ChemicalBook > CAS DataBase List > H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH

H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH

Product Name
H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH
CAS No.
136795-05-6
Chemical Name
H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH
Synonyms
RFARKGSLRQKNV;[SER25]-PKC (19-31);[SER25]-PROTEIN KINASE C (19-31);PROTEIN KINASE C [SER-25] (19-31);[SER 25]-PROTEIN KINASE C FRAGMENT 19-31;7:PN:JP2006076967 SEQID:7 unclaimed protein;ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL;H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH;Protein Kinase C Fragment [Ser25] Protein Kinase C(19-31);L-Valine, L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysylglycyl-L-seryl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparaginyl-
CBNumber
CB5140213
Molecular Formula
C67H118N26O17
Formula Weight
1559.82
MOL File
136795-05-6.mol
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H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH Property

storage temp. 
−20°C
solubility 
insoluble in EtOH; ≥155.9 mg/mL in DMSO; ≥65.2 mg/mL in H2O
form 
White to off-white powder.
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J66676
Product name
[Ser<sup>2</sup><sup>5</sup>] Protein Kinase C (19-31)
Packaging
1mg
Price
$163
Updated
2021/12/16
Alfa Aesar
Product number
J66676
Product name
[Ser<sup>2</sup><sup>5</sup>] Protein Kinase C (19-31)
Packaging
0.5mg
Price
$79.1
Updated
2021/12/16
ApexBio Technology
Product number
A1033
Product name
[Ser25]ProteinKinaseC(19-31)
Packaging
5mg
Price
$135
Updated
2021/12/16
ApexBio Technology
Product number
A1033
Product name
[Ser25]ProteinKinaseC(19-31)
Packaging
1mg
Price
$45
Updated
2021/12/16
ApexBio Technology
Product number
A1033
Product name
[Ser25]ProteinKinaseC(19-31)
Packaging
10mg
Price
$225
Updated
2021/12/16
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H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH Chemical Properties,Usage,Production

Biological Activity

protein kinase c (19-31), (c67h118n26o17), a peptide with the sequence h-arg-phe-ala-arg-lys-gly-ser-leu-arg-gln-lys-asn-val-oh, mw= 1559.82. this peptide derived from the pseudo-substrate regulatory domain of pkca (residues 19-31) with a serine at position 25 replacing the wild-type alanine, it was used as protein kinase c substrate peptide for testing the protein kinase c activity.protein kinase c also known as pkc, is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins. pkca has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and ca2+ handling in myocytes.figure1 formula of [ser25] protein kinase c (19-31)figure2 signaling pathway of protein kinase c1. mellor h, parker pj (1998). "the extended protein kinase c superfamily". biochem. j.. 332 ( pt 2): 281–922. nishizuka y (1995). "protein kinase c and lipid signaling for sustained cellular responses" (abstract). faseb j. 9 (7): 484–96.3. vicente micol. correlation between protein kinase c an activity and membrane phase behavior. departamento de bioquı´mica y biologı´a molecular

H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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136795-05-6, H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OHRelated Search:


  • [SER 25]-PROTEIN KINASE C FRAGMENT 19-31
  • PROTEIN KINASE C [SER-25] (19-31)
  • RFARKGSLRQKNV
  • H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH
  • ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL
  • [SER25]-PKC (19-31)
  • [SER25]-PROTEIN KINASE C (19-31)
  • L-Valine, L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysylglycyl-L-seryl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparaginyl-
  • 7:PN:JP2006076967 SEQID:7 unclaimed protein
  • Protein Kinase C Fragment [Ser25] Protein Kinase C(19-31)
  • 136795-05-6
  • C67H118N26O17
  • Serine/Threonine Kinase Substrates
  • Protein Kinase C (PKC)
  • Kinase/Phosphatase Biology
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Neuroscience
  • Enzyme Substrates
  • Protein Kinase C (PKC)Peptides for Cell Biology
  • Protein Kinase CSerine/Threonine Kinase Biology
  • Protein Kinase Related Peptides
  • Protein Kinase Substrates
  • Serine/Threonine Kinase Substrates
  • Substrates by Enzyme
  • peptide