ChemicalBook > CAS DataBase List > FMOC-alpha-glutaMine

FMOC-alpha-glutaMine

Product Name
FMOC-alpha-glutaMine
CAS No.
292150-20-0
Chemical Name
FMOC-alpha-glutaMine
Synonyms
Fmoc-D-iso-Gln;Fmoc-D-Igln-OH;Fmoc-DL-Glu-NH2;Fmoc-α-Glutamine;Fmoc-d-isoglutamine;FMOC-alpha-glutaMine;N-Fmoc-D-isoglutamine;Fmoc-alpha-Glutamine, >97%;Fmoc-D-glutamic acid α-amide;FMOC-alpha-glutaMine USP/EP/BP
CBNumber
CB12570982
Molecular Formula
C20H20N2O5
Formula Weight
368.38
MOL File
292150-20-0.mol
More
Less

FMOC-alpha-glutaMine Property

storage temp. 
2-8°C
form 
solid
Appearance
White to off-white Solid
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS020862
Product name
(4R)-5-Amino-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid
Packaging
25 mg
Price
$179
Updated
2025/07/31
TRC
Product number
F680030
Product name
Fmoc-D-Glu-NH2
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
F680030
Product name
Fmoc-D-Glu-NH2
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
F680030
Product name
Fmoc-D-Glu-NH2
Packaging
500mg
Price
$65
Updated
2021/12/16
Chem-Impex
Product number
26456
Product name
Fmoc-D-glutamicacidα-amide,≥98%(HPLC)
Purity
≥98%(HPLC)
Packaging
250MG
Price
$75.71
Updated
2021/12/16
More
Less

FMOC-alpha-glutaMine Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Synthesis

104091-09-0

292150-20-0

General procedure for the synthesis of (R)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-amino-5-oxoglutarate from (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-amino-5-oxopentanedioic acid: Fmoc-D-Glu-OH (59.8 g, 1.0 equiv) was dissolved in anhydrous tetrahydrofuran (THF, 324 mL). N,N'-dicyclohexylcarbodiimide (DCC, 40.1 g, 1.2 eq.) was added slowly with stirring under cooling in an ice-water bath. The reaction mixture was gradually warmed to room temperature and stirring was continued for 8 hours to produce a 1,3-dicyclohexylurea (DCU) precipitate. The precipitate was removed by filtration and washed with a small amount of THF. Subsequently, dry ammonia was passed into the filtrate under NaCl-ice bath cooling and stirring was continued for 1.5 h until no white solid precipitated. After standing for 30 min, a small amount of methanol (MeOH) was added to dissolve the solid. The mixture was again cooled in an ice water bath and the pH was adjusted to 2-3 by slow dropwise addition of 2.0 N HCl solution. the solvent was removed by concentration under reduced pressure. The resulting solid was dissolved in ethyl acetate (AcOEt) and washed sequentially with dilute HCl, saturated aqueous NaHCO3 solution and deionized water. The organic layers were separated, combined and dried with anhydrous magnesium sulfate (MgSO4) overnight. After filtration, the solvent was evaporated under reduced pressure and the residue was recrystallized by ethyl acetate-cyclohexane system. After filtration, 46.5 g of the target product was obtained in 78% yield. The product had a melting point of 204-205 °C and a specific optical rotation [α] = -4.2° (c = 10 mg/mL, DMF).1H-NMR (500 MHz, DMSO-d6) δ: 7.88 (2H, d, J = 8.0 Hz), 7.72 (2H, m), 7.42 (2H, m), 7.40 (1H, m), 7.40 (1H, br. s), 7.32 (2H, m), 7.02 (1H, br. s), 4.27 (2H, m), 4.20 (1H, m), 3.93 (1H, dd, J = 13.5, 8.5 Hz), 2.25 (2H, m), 1.89 (1H, m), 1.73 (1H, m).13C-NMR (125 MHz, DMSO-d6 ) δ: 173.9, 173.4, 155.9, 143.8, 140.7, 127.6, 127.0, 125.3, 120.0, 65.6, 53.8, 46.6, 30.4, 27.2. ESI-MS: m/z 369.03 [M + H]+, 759.98 [2M + Na]+. HR-MS (TOF) : m/z 369.1448 [M + H]+ (calculated value: 369.1449), 759.2623 [2M + Na]+ (calculated value: 759.2625), molecular formula C20H20N2O5.

