Dabigatran Acyl-β-D-Glucuronide

Product Name: Dabigatran Acyl-β-D-Glucuronide
CAS No.: 1015167-40-4
Chemical Name: Dabigatran Acyl-β-D-Glucuronide
Synonyms: Dabigatran Impurity 110;Dabigatran Acyl Glucuronide;Dabigatran Acyl-β-D-Glucuronide;Dabigatran Acyl-β-D-Glucuronide;Dabigatran β-Acyl Glucuronide D4;Dabigatran Acyl-Beta-D-Glucuronide;Dabigatran Acyl-?-D-Glucuronide TFA Salt;Dabigatran Acyl-?-D-Glucuronide-D3 TFA Salt;Dabigatran Acyl--D- glucuronide trifluroacetic acid;Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt
CBNumber: CB12558083
Molecular Formula: C31H33N7O9
Formula Weight: 647.63522
MOL File: 1015167-40-4.mol

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Dabigatran Acyl-β-D-Glucuronide Property

Melting point:: >155°C (dec.)
Boiling point:: 968.1±75.0 °C(Predicted)
Density: 1.57±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Heated), Water
form: Solid
pka: 2.68±0.70(Predicted)
color: Off-White to Light Brown
Stability:: Hygroscopic, Unstable in Solution

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26655
Product name: Dabigatran Acyl-β-D-Glucuronide
Packaging: 1mg
Price: $893
Updated: 2023/06/20

TRC

Product number: D100085
Product name: DabigatranAcyl-β-D-GlucuronideTrifluoroaceticAcidSalt(80%)
Packaging: 1mg
Price: $485
Updated: 2021/12/16

TRC

Product number: D100085
Product name: DabigatranAcyl-β-D-GlucuronideTrifluoroaceticAcidSalt(80%)
Packaging: 10mg
Price: $3875
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 79818
Product name: Dabigatranacyl-β-D-glucuronide
Packaging: 5mg
Price: $2390
Updated: 2021/12/16

Chemtos

Product number: D-2143
Product name: Dabigatran-acyl-glucuronide(isomermix)
Packaging: 10mg
Price: $2990
Updated: 2021/12/16

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Dabigatran Acyl-β-D-Glucuronide Chemical Properties,Usage,Production

Description

Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran . The prodrug of dabigatran, dabigatran etexilate , is hydrolyzed by plasma esterases to form dabigatran, which is metabolized primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT2B15 to form dabigatran acyl-β-D-glucuronide. Dabigatran acyl-β-D-glucuronide increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma equipotently to dabigatran.

Uses

The major metabolite of Dabigatran (D100090) in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys. ?NMR analysis confirmed the structures of the four metabolites as the 1-O-acylglucuronide (β anomer) and the 2-O-, 3-O-, and 4-O-acylglucuronides (α and β anomers).

Uses

A metabolite of Dabigatran.

Uses

Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt is a major metabolite of Dabigatran (D100090) in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys. NMR analysis confirmed the structures of the four metabolites as the 1-O-acylglucuronide (β anomer) and the 2-O-, 3-O-, and 4-O-acylglucuronides (α and β anomers).

Dabigatran Acyl-β-D-Glucuronide Preparation Products And Raw materials

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1015167-40-4, Dabigatran Acyl-β-D-GlucuronideRelated Search:

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Dabigatran Acyl--D-glucuronide D3 trifluoroacetate saltQ: What is Dabigatran Acyl--D-glucuronide D3 trifluoroacetate salt Q: What is the CAS Number of Dabigatran Acyl--D-glucuronide D3 trifluoroacetate salt Q: What is the storage condition of Dabigatran Acyl--D-glucuronide D3 trifluoroacetate salt Q: What are the applications of Dabigatran Acyl--D-glucuronide D3 trifluoroacetate salt

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Dabigatran Acyl-β-D-Glucuronide

β-Alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-, β-D-glucopyranuronosyl ester

Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt

Dabigatran Impurity 110

1015167-40-4

C31H33N7O9

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