ChemicalBook > CAS DataBase List > cyclo (Arg-Gly-Asp-d-Phe-Glu)
cyclo (Arg-Gly-Asp-d-Phe-Glu)
- Product Name
- cyclo (Arg-Gly-Asp-d-Phe-Glu)
- CAS No.
- 756500-22-8
- Chemical Name
- cyclo (Arg-Gly-Asp-d-Phe-Glu)
- Synonyms
- cyclo(RGD-DPhe-E);cyclo (Arg-Gly-Asp-d-Phe-Glu);Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-α-glutamyl)
- CBNumber
- CB12594926
- Molecular Formula
- C26H36N8O9
- Formula Weight
- 604.62
- MOL File
- 756500-22-8.mol
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cyclo (Arg-Gly-Asp-d-Phe-Glu) Property
- Density
- 1.54±0.1 g/cm3(Predicted)
- pka
- 4.01±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- Sequence
- Cyclo(Arg-Gly-Asp-{d-Phe}-Glu)
- InChIKey
- LHYAAFPJZDQDLU-WHSWRCCXNA-N
- SMILES
- C(C1C=CC=CC=1)[C@H]1NC([C@@H](NC(CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(=O)O)NC1=O)=O)CC(=O)O)=O |&1:7,10,17,28,r|
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cyclo (Arg-Gly-Asp-d-Phe-Glu) Chemical Properties,Usage,Production
Uses
Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) (c(RGDfE)) is a cyclic RGD peptide that serves as a conjugated multifunctional nanodrug delivery system to target Gemcitabine to pancreatic cancer cells. Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) can be used in cancer research[1].
References
[1] Sun J , et al. A c(RGDfE) conjugated multi-functional nanomedicine delivery system for targeted pancreatic cancer therapy. J Mater Chem B. 2015 Feb 14;3(6):1049-1058. DOI:10.1039/c4tb01402b
cyclo (Arg-Gly-Asp-d-Phe-Glu) Preparation Products And Raw materials
Raw materials
Preparation Products
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