodrug for the treatment of inflammatory diseases.

in vivo

Fostamatinib (R788) is highly bioavailable, and rapidly absorbed in Louvain rats. R406 following a single oral dose of R788 10 mg/kg or 20 mg/kg: AUC0-16 hrs= 10618 ng*h/mL and 30650 ng*h/mL respectively; Cmax=2600 ng/mL and 6500 ng/mL respectively (observed at 1 hour); t1/2=4.2 hours. The prodrug was not detected in plasma suggesting R788 is completely converted to R406[1].

FostaMatinib DisodiuM Hexahydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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FostaMatinib DisodiuM Hexahydrate Suppliers

Canada 1 China 91 India 2 United Kingdom 1 United States 7 Global 102
Suzhou Zehou Biotechnology Co. , Ltd.
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0512-68716880 19984816880
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18075373931
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sales@growingchem.com
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China
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CAREBIO PHARMA
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jackyfan@rebornpharma.com
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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Chembest Research Laboratories Limited
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+86-21-20908456
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021-58180499
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sales@BioChemBest.com
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Jia Xing Isenchem Co.,Ltd
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0573-85285100
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isenchem@163.com
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Chemsky (shanghai) International Co.,Ltd
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021-50135380
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shchemsky@sina.com
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Haoyuan Chemexpress Co., Ltd.
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021-58950125
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(86) 21-58955996
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info@chemexpress.com
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China
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EnliPharma Technology Co., Ltd
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0551-66399836 18955197623
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sales@enlipharma.com
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China
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ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185
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sales-cpd@caerulumpharma.com
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China
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Watson Biotechnology Co.,Ltd
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027-59207879 1972026995 18140587686
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QQ：1972026995
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sales@3600chem.com
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China
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View Lastest Price from FostaMatinib DisodiuM Hexahydrate manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.
Product
Fostamatinib Disodium Hexahydrate 914295-16-2
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99% HPLC
Supply Ability
10000
Release date
2024-09-20
Hebei Yanxi Chemical Co., Ltd.
Product
FostaMatinib DisodiuM Hexahydrate 914295-16-2
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
Fostamatinib Disodium Hexahydrate 914295-16-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

914295-16-2, FostaMatinib DisodiuM HexahydrateRelated Search:

Fosaprepitant dimeglumine Combretastatin A4 phosphate disodium salt Sunitinib LOXO-101 Dasatinib Fostamatinib

  • FostaMatinib DisodiuM Hexahydrate
  • 6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one disodium salt hexahydrate
  • Fostamatinib disodium salt hexahydrate
  • 6-[[5-Fluoro-2-[(3,4,5-triMethoxyphenyl)aMino]-4-pyriMidinyl]aMino]-2,2-diMethyl-4-[(phosphonooxy)Methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one SodiuM Salt Hydrate
  • R788 (disodiuM hexahydrate)
  • Fostamatinib Na
  • 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-, disodium salt, hexahydrate
  • R788 Disodium Hexahydrate (Fostamatinib Disodium Hexahydrate)
  • Fostamatinib Disodium Hexahydrate DISCONTINUED. Please see R070115.
  • Sodium (6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl)methyl phosphate hexahydrate
  • 914295-16-2
  • C23H26FN6O9P6H2O2Na
  • C23H36FN6Na2O15P
  • Phosphorylating and Phosphitylating Agents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals