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Polyglutamic acid

Product Name
Polyglutamic acid
CAS No.
25513-46-6
Chemical Name
Polyglutamic acid
Synonyms
γ-PGA;Y-Polyglutamic Acid;y-PGA;γ-Polyglutamic acid;alpha-l-glutamicacidpolymer;Poly-γ-Glutamic Acid(γ-PGA);POLY-L;Polyglutamicaci;poly-l-glutamate;γ- polyglutamate
CBNumber
CB2132778
Molecular Formula
C5H9NO4
Formula Weight
147.13
MOL File
25513-46-6.mol
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Polyglutamic acid Property

storage temp. 
−20°C
InChI
InChI=1/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/s3
InChIKey
WHUUTDBJXJRKMK-ZJPLZJKBNA-N
SMILES
[C@@H](N)(C(=O)O)CCC(=O)O |&1:0,r|
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Safety

WGK Germany 
3
RTECS 
MA1700000
3-10
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0043360
Product name
γ-Polyglutamicacidγ-PGA
Packaging
10g
Price
$115
Updated
2021/12/16
ChemScene
Product number
CS-0043360
Product name
γ-Polyglutamicacidγ-PGA
Packaging
25g
Price
$230
Updated
2021/12/16
Labseeker
Product number
SC-19546
Product name
POLY-L-GLUTAMICACID
Purity
分子量150万
Packaging
100g
Price
$400
Updated
2021/12/16
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Polyglutamic acid Chemical Properties,Usage,Production

Description

Polyglutamic acid (PGA), a poly amino acid produced by Bacillus spp. is a naturally occurring anionic, water-soluble, biodegradable, non-toxic, viscous, edible biopolymer containing D and L-glutamic acid residues with different industrial applications.

Uses

Polyglutamic acid is commonly used in cosmetics as a powerful humectant for moisturising the skin. It is ideal for people with dry or dehydrated skin and may help to reduce the appearance of fine lines and wrinkles. Polyglutamic acid is also used in the food industry and has the ability to improve taste and flavour. In addition, Polyglutamic acid is an environmentally friendly biomaterial that can be used as a drug carrier/delivery agent and as a contrast agent.

Definition

ChEBI: A macromolecule composed of repeating gamma-linked L-glutamyl units.

Application

Polyglutamic acid is considered a promising bio-based chemical and is already widely used in the food, medical, and wastewater industries due to its biodegradable, non-toxic, and non-immunogenic properties.

Preparation

The Preparation method of Polyglutamic acid is as follows:poplar sawdust was used to produce Polyglutamic acid. Poplar sawdust was treated with acid and then hydrolyzed with cellulose. The enzymatic hydrolysate was used to produce Polyglutamic acid. Through single factor and orthogonal experiments, the optimum enzymatic conditions were determined as follows: solid-liquid ratio 1:5, enzyme amount 22 FPU/g, pH 5.0 and 53 min. Under the enzymatic hydrolysate medium, the Polyglutamic acid yield reached 30.87 ± 0.44 g/L, which was 5.11% higher than that in glucose medium (29.37 ± 0.43 g/L). In addition, the amount of glucose added to the medium was reduced, which realized the comprehensive utilization of various sugars in sawdust enzymatic hydrolysate.

benefits

The primary benefit of polyglutamic acid is its impressive ability to hydrate skin. Because it’s a polymer, it forms a flexible, smooth, moisture-binding film on skin’s surface. This film helps skin keep moisture in its surface layers, even in conditions of low humidity, making polyglutamic acid an effective humectant. In addition to its abilities to aid skin in moisture retention, polyglutamic acid soothes and helps increase the production of natural moisturizing factors (NMF) in skin, which contributes to having a healthier barrier and balanced hydration. Polyglutamic acid hydrates skin but also performs other roles as well including wrinkle reduction, balancing the effects of chronic sun exposure and enhancing wound healing.

Side effects

Polyglutamic acid is generally considered safe and allergic reaction side effects are rare, which may result in itching, swelling, redness, burning sensation or blisters. Before applying Polyglutamic acid to your face, you can perform a patch test to ensure that you are tolerating this ingredient well.

Toxicology

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher

Polyglutamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Polyglutamic acid Suppliers

Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
Kono Chem Co., Ltd
Tel
029-86107037-8014 18292830413
Email
info@konochemical.com
Country
China
ProdList
536
Advantage
58
Hangzhou Linran Biotechnology Co. LTD
Tel
0571-18067987-92 18067987892
Fax
0571-88772395
Email
2543558860@qq.com
Country
China
ProdList
146
Advantage
58
Wuhan kamik Technology Co., Ltd
Tel
18062587608
Email
201981259@qq.com
Country
China
ProdList
7716
Advantage
58
Wuhan DKY Technology Co.,Ltd.
Tel
027-81302411 15377658509
Email
zs@dkybpc.com
Country
China
ProdList
2098
Advantage
58
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7583
Advantage
55
Beijing Taiya Jie Technology Development Co., Ltd.
Tel
021-33690831-8001 13552411790
Fax
021-33690831
Email
postmaster@tyjchem.cn
Country
China
ProdList
1542
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
021-50430803 18017383231
Fax
qq:2817624287
Email
983544897@qq.com
Country
China
ProdList
9352
Advantage
55
Syncozymes (Shanghai) Co.,Ltd.
Tel
021-68187180-819 13681683526
Fax
021-68187179
Email
lchen@syncozymes.com
Country
China
ProdList
186
Advantage
55
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View Lastest Price from Polyglutamic acid manufacturers

Jinan Finer Chemical Co., Ltd
Product
γ-Polyglutamic acid 25513-46-6
Price
US $5.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500mt/year
Release date
2023-03-24
Hebei Yime New Material Technology Co., Ltd.
Product
Polyglutamic Acid 25513-46-6
Price
US $450.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg
Release date
2023-11-16
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
Polyglutamic acid 25513-46-6
Price
US $20.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
200000kg
Release date
2024-04-24

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