ChemicalBook > CAS DataBase List > H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH

H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH

Product Name: H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH
CAS No.: 136795-05-6
Chemical Name: H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH
Synonyms: RFARKGSLRQKNV;[SER25]-PKC (19-31);[SER25]-PROTEIN KINASE C (19-31);PROTEIN KINASE C [SER-25] (19-31);[SER 25]-PROTEIN KINASE C FRAGMENT 19-31;7:PN:JP2006076967 SEQID:7 unclaimed protein;ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL;H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH;Protein Kinase C Fragment [Ser25] Protein Kinase C(19-31);L-Valine, L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysylglycyl-L-seryl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparaginyl-
CBNumber: CB5140213
Molecular Formula: C67H118N26O17
Formula Weight: 1559.82
MOL File: 136795-05-6.mol

Less

H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH Property

storage temp.: −20°C
solubility: insoluble in EtOH; ≥155.9 mg/mL in DMSO; ≥65.2 mg/mL in H2O
form: White to off-white powder.

Less

Safety

WGK Germany: 3

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

ApexBio Technology

Product number: A1033
Product name: [Ser25]ProteinKinaseC(19-31)
Packaging: 5mg
Price: $135
Updated: 2021/12/16

ApexBio Technology

Product number: A1033
Product name: [Ser25]ProteinKinaseC(19-31)
Packaging: 1mg
Price: $45
Updated: 2021/12/16

ApexBio Technology

Product number: A1033
Product name: [Ser25]ProteinKinaseC(19-31)
Packaging: 10mg
Price: $225
Updated: 2021/12/16

ApexBio Technology

Product number: A1033
Product name: [Ser25]ProteinKinaseC(19-31)
Packaging: 25mg
Price: $315
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0000238
Product name: [SER25] - PKC (19 - 31)
Purity: 95.00%
Packaging: 1MG
Price: $622.15
Updated: 2021/12/16

Less

H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH Chemical Properties,Usage,Production

Uses

[Ser25] Protein Kinase C (19-31) is a substrate of protein kinase C (PKC) (Km: 0.3 μM). [Ser25] Protein Kinase C (19-31) is derived from the pseudo-substrate regulatory domain of PKCα (19-31) with a Serine at position 25 replacing the wild-type Alanine[1].

Biological Activity

protein kinase c (19-31), (c67h118n26o17), a peptide with the sequence h-arg-phe-ala-arg-lys-gly-ser-leu-arg-gln-lys-asn-val-oh, mw= 1559.82. this peptide derived from the pseudo-substrate regulatory domain of pkca (residues 19-31) with a serine at position 25 replacing the wild-type alanine, it was used as protein kinase c substrate peptide for testing the protein kinase c activity.protein kinase c also known as pkc, is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins. pkca has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and ca2+ handling in myocytes.figure1 formula of [ser25] protein kinase c (19-31)figure2 signaling pathway of protein kinase c1. mellor h, parker pj (1998). "the extended protein kinase c superfamily". biochem. j.. 332 ( pt 2): 281–922. nishizuka y (1995). "protein kinase c and lipid signaling for sustained cellular responses" (abstract). faseb j. 9 (7): 484–96.3. vicente micol. correlation between protein kinase c an activity and membrane phase behavior. departamento de bioquı´mica y biologı´a molecular

References

[1] Wilder PT, et al. S100B(betabeta) inhibits the protein kinase C-dependent phosphorylation of a peptide derived from p53 in a Ca2+-dependent manner. Protein Sci. 1998 Mar;7(3):794-8. DOI:10.1002/pro.5560070330

H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH Preparation Products And Raw materials

Raw materials

Preparation Products

Less

H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH Suppliers

China 72 France 1 Switzerland 2 The Netherlands 1 United States 11 Global 87

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
Fax: 0551-65326641
Email: info@cellmano.com
Country: China
ProdList: 1010
Advantage: 55

