5-FLUORO-2-IODOBENZYL ALCOHOL
- Product Name
- 5-FLUORO-2-IODOBENZYL ALCOHOL
- CAS No.
- 877264-43-2
- Chemical Name
- 5-FLUORO-2-IODOBENZYL ALCOHOL
- Synonyms
- (5-Fluoro-2-iodophenyl);(5-fluoro-2-iodophenyl)methano;5-Fluoro-2-iodobenzylalcohol97%;(5-Fluoro-2-iodophenyl)Methanol;Benzenemethanol, 5-fluoro-2-iodo-;5-Fluoro-2-iodobenzyl alcohol 97%
- CBNumber
- CB12567317
- Molecular Formula
- C7H6FIO
- Formula Weight
- 252.02
- MOL File
- 877264-43-2.mol
5-FLUORO-2-IODOBENZYL ALCOHOL Property
- storage temp.
- 2-8°C(protect from light)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2906290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PC48326
- Product name
- 5-Fluoro-2-iodobenzylalcohol
- Purity
- 97%
- Packaging
- 250mg
- Price
- $73
- Updated
- 2021/12/16
- Product number
- 2701-K-02
- Product name
- 5-Fluoro-2-iodobenzyl alcohol
- Purity
- 97%
- Packaging
- 250mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- PC48326
- Product name
- 5-Fluoro-2-iodobenzylalcohol
- Purity
- 97%
- Packaging
- 1g
- Price
- $218
- Updated
- 2021/12/16
- Product number
- 2701-K-02
- Product name
- 5-Fluoro-2-iodobenzyl alcohol
- Purity
- 97%
- Packaging
- 1g
- Price
- $240
- Updated
- 2021/12/16
- Product number
- HCH0367394
- Product name
- (5-FLUORO-2-IODOPHENYL)METHANOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.72
- Updated
- 2021/12/16
5-FLUORO-2-IODOBENZYL ALCOHOL Chemical Properties,Usage,Production
Synthesis
52548-63-7
877264-43-2
Step 1: 5-fluoro-2-iodobenzoic acid (5.00 g, 18.80 mmol) was dissolved in tetrahydrofuran (50 mL) and cooled to 0 °C under nitrogen protection. The borane-dimethyl sulfide complex (3.57 mL, 37.60 mmol) was slowly added dropwise under stirring conditions, followed by gradual warming of the reaction mixture to room temperature. The reaction was stirred continuously for 16 hours at room temperature. Upon completion of the reaction, the mixture was carefully poured into ice and quenched by adding 10% aqueous potassium carbonate solution (50 mL). The mixture was extracted with dichloromethane (2 x 50 mL), the organic phases were combined, dried over magnesium sulfate and subsequently concentrated under reduced pressure to give 5-fluoro-2-iodobenzyl alcohol as a colorless solid (4.80 g, 91% yield).1H NMR (400 MHz, CDCl3): δ 7.68 (dd, 1H, J= Hz), 7.19 (dd, 1H, J= Hz), and 6.70 (td, 1H, J= Hz), 4.57 (d, 2H, J= Hz), 1.95 (t, 1H, J= Hz).
References
[1] Advanced Synthesis and Catalysis, 2015, vol. 357, # 14-15, p. 3206 - 3214
[2] Organic Letters, 2018, vol. 20, # 2, p. 345 - 348
[3] Patent: WO2013/132376, 2013, A1. Location in patent: Page/Page column 238
[4] Patent: US2006/52378, 2006, A1. Location in patent: Page/Page column 146
[5] Chemical Communications, 2013, vol. 49, # 31, p. 3254 - 3256
5-FLUORO-2-IODOBENZYL ALCOHOL Preparation Products And Raw materials
Raw materials
Preparation Products
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