Sodium salicylate

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Sodium salicylate

Product Name: Sodium salicylate
CAS No.: 54-21-7
Chemical Name: Sodium salicylate
Synonyms: SALICYLATE;NASAL;alysine;2-Hydroxybenzoate;clin;ardall;aroall;kerosal;nadisal;salisod
CBNumber: CB1255762
Molecular Formula: C7H5NaO3
Formula Weight: 160.1
MOL File: 54-21-7.mol

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Sodium salicylate Property

Melting point:: >300 °C (lit.)
Density: 0.32 g/cm3 (20℃)
storage temp.: Store at +15°C to +25°C.
solubility: 1000g/l
form: Crystals or Crystalline Powder
color: White
PH: 6.5 (100g/l, H2O, 20℃)
Odor: wh. lustrous cryst. scales or amorphous powd., odorless or faint odor, saline taste
Water Solubility: 1000 g/L (20 ºC)
Sensitive: Light Sensitive
Merck: 14,8332
BRN: 3732792
Stability:: Stable. Incompatible with mineral acids, metallic salts, iodine. May be light-sensitive.
InChIKey: ABBQHOQBGMUPJH-UHFFFAOYSA-M
LogP: 2.061 (est)
CAS DataBase Reference: 54-21-7(CAS DataBase Reference)
EPA Substance Registry System: Sodium salicylate (54-21-7)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-41-36/37/38-36
Safety Statements: 26-36
WGK Germany: 1
RTECS: VO5075000
F: 8
Autoignition Temperature: >250 °C
TSCA: Yes
HS Code: 29182100
Toxicity: LD50 i.p. in rats: 780 mg/kg (Goldenthal)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3238
Product name: Sodium Salicylate
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 1G
Price: $173
Updated: 2024/03/01

Sigma-Aldrich

Product number: 567630
Product name: Sodium Salicylate - CAS 54-21-7 - Calbiochem
Purity: A cell-permeable, non-steroidal anti-inflammatory agent that interferes with TNF-induced NF-κB activation by inhibiting phosphorylation and subsequent degradation of the IκB-α protein.
Packaging: 5G
Price: $56.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: 31493
Product name: Sodium salicylate
Purity: puriss. p.a., Reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)
Packaging: 1kg
Price: $208
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1.06601
Product name: Sodium salicylate
Purity: for analysis EMSURE?
Packaging: 250g
Price: $79.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1614636
Product name: Sodium salicylate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 500mg
Price: $420
Updated: 2024/03/01

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Sodium salicylate Chemical Properties,Usage,Production

Description

Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure. Historically, it has been synthesized from methyl salicylate (found in wintergreen plants or the bark of sweet birch tree) by reacting it with an excess of sodium hydroxide and heating it under reflux.

Chemical Properties

Sodium salicylate is of the salicylate family and this compound is known to trigger Reye's Syndrome in children and adults, usually following a viral infection such as influenza or chicken pox. Products containing such salicylates should not be given to children under the age of 19.

Chemical Properties

Sodium salicylate, HOC6H4COONa, is a shiny, white powder with sweetish taste and mild aromatic aroma that is soluble in water,glycerol, and alcohol.Used in medicine and as a preservative.

Uses

It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non - steroidal anti - inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. It is also a potential replacement for aspirin for people sensitive to it. It may also be used as a phosphor for the detection of vacuum ultra violet radiation and electrons.

Uses

keratolytic

Uses

In manufacture of aspirin, methyl salicylate, and other salicylates. Coupling agent for azo dyes. Has been used as food preservative.

Definition

A salt or ester of salicylic acid.

brand name

Alysine (Marion Merrell Dow).

General Description

Sodium salicylate may be prepared by the reaction, in aqueoussolution, by adding equal molar ratio of salicylic acidand sodium bicarbonate; evaporating to dryness yields thewhite salt. In solution, particularly in the presence of sodiumbicarbonate, the salt will darken on standing. This is the saltof choice for salicylate medication and usually is administeredwith sodium bicarbonate to lessen gastric distress, or itis administered in enteric coated tablets. However, the useof sodium bicarbonate is ill advised, because it decreases theplasma levels of salicylate and increases the excretion offree salicylate in the urine.
Sodium salicylate, even though not as potent as aspirinfor pain relief, also has less GI irritation and is useful for patientswho are hypersensitive to aspirin.

