c(phg-isoDGR-(NMe)k)

Product Name: c(phg-isoDGR-(NMe)k)
CAS No.: 1844830-65-4
Chemical Name: c(phg-isoDGR-(NMe)k)
Synonyms: c(phg-isoDGR-(NMe)k);Cyclo(Arg-NMe-DLys-DPhg-β-Asp-Gly);c(phgisoDGR(NMe)k),c(phg isoDGR (NMe)k);Cyclo[L-arginyl-N2-methyl-D-lysyl-(2R)-2-phenylglycyl-L-β-aspartylglycyl]
CBNumber: CB95474896
Molecular Formula: C27H41N9O7
Formula Weight: 603.68
MOL File: 1844830-65-4.mol

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c(phg-isoDGR-(NMe)k) Property

Density: 1.45±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 2.98±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0040557
Product name: c(phg-isoDGR-(NMe)k)
Packaging: 1mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0040557
Product name: c(phg-isoDGR-(NMe)k)
Packaging: 5mg
Price: $980
Updated: 2021/12/16

ChemScene

Product number: CS-0040557
Product name: c(phg-isoDGR-(NMe)k)
Packaging: 10mg
Price: $1500
Updated: 2021/12/16

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c(phg-isoDGR-(NMe)k) Chemical Properties,Usage,Production

Uses

c(phg-isoDGR-(NMe)k) is a selective and potent α5β1-integrin ligand with an IC50 of 2.9 nM[1].

in vivo

c(phg-isoDGR-(NMe)k) is trimerized with the chelator TRAP and used as a positron-emission tomography tracer for monitoring α5β1 integrin expression in a M21 mouse xenograft^[1].

References

[1] Kapp TG, et al. N-Methylation of isoDGR Peptides: Discovery of a Selective α5β1-Integrin Ligand as a Potent Tumor Imaging Agent. J Med Chem. 2018 Mar 22;61(6):2490-2499. DOI:10.1021/acs.jmedchem.7b01752

c(phg-isoDGR-(NMe)k) Preparation Products And Raw materials

Raw materials

Preparation Products

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c(phg-isoDGR-(NMe)k) Suppliers

China 24 United States 2 Global 26

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1844830-65-4, c(phg-isoDGR-(NMe)k)Related Search:

cyclo (Arg-Gly-Asp-d-Phe-Glu)

c(phg-isoDGR-(NMe)k)

Cyclo[L-arginyl-N2-methyl-D-lysyl-(2R)-2-phenylglycyl-L-β-aspartylglycyl]

Cyclo(Arg-NMe-DLys-DPhg-β-Asp-Gly)

c(phgisoDGR(NMe)k),c(phg isoDGR (NMe)k)

1844830-65-4