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cyclo (Arg-Gly-Asp-d-Phe-Glu)

Product Name
cyclo (Arg-Gly-Asp-d-Phe-Glu)
CAS No.
756500-22-8
Chemical Name
cyclo (Arg-Gly-Asp-d-Phe-Glu)
Synonyms
cyclo(RGD-DPhe-E);cyclo (Arg-Gly-Asp-d-Phe-Glu);Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-α-glutamyl)
CBNumber
CB12594926
Molecular Formula
C26H36N8O9
Formula Weight
604.62
MOL File
756500-22-8.mol
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cyclo (Arg-Gly-Asp-d-Phe-Glu) Property

Density 
1.54±0.1 g/cm3(Predicted)
pka
4.01±0.10(Predicted)
form 
Solid
color 
White to off-white
Sequence
Cyclo(Arg-Gly-Asp-{d-Phe}-Glu)
InChIKey
LHYAAFPJZDQDLU-WHSWRCCXNA-N
SMILES
C(C1C=CC=CC=1)[C@H]1NC([C@@H](NC(CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(=O)O)NC1=O)=O)CC(=O)O)=O |&1:7,10,17,28,r|
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Hazard and Precautionary Statements (GHS)

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cyclo (Arg-Gly-Asp-d-Phe-Glu) Chemical Properties,Usage,Production

Uses

Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) (c(RGDfE)) is a cyclic RGD peptide that serves as a conjugated multifunctional nanodrug delivery system to target Gemcitabine to pancreatic cancer cells. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) can be used in cancer research[1].

References

[1] Sun J , et al. A c(RGDfE) conjugated multi-functional nanomedicine delivery system for targeted pancreatic cancer therapy. J Mater Chem B. 2015 Feb 14;3(6):1049-1058. DOI:10.1039/c4tb01402b

cyclo (Arg-Gly-Asp-d-Phe-Glu) Preparation Products And Raw materials

Raw materials

Preparation Products

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cyclo (Arg-Gly-Asp-d-Phe-Glu) Suppliers

Shanghai HongTide Biotechnology Co.,Ltd.
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15318089928
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Shanghai Chaolan Chemical Technology Center
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756500-22-8, cyclo (Arg-Gly-Asp-d-Phe-Glu)Related Search:


  • cyclo (Arg-Gly-Asp-d-Phe-Glu)
  • Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-α-glutamyl)
  • cyclo(RGD-DPhe-E)
  • 756500-22-8