ChemicalBook > CAS DataBase List > Ascorbyl glucoside

Ascorbyl glucoside

Product Name
Ascorbyl glucoside
CAS No.
129499-78-1
Chemical Name
Ascorbyl glucoside
Synonyms
Ascorbic acid 2-glucoside;AA-2G;Vitamin C Glucoside;Ascorbate glucoside;2-O-α-D-Glucopyranosyl-L-ascorbic Acid;VCG;LGB-AA2G;Ascofresh;2-O-αASCORBYL GLUCOSIDE
CBNumber
CB6959339
Molecular Formula
C12H18O11
Formula Weight
338.26
MOL File
129499-78-1.mol
More
Less

Ascorbyl glucoside Property

Melting point:
158-163℃
Boiling point:
785.6±60.0 °C(Predicted)
Density 
1.83±0.1 g/cm3(Predicted)
vapor pressure 
0Pa at 25℃
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
3.38±0.10(Predicted)
form 
Powder
color 
White to Off-white
Water Solubility 
Soluble in water. (879 g/L) at 25°C.
λmax
260nm(H2O)(lit.)
InChIKey
MLSJBGYKDYSOAE-DCWMUDTNSA-N
LogP
-2 at 20℃
Surface tension
71mN/m at 1g/L and 20℃
More
Less

Safety

WGK Germany 
3
HS Code 
2938909090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00390
Product name
Ascorbyl Glucoside
Purity
≥98% (HPLC)
Packaging
1g
Price
$158
Updated
2025/07/31
Sigma-Aldrich
Product number
PHR1433
Product name
Ascorbyl Glucoside
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
1g
Price
$117.8
Updated
2025/07/31
TCI Chemical
Product number
G0394
Product name
2-O-α-D-Glucopyranosyl-L-ascorbic Acid
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$31
Updated
2025/07/31
TCI Chemical
Product number
G0394
Product name
2-O-α-D-Glucopyranosyl-L-ascorbic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$91
Updated
2025/07/31
TRC
Product number
G596633
Product name
2-O-a-D-Glucopyranosyl-L-ascorbicAcid
Packaging
10mg
Price
$45
Updated
2021/12/16
More
Less

Ascorbyl glucoside Chemical Properties,Usage,Production

Description

Ascorbyl glucoside is a natural active substance containing Vitamin C structure, but it is stable. Ascorbyl glucoside can effectively inhibit formation of melanin, dilute the skin color, reduce age spots and freckles pigmentation.
Ascorbic Acid 2-Glucoside(AA-2G) was originally developed as a quasi-drug cosmetic product in Japan to lighten the overall tone of the skin and reduce the pigmentation in age spots and freckles. Further research has shown other dramatic benefits and today AA-2G is used all over the world-not only for whitening but also for brightening dull looking skin, reversing the effects of aging, and in sunscreen products for protection.

Uses

According to the manufacturer, ascorbyl glucoside functions as a time-release version of vitamin C (ascorbic acid), and therefore is more stable than traditional ascorbic acid. It is considered to have skin-lightening and anti-hyperpigmentation properties, thanks to an ability to suppress melanin production. Its skinbrightening capacities are attributed to an apparent ability to reduce pre-existing melanin levels (as in the case of freckles or age spots). Ascorbyl glucoside could also help promote collagen synthesis and help reduce skin inflammation. It is found in antiaging, anti-wrinkle, and sun care products.

Uses

2-O-alpha-D-Glucopyranosyl-L-ascorbic acid reduce the free radicals that result from UV irradiation of the skin, and significantly reduce cell damage and photo-aging. It also promotes collagen synthesis. It can function as an antioxidant.

Definition

ChEBI: L-Ascorbic acid-2-glucoside is a glycoside.

benefits

Ascorbyl glucoside (AG) is a whitening agent widely used in cosmetic formulations. Studies have shown that AG has a depigmenting effect on UVB pigmentation as a tyrosinase inhibitor or after being converted into free ascorbic acid by intrinsic epidermal glucosidase[1]. It has the following benefits for the skin:
 (1) Whitening effect: brightens skin tone, lightens pigmentation and improves solar vitiligo.
 (2) Antioxidant effect: neutralizes free radicals and prevents skin damage.
 (3) High safety and low irritation: According to the review results of the Cosmetic Ingredient Safety Expert Group, ascorbyl glucoside and its sodium salt are safe in cosmetics[2].
 (4) Slows down aging

General Description

Ascorbyl glucoside is a stable form of vitamin C combined with glucose. When properly formulated and absorbed into skin, it breaks down to ascorbic acid (pure vitamin C).2-O-a-D-Glucopyranosyl-L-ascorbic Acid is a useful cosmetic gel and skin cleanser. Once absorbed, its breakdown to vitamin C is gradual, creating what’s known as a reservoir effect within skin. This leads to longer-lasting benefits.

Biochem/physiol Actions

2-O-a-D-glucopyranosyl-L-ascorbic acid or ascorbyl glucoside functions as a skin whitener and radical scavenger in cosmetics. It is responsible for the bleaching action of bleaching cosmetics. This compound is activated in a manner identical to that of vitamin C. The enzyme present in the epidermal basal membrane, ascorbyl phosphatase, slowly converts 2-O-a-D-glucopyranosyl-L-ascorbic acid into vitamin C, thereby maintaining a high vitamin C level in skin throughout the day.