References

[1] Patent: EP2612857, 2017, B1. Location in patent: Paragraph 0102-0107

FMOC-alpha-glutaMine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

FMOC-alpha-glutaMine Suppliers

China 77 India 2 United States 5 Global 84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
ShenZhen InnoSyn Biotech Co.,Ltd
Tel
0755-28351685 18503098468
Fax
+86-755-28466854
Email
innosyn@163.com
Country
China
ProdList
602
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6874
Advantage
55
Shenzhen Chim Biotech Co., Ltd.
Tel
13692196024
Fax
0755-28364769
Email
sales@chimchem.com
Country
China
ProdList
501
Advantage
55
Shanghai GL Peptide Ltd.
Tel
+86-21-61263340; 17609490614 13764994101
Fax
021-61263399
Email
fisherwang@glschina.com
Country
China
ProdList
8258
Advantage
55
Wuxi Asia Peptide Biotechnology Limited Company
Tel
0510-83583050 13771062561
Fax
0510-83583039
Email
willsun@peptide-search.com
Country
China
ProdList
6716
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10110
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Wuhan Wsem Biological Co., Ltd.
Tel
027-83778876 13667159345
Fax
027-83778876
Email
13667159345@163.com
Country
China
ProdList
1997
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Shanghai Chain peptide Biological Co., Ltd.
Tel
+86 18516118859
Fax
+86 (21) 2096 2272
Email
sales@chainpeptide.com
Country
CHINA
ProdList
419
Advantage
58
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58
Zhuzhou focus pharmaceutical technology co., LTD
Tel
+86-13776644403
Email
robert@focuspharma.cc
Country
China
ProdList
2459
Advantage
58
Kanghua (Shanghai) New Drug Development Co., Ltd.
Tel
021-61263370 18901917034
Email
xingli@glbiochem.com
Country
China
ProdList
5637
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
Shanghai Jifeng Biotechnology Co., Ltd.
Tel
021-61263377 15023907684
Fax
021-61263399
Email
15800684150@163.com
Country
China
ProdList
8131
Advantage
58
Shanghai UCHEM Inc.
Tel
+862156762820 +86-13564624040
Email
sales@myuchem.com
Country
China
ProdList
8460
Advantage
58
Hunan Jibang Biological Technology Co., LTD
Tel
+8613776644403
Email
sales02@kingboomtech.com
Country
China
ProdList
1804
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
20284
Advantage
58
GL Biochem(Binhai) Ltd.
Tel
+86-021-61263370 +8615301650015
Email
wuqiuyan@glschina.com
Country
China
ProdList
2975
Advantage
58
Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658 18135795563
Fax
QQ:2885349392
Email
2885349392@qq.com
Country
China
ProdList
9989
Advantage
58
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
chemwill_asia@126.com
Country
CHINA
ProdList
23912
Advantage
58
Binhai gill polypeptide co. LTD
Tel
021-61263389 13524856427
Fax
WeChat630417570
Email
Joetang@glschina.com
Country
China
ProdList
10000
Advantage
58
Shanghai Anhua Biotechnology Co., Ltd.
Tel
021-61263375 18168859245
Country
China
ProdList
5958
Advantage
58
Hubei xin bonus chemical co. LTD
Tel
86-13657291602
Fax
027-59338440
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
22963
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39927
Advantage
58
Wuxi maimo topp biotechnology co., LTD
Tel
13771048682 15061806929
Email
alice@mimotopes.cn
Country
China
ProdList
5796
Advantage
58
Jiangsu Hongmin Pharmaceutical Co., Ltd.
Tel
18221292452
Email
fannieliu@glschina.com
Country
China
ProdList
6798
Advantage
58
Jiangsu Jitai Peptide Technology Co., Ltd.
Tel
0515-8085-5066 13770132022
Email
sales05@gtaipeptide.com
Country
China
ProdList
2675
Advantage
58
Jiangsu Shengkang Meixiang Technology Co., Ltd.
Tel
18217475093
Email
1615396342@qq.com
Country
China
ProdList
4309
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Gill polypeptide biopharmaceutical (dalian) co., LTD
Tel
021-61263455 13167021076
Email
amy@glschina.com
Country
China
ProdList
9736
Advantage
58
Taizhou Nanfeng Pharmaceutical Research Institute
Tel
nanfengdrug@163.com; 18616377689
Email
nanfengdrug@163.com
Country
China
ProdList
20009
Advantage
58
Neostar United (Changzhou) Industrial Co., Ltd.
Tel
+86-0519-85551759 +8613506123987
Fax
+0086-519-85557389
Email
marketing1@neostarunited.com
Country
China
ProdList
8830
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
DONBOO AMINO ACID COMPANY
Tel
+8618051385538
Email
donboo@donboo.com
Country
China
ProdList
9363
Advantage
58
cjbscvictory
Tel
13348960310
Email
3003867561@qq.com
Country
China
ProdList
10503
Advantage
58
Hubei Yuanmeng Biotechnology Co., Ltd
Tel
027-68897569 18120462897
Fax
027-68897569
Email
fiona@yuanmengbio.com
Country
China
ProdList
4657
Advantage
58
Shanghai kadel chemical technology co., LTD
Tel
021-4007787-550 400-7787-550
Email
2850202386@qq.com
Country
China
ProdList
10582
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
29668
Advantage
58
More
Less

View Lastest Price from FMOC-alpha-glutaMine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
FMOC-alpha-glutaMine 292150-20-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25
Career Henan Chemical Co
Product
FMOC-alpha-glutaMine 292150-20-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-15

292150-20-0, FMOC-alpha-glutaMineRelated Search:

Polyglutamic acid

  • FMOC-alpha-glutaMine
  • FMOC-D-ISOGLN-OH(FMOC-D-GLU-NH2)
  • (4R)-5-Amino-4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-5-oxopentanoic acid
  • Fmoc-D-glutamic acid α-amide≥ 99% (HPLC)
  • Fmoc-D-Igln-OH
  • N-Fmoc-D-isoglutamine
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl D-isoGln-OH
  • Fmoc-D-iso-Gln
  • (R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-amino-5-oxopentanoicacid
  • 4-Carbamoyl-4-(9H-fluoren-9-ylmethoxycarbonylamino)-butyric acid
  • 5-amino-4-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-5-oxopentanoic acid
  • (4R)-4-carbamoyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
  • Fmoc-alpha-Glutamine, >97%
  • Pentanoic acid, 5-amino-4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-5-oxo-, (4R)-
  • (4R)-5-Amino-4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-5-oxopentaoic acid
  • Fmoc-DL-Glu-NH2
  • 5-amino-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxopentanoicaci
  • FMOC-alpha-glutaMine USP/EP/BP
  • Fmoc-D-glutamic acid α-amide
  • 5-amino-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxopentanoic acid
  • Fmoc-d-isoglutamine
  • N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-alpha-glutamine
  • Fmoc-α-Glutamine
  • Fmoc-D-glutamic acid α-amide, CAS 292150-20-0
  • 292150-20-0