4-chloro-7-Methoxyquinoline-6-carboxaMide
- Product Name
- 4-chloro-7-Methoxyquinoline-6-carboxaMide
- CAS No.
- 417721-36-9
- Chemical Name
- 4-chloro-7-Methoxyquinoline-6-carboxaMide
- Synonyms
- lenvaint-E;synthesis-024;synthesis-1-014;ine-6-carboxamide;oro-7-methoxyquinoL;Lenvatinib Impurity b;Lenvatinib Impurity 50;Lenvatinib Impurity LFS-B;4-chloro-7-Methoxy-6-QuinolinecarboxaMide;4-chloro-7-Methoxyquinoline-6-carboxaMide
- CBNumber
- CB12596687
- Molecular Formula
- C11H9ClN2O2
- Formula Weight
- 236.65
- MOL File
- 417721-36-9.mol
4-chloro-7-Methoxyquinoline-6-carboxaMide Property
- Melting point:
- >205°C (dec.)
- Boiling point:
- 426.7±45.0 °C(Predicted)
- Density
- 1.380±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 15.28±0.30(Predicted)
- form
- Solid
- color
- Off-White to Light Beige
- InChI
- InChI=1S/C11H9ClN2O2/c1-16-10-5-9-6(4-7(10)11(13)15)8(12)2-3-14-9/h2-5H,1H3,(H2,13,15)
- InChIKey
- ZBTVNIDMGKZSGC-UHFFFAOYSA-N
- SMILES
- N1C2C(=CC(C(N)=O)=C(OC)C=2)C(Cl)=CC=1
- CAS DataBase Reference
- 417721-36-9
Safety
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C369515
- Product name
- 4-Chloro-7-methoxy-6-quinolinecarboxamide
- Packaging
- 1g
- Price
- $85
- Updated
- 2021/12/16
- Product number
- FC158634
- Product name
- 4-Chloro-7-methoxyquinoline-6-carboxamide
- Packaging
- 2g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- FC158634
- Product name
- 4-Chloro-7-methoxyquinoline-6-carboxamide
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR53151
- Product name
- 4-Chloro-7-methoxyquinoline-6-carboxamide
- Purity
- 97%
- Packaging
- 5g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- 4H48-5-C6
- Product name
- 4-Chloro-7-methoxyquinoline-6-carboxamide
- Purity
- 97%
- Packaging
- 5G
- Price
- $160
- Updated
- 2021/12/16
4-chloro-7-Methoxyquinoline-6-carboxaMide Chemical Properties,Usage,Production
Description
4-chloro-7-Methoxyquinoline-6-carboxaMide is a pharmaceutical intermediate compound used in the preparation of Lenvatinib, an oral multi-receptor tyrosine kinase inhibitor approved by the FDA for the treatment of radioiodine-refractory differentiated thyroid cancer (DTC), unresectable (DTC), unresectable hepatocellular carcinoma (HCC), and advanced renal cell carcinoma (RCC).
Chemical Properties
light yellow powder
Uses
Pharmaceutical Intermediates. 4-chloro-7-Methoxyquinoline-6-carboxaMide is used as an intermediate for synthesizing Lenvatinibis.
4-chloro-7-Methoxyquinoline-6-carboxaMide Preparation Products And Raw materials
Raw materials
Preparation Products
4-chloro-7-Methoxyquinoline-6-carboxaMide Suppliers
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View Lastest Price from 4-chloro-7-Methoxyquinoline-6-carboxaMide manufacturers
- Product
- 4-chloro-7-Methoxyquinoline-6-carboxaMide 417721-36-9
- Price
- US $1.00-0.50/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2023-12-11
- Product
- 4-chloro-7-methoxyquinoline-6-carboxamide 417721-36-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-19
- Product
- 4-chloro-7-Methoxyquinoline-6-carboxaMide 417721-36-9
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 99%
- Supply Ability
- 200T
- Release date
- 2023-03-10