Biochem/physiol Actions

Cell permeable: yes

Safety Profile

Experimental poison by subcutaneous route. Moderately toxic to humans by ingestion. Moderately toxic experimentally by ingestion, intraperitoneal, and intravenous routes. An experimental teratogen. Human systemic effects by multiple and unspecified routes: toxic psychosis, excitement, respiratory stimulation, nausea or vomiting, and sweating. Experimental reproductive effects. Mutation data reported. A powerful irritant which affects the central nervous system. Incompatible with ferric salts, mineral acids, iodme, lead acetate, silver nitrate, sodium phosphate powder. When heated to decomposition it emits toxic fumes of Na2O.

Sodium salicylate Preparation Products And Raw materials

Raw materials

Sodium dithionite Salicylic acid Ethylenediaminetetraacetic acid

Preparation Products

3,6-DICHLORO-2-HYDROXY BENZOIC ACID Salicylic acid Benzyl salicylate Mordant Yellow 1

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View Lastest Price from Sodium salicylate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Sodium salicylate 54-21-7
Price: US $0.00/KG
Min. Order: 25KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-09

Hebei Weibang Biotechnology Co., Ltd

Product: Sodium salicylate 54-21-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-21

Henan Suikang Pharmaceutical Co.,Ltd.

Product: Sodium salicylate 54-21-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.0%
Supply Ability: 1tons
Release date: 2024-04-26

54-21-7, Sodium salicylateRelated Search:

Sodium hydroxide Sodium 4-hydroxybenzoate Sodium benzoate Sodium bicarbonate Diclofenac sodium Methyl salicylate Salicylic acid P-AMINOSALICYLIC ACID SODIUM SALT Sodium citrate Trisodium phosphate Sodium acetate SALICYLIC ACID N-PROPYL ESTER 2-Cyanophenol 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Salicylaldoxime Benzyl salicylate AMMONIUM SALICYLATE 2-Hydroxyethyl salicylate Sodium Salicylate Solution

Sdium salicylate

Sodium Salicylate 2-Hydroxybenzoic acid monosodium salt Sodium o-hydroxybenzoate

Sodium salicylate BP98

SODIUM SALICYLATE R. G., REAG. PH. EUR.

SODIUM SALICYLATE, REAGENTPLUS TM, >= 99.5%

SODIUM SALICYLATE, PH EUR

SODIUM SALICYLATE, REAGENTPLUS, >=99%

SodiumSalicylatePurified

SodiumSalicylateGr

Sodiumsalicylate,99%

NASAL

NATRII SALICYLAS

SALICYCLIC ACID, SODIUM SALT

SALICYLIC ACID SODIUM SALT

SALICYLIC ACID, NA

SODIUM 2-HYDROXYBENZOATE

SODIUM SALICYLATE

Benzoicacid,2-hydroxy-,monosodiumsalt

2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt

2-Hydroxybenzoic acid sodium salt, Natrii salicylas, Salicylic acid sodium salt

Camporisin

Glutosalyl

Idocyll novum

2-Hydroxybenzoate

2-Hydroxybenzoic acid anion

Salicylic acid anion

SODIUMSALICYLATE,CRYSTAL,REAGENT

SODIUMSALICYLATE,CRYSTAL,USP

SALICYLATE

Sodium Salicylate, Crystal

Sodium salicylate,2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt

Sodium Salicylate (500 mg)

Salicylic acid, sodium salt, 99+%

SODIUM SALICYLATE REAGENT

Salicylic acid, sodiuM salt, 99+% 1KG

Salicylic acid, sodiuM salt, 99+% 250GR

SODIUM SALICYLATE FOR ANALYSIS EMSURE

alysine

ardall

aroall

Sodium salicylate, 100ppm

Sodium salicylate puriss. p.a., Reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)

Sodium salicylate Vetec(TM) reagent grade, 99%

SODIUM SALICYLATE CRYSTALLIZED

SODIUM SALICYLATE, REAGENTPLUS TM, >

salicylic acid sodium

sodium salicylate usp

Sodium Salicylate/Salicylic acid sodium salt

Sodium sallicylate

SODIUM SALICYLATE TECHNICAL GRADE

clin

diuretin

enterosalicyl

enterosalil

idocylnovum

kerasalicyl

kerosal

magsalyl