H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH

Product Name: H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH
CAS No.: 136795-05-6
Chemical Name: H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH
Synonyms: RFARKGSLRQKNV;[SER25]-PKC (19-31);[SER25]-PROTEIN KINASE C (19-31);PROTEIN KINASE C [SER-25] (19-31);[SER 25]-PROTEIN KINASE C FRAGMENT 19-31;7:PN:JP2006076967 SEQID:7 unclaimed protein;ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL;H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH;Protein Kinase C Fragment [Ser25] Protein Kinase C(19-31);L-Valine, L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysylglycyl-L-seryl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparaginyl-
CBNumber: CB5140213
Molecular Formula: C67H118N26O17
Formula Weight: 1559.82
MOL File: 136795-05-6.mol

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H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH Property

storage temp.: −20°C
solubility: insoluble in EtOH; ≥155.9 mg/mL in DMSO; ≥65.2 mg/mL in H2O
form: White to off-white powder.

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: A1033
Product name: [Ser25]ProteinKinaseC(19-31)
Packaging: 5mg
Price: $135
Updated: 2021/12/16

ApexBio Technology

Product number: A1033
Product name: [Ser25]ProteinKinaseC(19-31)
Packaging: 1mg
Price: $45
Updated: 2021/12/16

ApexBio Technology

Product number: A1033
Product name: [Ser25]ProteinKinaseC(19-31)
Packaging: 10mg
Price: $225
Updated: 2021/12/16

ApexBio Technology

Product number: A1033
Product name: [Ser25]ProteinKinaseC(19-31)
Packaging: 25mg
Price: $315
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0000238
Product name: [SER25] - PKC (19 - 31)
Purity: 95.00%
Packaging: 1MG
Price: $622.15
Updated: 2021/12/16

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H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH Chemical Properties,Usage,Production

Uses

[Ser25] Protein Kinase C (19-31) is a substrate of protein kinase C (PKC) (Km: 0.3 μM). [Ser25] Protein Kinase C (19-31) is derived from the pseudo-substrate regulatory domain of PKCα (19-31) with a Serine at position 25 replacing the wild-type Alanine[1].

Biological Activity

protein kinase c (19-31), (c67h118n26o17), a peptide with the sequence h-arg-phe-ala-arg-lys-gly-ser-leu-arg-gln-lys-asn-val-oh, mw= 1559.82. this peptide derived from the pseudo-substrate regulatory domain of pkca (residues 19-31) with a serine at position 25 replacing the wild-type alanine, it was used as protein kinase c substrate peptide for testing the protein kinase c activity.protein kinase c also known as pkc, is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins. pkca has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and ca2+ handling in myocytes.figure1 formula of [ser25] protein kinase c (19-31)figure2 signaling pathway of protein kinase c1. mellor h, parker pj (1998). "the extended protein kinase c superfamily". biochem. j.. 332 ( pt 2): 281–922. nishizuka y (1995). "protein kinase c and lipid signaling for sustained cellular responses" (abstract). faseb j. 9 (7): 484–96.3. vicente micol. correlation between protein kinase c an activity and membrane phase behavior. departamento de bioquı´mica y biologı´a molecular

References

[1] Wilder PT, et al. S100B(betabeta) inhibits the protein kinase C-dependent phosphorylation of a peptide derived from p53 in a Ca2+-dependent manner. Protein Sci. 1998 Mar;7(3):794-8. DOI:10.1002/pro.5560070330

H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH Suppliers

China 72 France 1 Switzerland 2 The Netherlands 1 United States 11 Global 87

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136795-05-6, H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OHRelated Search:

LYS(BIOTIN)-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH ISOTOCIN [SER2]-NEUROMEDIN C H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-HIS-GLU-VAL-LYS-ASN-OH (Ser8)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) PROTEIN KINASE C (19-31) H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH H-ASN-VAL-OH ASN-TYR-PRO-LEU-GLU-LEU-TYR-GLU-ARG-VAL-ARG-THR-GLY-CYS H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2

[SER 25]-PROTEIN KINASE C FRAGMENT 19-31

PROTEIN KINASE C [SER-25] (19-31)

RFARKGSLRQKNV

H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH

ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL

[SER25]-PKC (19-31)

[SER25]-PROTEIN KINASE C (19-31)

L-Valine, L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysylglycyl-L-seryl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparaginyl-

7:PN:JP2006076967 SEQID:7 unclaimed protein

Protein Kinase C Fragment [Ser25] Protein Kinase C(19-31)

136795-05-6

C67H118N26O17

Serine/Threonine Kinase Substrates

Protein Kinase C (PKC)

Kinase/Phosphatase Biology

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Neuroscience

Enzyme Substrates

Protein Kinase C (PKC)Peptides for Cell Biology

Protein Kinase CSerine/Threonine Kinase Biology

Protein Kinase Related Peptides

Protein Kinase Substrates

Serine/Threonine Kinase Substrates

Substrates by Enzyme

peptide