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29759
Advantage: 68

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5501
Advantage: 55

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 4802
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7408
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 0571-88211921
Email: sales1@gotopbio.com
Country: CHINA
ProdList: 2609
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 18108052721
Email: 2850505130@qq.com
Country: China
ProdList: 5167
Advantage: 58

Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
Fax: 0551-65326641
Email: info@cellmano.com
Country: China
ProdList: 995
Advantage: 58

Nanjing chengqimei Biotechnology Co., Ltd

Tel: 19850819832
Email: 2173594524@qq.com
Country: China
ProdList: 2638
Advantage: 58

Gill polypeptide biopharmaceutical (dalian) co., LTD

Tel: 021-61263455 13167021076
Email: amy@glschina.com
Country: China
ProdList: 9736
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 15397062932
Email: sales1@gotopbio.com
Country: China
ProdList: 2923
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

TCI (Shanghai) Chemical Trading Co., Ltd.

Tel: 021-61109150
Fax: 021-61105897
Email: sales@tcisct.com
Country: China
ProdList: 29668
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 13675144456
Email: alan.chow@synzest.com
Country: China
ProdList: 9470
Advantage: 58

Nanjing Yuanpeptide Biotech Co.，Ltd.

Tel: 18168071971
Email: support@yuan-peptide.com
Country: China
ProdList: 2983
Advantage: 58

Chengdu Jinglin Biotechnology Co., Ltd.

Tel: 17711399154
Email: 3211919385@qq.com
Country: China
ProdList: 1815
Advantage: 58

Shaoxing Junyu Biotechnology Co., LTD

Tel: 0571-0571-88211921 19105816207
Email: sales4@gotopbio.com
Country: China
ProdList: 5144
Advantage: 58

Hangzhou Sinoda Pharmaceutical Technology Co. LTD

Tel: 0571-87213919 17306812703
Email: 3007955328@qq.com
Country: China
ProdList: 6979
Advantage: 58

Hangzhou Baige Pharmaceutical Technology Co. , Ltd.

Tel: 0571-85350119 15888826472
Email: 15888826472@163.com
Country: China
ProdList: 2729
Advantage: 58

Shanghai HongTide Biotechnology Co.,Ltd.

Tel: 15318089928
Email: alex@hanhonggroup.com
Country: China
ProdList: 4604
Advantage: 58

Combio (Suzhou) Ltd.

Tel: 17751201929
Email: office@combiosz.com
Country: China
ProdList: 3000
Advantage: 58

https://hanhongsci.com/

Tel: 021-54306202 18917919676
Email: info@hanhongsci.com
Country: China
ProdList: 29995
Advantage: 58

Shandong Mopai Biotechnology Co., Ltd

Tel: 13053322091
Email: admin@mopaikeji.com
Country: China
ProdList: 5830
Advantage: 58

Nanjing Yushengkang Biotechnology Co., Ltd

Tel: 13327808530
Email: 2670965693@qq.com
Country: China
ProdList: 2179
Advantage: 58

Zhejiang Jiekun Biotechnology Co., Ltd

Tel: 0571-88211951 13735575465
Email: sales1@gotopbio.com
Country: China
ProdList: 4880
Advantage: 58

Taiyuan Bailihengkang Biotechnology Co., Ltd

Tel: 19135651983
Email: 18611134419@163.com
Country: China
ProdList: 4416
Advantage: 58

Phygene

Tel: 18059081430
Email: 2070812664@qq.com
Country: China
ProdList: 1232
Advantage: 58

Hangzhou Beiputai Biopharmaceutical Co., Ltd

Tel: 0571-85350119 15888826472
Email: bptsales@163.com
Country: China
ProdList: 3834
Advantage: 58

Baoji Didu Pharmaceutical and Chemical Co., Ltd

Tel: 029-029-81148929 17791530722
Email: 1049@dideu.com
Country: China
ProdList: 10011
Advantage: 58