Side effects

While pure vitamin C can sting and cause mild irritation, there aren't any side effects we know of with ascorbyl glucoside, says Nussbaum. Still, it is an active ingredient for sure, so you can always test out a small amount elsewhere on your skin to make sure you can tolerate it.

References

[1] MARIKO TAKADA. Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos.[J]. International Journal of Molecular Sciences, 2024, 25 24. DOI:10.3390/ijms252413453.
[2] WILBUR JOHNSON. Safety Assessment of Ascorbyl Glucoside and Sodium Ascorbyl Glucoside as Used in Cosmetics.[J]. International Journal of Toxicology, 2025: 5S-16S. DOI:10.1177/10915818241297075.

Ascorbyl glucoside Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Ascorbyl glucoside Suppliers

LoongZe (NanJing) Medicine Chemical Industry CO.,LTD
Tel
025-58392866-05 17766083849
Email
3696999150@qq.com
Country
China
ProdList
28
Advantage
58
Wuxi Jingyao Bio-Technology Co., Ltd.
Tel
0510-88770633 13961738808
Email
jingyaobiotech@126.com
Country
China
ProdList
346
Advantage
55
Changxing Pharmaceutical Co., Ltd.
Tel
0572-6236833 13362221629
Fax
0572-6236733
Email
jianjian6602@163.com
Country
China
ProdList
14
Advantage
58
Zhejiang Invertin Biotechnology Co.,Ltd.td.
Tel
0572-2165030 17369571355
Fax
QQ:1169435659
Email
17369571355@163.com
Country
China
ProdList
58
Advantage
58
Spec-Chem Industry Inc.
Tel
025-84523390 13505162978
Email
sc@specchemind.com
Country
China
ProdList
116
Advantage
58
WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?)
Tel
0571-82358004 13588879771
Email
info@weitai-pharmaceutical.com
Country
China
ProdList
68
Advantage
58
Shandong Haohao Biotechnology Co. , Ltd.
Tel
13953762558
Email
zcy0719@163.com
Country
China
ProdList
35
Advantage
58
ZHENYOU LIAO (WUHAN) BIOTECHNOLOGY CO., LTD.
Tel
18062454418
Email
info@blazinggalaxy.com
Country
China
ProdList
102
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
More
Less

View Lastest Price from Ascorbyl glucoside manufacturers

Jinan Ruitong Biotech Co., Ltd.
Product
Ascorbyl glucoside 129499-78-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1
Release date
2025-09-08
WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?)
Product
Ascorbyl glucoside(AA2G) 129499-78-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20ton
Release date
2025-08-19
Anhuyan (Hainan) Biotechnology Co., LTD
Product
Ascorbyl glucoside 129499-78-1
Price
US $0.00-0.00/g
Min. Order
0.1g
Purity
99%
Supply Ability
1000000t
Release date
2025-06-12

129499-78-1, Ascorbyl glucosideRelated Search:


  • Ascofresh
  • L-Ascorbic acid, 2-O-.alpha.-D-glucopyranosyl-
  • AA-2G
  • ascorbic acid 2-O-glucoside
  • ASCORBYL GLUCOSIDE, ASCORBIC ACID-2- GLUCOSIDE
  • 2-O-A-D-GLUCOPYRANOSYL-L-ASCORBIC ACID
  • L-Ascorbic acid 2-o-alpha-glucoside
  • Pyrido(1,2-A)indol-6(7H)-one, 8,9-dihydro-7-(hydroxy(5-methyl-1H-imidazol-4-yl)methyl)-10-propyl-, (R*,S*)-
  • L-Ascorbic acid, AA-2G
  • ASCORBYL GLUCOSIDE
  • -<small>D</small>-Glucopyranosyl-<small>L</small>-ascorbic Acid
  • 2-<i>O</i>-&alpha
  • L- ascorbic acid 2-
  • 2-O-A-D-GLUCOPYRANOSYL-L-ASCORBIC AC
  • Vitamin C Glucoside
  • Ascorbic acid 2-glucoside, AA2G
  • ASCORBYLGLUCOSIDEPyruvicacid
  • LGB-AA2G
  • Glucosinolate ascorbate
  • Ascorbyl Glucoside Bree
  • 2-O-α-D-Glucopyranosyl-L-ascorbicAcid&gt
  • L-Ascorbic acid, 2-O-α-D-glucopyranosyl-
  • 2-O-α-D-Glucopyranosyl-L-ascorbic Acid
  • Ascorbate glucoside
  • Aa2G/Ascorbyl Glucoside
  • Ascorbic acid 2-glucoside
  • Buy Ascorbyl Glucoside Powder CAS 129499-78-1
  • L-ascorbic acid 2-O-α-glucoside
  • Ascorbyl Glucoside / AA2G
  • 2-O-alpha-D-glucopyranosyl-L-threo-hex-1-enofuranos-3-ulose
  • L-Ascorbic acid, 2-O-a-D-glucopyranosyl-
  • 4-METHYL-2-PENTYL-1,3-DIOXOLANE 1599-49-1
  • 2-O-α-D-Glucopyranosyl-L-ascorbic Acid (AA2G)
  • Ascorbyl-2-Beta-D- Glucoside
  • (R)-5-((S)-1,2-Dihydroxyethyl)-4-hydroxy-3-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)furan-2(5H)-one
  • VCG
  • Ascorbic acid glucoside
  • Ascrobyl Glucoside
  • 129499-78-1
  • 29499-78-1
  • 1294499-78-1
  • 129499-78-1