(1alpha,3beta,22R)-3-[(6-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy]-1,22-dihydroxyergosta-5,24-dien-26-oic acid delta-lactone

(1alpha,3beta,22R)-3-[(6-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy]-1,22-dihydroxyergosta-5,24-dien-26-oic acid delta-lactone Property

Boiling point:

935.2±65.0 °C(Predicted)

Density 

1.39

storage temp. 

2-8°C

solubility 

DMSO: Soluble: = 10 mg/ml

pka

12.89±0.70(Predicted)

form 

solid

Hazard and Precautionary Statements (GHS)

(1alpha,3beta,22R)-3-[(6-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy]-1,22-dihydroxyergosta-5,24-dien-26-oic acid delta-lactone Chemical Properties,Usage,Production

Uses

Withanoside V is a withanolide derivative isolated from the roots of Withania somnifera. Withania somnifera L. Dunal (Solanaceae), also known as ''ashwagandha'' in Sanskrit and as ''Indian ginseng'', is used widely in Ayurvedic medicine as a nerve tonic and memory enhancer, with antiaging, antistress, immunomodulatory and antioxidant properties.

References

[1] BOLLEDDULA JAYAPRAKASAM  Muraleedharan G N  Gale A Strasburg. Potent lipid peroxidation inhibitors from Withania somnifera fruits[J]. Tetrahedron, 2004, 60 13: Pages 3109-3121. DOI: 10.1016/j.tet.2004.01.016
[2] SHREYA DUBEY  Rajagopal S  Monika Kallubai. Improving the inhibition of β-amyloid aggregation by withanolide and withanoside derivatives[J]. International Journal of Biological Macromolecules, 2021, 173: Pages 56-65. DOI: 10.1016/j.ijbiomac.2021.01.094
[3] RAJKUMAR SINGH KALRA. COVID19-inhibitory activity of withanolides involves targeting of the host cell surface receptor ACE2: insights from computational and biochemical assays.[J]. Journal of Biomolecular Structure & Dynamics, 2022: 7885-7898. DOI: 10.1080/07391102.2021.1902858