ABRPharm

Tel: 021-52230280 18717909882
Email: fkuebdpe@163.com
Country: China
ProdList: 339
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Enzo Biochem Inc

Tel: Enzo Biochem Inc. 13797054060
Email: Enzoname@qq.com
Country: China
ProdList: 6174
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
Advantage: 58

Hubei Molcoo Biotechnology Co., Ltd

Tel: 17320513646
Email: anna@molcoo.com
Country: China
ProdList: 3256
Advantage: 58

Cohesion Biosciences

Tel: 0512-67583809
Email: sales@cohesionbio.com
Country: China
ProdList: 6282
Advantage: 58

Hangzhou ALLPEPTIDE Biotechnology Co., Ltd.

Tel: 17342063383
Email: sales@allpeptide.com
Country: China
ProdList: 5320
Advantage: 58

LEON (NANJING) BIOTECHNOLOGY CO., LTD.

Tel: +8615051830413
Email: sales.njleonbiotech@gmail.com
Country: China
ProdList: 5482
Advantage: 58

Moxin Chemicals

Tel: +86-17320513646 +8617320513646
Email: anna@molcoo.com
Country: China
ProdList: 10000
Advantage: 58

Forest chemical technology

Tel: +85295407470
Email: grant@forestchem.freeqiye.com
Country: China
ProdList: 752
Advantage: 58

Changsha MOL Changes Biotechnology Co., Ltd.

Tel: +8619375158599
Email: info@molchanges.com
Country: China
ProdList: 5218
Advantage: 58

Shenzhen Nexconn Pharmatechs Ltd

Tel: +86-755-89396905 +86-15013857715
Email: admin@nexconn.com
Country: China
ProdList: 10405
Advantage: 58

Chengdu Youngshe Chemical Co., Ltd.

Tel: +8618108235634
Email: Cecilia@youngshechem.com
Country: China
ProdList: 2345
Advantage: 58

Guangzhou Yiran Biotechnology Co., Ltd.

Tel: 15571990006
Country: CHINA
ProdList: 141
Advantage: 58

Guangzhou Jinling Biotechnology Co., Ltd.

Tel: 15017560539
Country: CHINA
ProdList: 142
Advantage: 58

136795-05-6, H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OHRelated Search:

LYS(BIOTIN)-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH ISOTOCIN [SER2]-NEUROMEDIN C H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-HIS-GLU-VAL-LYS-ASN-OH (Ser8)-GLP-1 (7-36) amide (human, bovine, guinea pig, mouse, rat) PROTEIN KINASE C (19-31) H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH H-ASN-VAL-OH ASN-TYR-PRO-LEU-GLU-LEU-TYR-GLU-ARG-VAL-ARG-THR-GLY-CYS H-THR-THR-TYR-ALA-ASP-PHE-ILE-ALA-SER-GLY-ARG-THR-GLY-ARG-ARG-ASN-ALA-ILE-NH2

[SER 25]-PROTEIN KINASE C FRAGMENT 19-31

PROTEIN KINASE C [SER-25] (19-31)

RFARKGSLRQKNV

H-ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL-OH

ARG-PHE-ALA-ARG-LYS-GLY-SER-LEU-ARG-GLN-LYS-ASN-VAL

[SER25]-PKC (19-31)

[SER25]-PROTEIN KINASE C (19-31)

L-Valine, L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysylglycyl-L-seryl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparaginyl-

7:PN:JP2006076967 SEQID:7 unclaimed protein

Protein Kinase C Fragment [Ser25] Protein Kinase C(19-31)

136795-05-6

C67H118N26O17

Serine/Threonine Kinase Substrates

Protein Kinase C (PKC)

Kinase/Phosphatase Biology

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Neuroscience

Enzyme Substrates

Protein Kinase C (PKC)Peptides for Cell Biology

Protein Kinase CSerine/Threonine Kinase Biology

Protein Kinase Related Peptides

Protein Kinase Substrates

Serine/Threonine Kinase Substrates

Substrates by Enzyme

peptide