ChemicalBook > CAS DataBase List > H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2

H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2

Product Name: H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2
CAS No.: 100853-58-5
Chemical Name: H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2
Synonyms: WIPTIDE;PKI (5-22), AMIDE;TTYADFIASGRTGRRNAI-NH2;PKA INHIBITOR (5-22) AMIDE;PROTEIN KINASE A INHIBITOR (5-22) AMIDE;CAMP DEPENDENT PK INHIBITOR (5-22) AMIDE;PKI-ALPHA (5-22) AMIDE (HUMAN, MOUSE, RABBIT, RAT);CAMP-DEPENDENT PROTEIN KINASE INHIBITOR (5-22) AMIDE;PKI-a (5-22) aMide (huMan, Mouse, rabbit, rat), Wiptide;cAMP-Dependent Protein Kinase Inhibitor (5-22), amide, Wiptide
CBNumber: CB1259003
Molecular Formula: C84H137N29O26
Formula Weight: 1969.17
MOL File: 100853-58-5.mol

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H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2 Property

Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: -15°C

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FC108932
Product name: cAMP-Dependent Protein Kinase Inhibitor-a (5-22) amide (human, mouse, rabbit, rat)
Packaging: 1mg
Price: $118
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC108932
Product name: cAMP-Dependent Protein Kinase Inhibitor-a (5-22) amide (human, mouse, rabbit, rat)
Packaging: 2mg
Price: $205
Updated: 2021/12/16

AK Scientific

Product number: 4459EC
Product name: (3S)-4-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S,3R)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-4-Amino-1-[[(2S)-1-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-4-oxobutanoicacid
Packaging: 1mg
Price: $209
Updated: 2021/12/16

AK Scientific

Product number: 4459EC
Product name: (3S)-4-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S,3R)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-4-Amino-1-[[(2S)-1-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-4-oxobutanoicacid
Packaging: 2mg
Price: $326
Updated: 2021/12/16

Chem-Impex

Product number: 33016
Product name: H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2
Packaging: 5MG
Price: $335.46
Updated: 2021/12/16

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H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2 Chemical Properties,Usage,Production

Uses

PKI(5-22)amide is the active inhibitory fragment of the inhibitor of the cyclic AMP-dependent protein kinase (PKA). PKI(5-22)amide inhibits PKA activation, but fails to attenuate homologous desensitization of CRF1 receptors[1][2].

References

[1] Dautzenberg FM, et al. GRK3 mediates desensitization of CRF1 receptors: a potential mechanism regulating stress adaptation. Am J Physiol Regul Integr Comp Physiol. 2001 Apr;280(4):R935-46. DOI:10.1152/ajpregu.2001.280.4.R935
[2] Reed J, et al. Conformational analysis of PKI(5-22)amide, the active inhibitory fragment of the inhibitor protein of the cyclic AMP-dependent protein kinase. Biochem J. 1989 Dec 1;264(2):371-80. DOI:10.1042/bj2640371

H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2 manufacturers

Career Henan Chemical Co

Product: H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2 100853-58-5
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2020-03-05

100853-58-5, H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2Related Search:

H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP-OH CAMP-DEPENDENT PROTEIN KINASE INHIBITOR (5-24) AMIDE PKA Inhibitor Fragment (6-22) amide H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2 PROTEIN KINASE A INHIBITOR FRAGMENT 5-24 AMIDE TRIFLUOROACETATE SALT ASN-TYR-PRO-LEU-GLU-LEU-TYR-GLU-ARG-VAL-ARG-THR-GLY-CYS PROTEIN KINASE C (19-35) H-VAL-ARG-LYS-ARG-THR-LEU-ARG-ARG-LEU-OH H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH H-ARG-PHE-ALA-ARG-LYS-GLY-ALA-LEU-ARG-GLN-LYS-ASN-VAL-HIS-GLU-VAL-LYS-ASN-OH

THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2

PKA INHIBITOR (5-22) AMIDE

PKI (5-22), AMIDE

PKI-ALPHA (5-22) AMIDE (HUMAN, MOUSE, RABBIT, RAT)

PROTEIN KINASE A INHIBITOR (5-22) AMIDE

WIPTIDE

TTYADFIASGRTGRRNAI-NH2

H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2

CAMP DEPENDENT PK INHIBITOR (5-22) AMIDE

CAMP-DEPENDENT PROTEIN KINASE INHIBITOR (5-22) AMIDE

CAMP-DEPENDENT PROTEIN KINASE INHIBITOR-ALPHA (5-22) AMIDE (HUMAN, MOUSE, RABBIT, RAT)

THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-HIS-ASP: TTYADFIASGRTGRRNAIHD

cAMP-Dependent Protein Kinase Inhibitor (5-22), amide, Wiptide

cAMP-Dependent Protein Kinase Inhibitor-a (5-22) aMide (huMan, Mouse, rabbit, rat)

PKI-a (5-22) aMide (huMan, Mouse, rabbit, rat), Wiptide

L-Isoleucinamide, L-threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-α-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-L-arginyl-L-arginyl-L-asparaginyl-L-alanyl- (9CI)

cAMP-Dependent Protein Kinase Inhibitor-α (5-22) amide (human, mouse, rabbit, rat)

100853-58-5

C84H137N29O26

peptide