Polygalacin D

Uses

Product Name: Polygalacin D
CAS No.: 66663-91-0
Chemical Name: Polygalacin D
Synonyms: Onjisaponin D;Polygalacin D;Polygalacin D2;Olean-12-en-28-oic acid, 3-(β-D-glucopyranosyloxy)-2,16,23-trihydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,4β,16α)-;(2S,3R,4S,5S)-3-(((2S,3R,4S,5R,6S)-5-(((2S,3R,4S,5R)-4-(((2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-3,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxytetrahydro-2H-pyran-2-yl (4aR,5R,6aS,6bR,8aR,9S,10R,11S,12aR,12bR,14bS)-5,11-dihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate
CBNumber: CB12614224
Molecular Formula: C57H92O27
Formula Weight: 1209.34
MOL File: 66663-91-0.mol

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Polygalacin D Property

Density: 1.54±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.: 4°C, protect from light
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 12.76±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 300806
Product name: Polygalacin D
Packaging: 10mg
Price: $632
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259443
Product name: Polygalacin D
Purity: 98%
Packaging: 5mg
Price: $433.5
Updated: 2021/12/16

ChemScene

Product number: CS-0032282
Product name: PolygalacinD
Purity: 99.30%
Packaging: 5mg
Price: $457
Updated: 2021/12/16

ChemScene

Product number: CS-0032282
Product name: PolygalacinD
Purity: 99.30%
Packaging: 1mg
Price: $152
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259443
Product name: Polygalacin D
Purity: 98%
Packaging: 10mg
Price: $591.6
Updated: 2021/12/16

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Polygalacin D Chemical Properties,Usage,Production

Uses

It promotes cognitive function, reduces myocardial damage, and has antitussive and expectorant effects. It is used for content determination/identification/pharmacological experiments, etc.

Chemical Properties

White needle crystal. Soluble in water, ethanol, methanol and other solvents, insoluble in petroleum ether, chloroform, ethyl acetate.

Definition

ChEBI: Polygalacin D is a triterpenoid saponin. It has a role as a metabolite.

Biological Activity

Polygalacin D (PGD) is a bioactive compound with anticancer and antiproliferative properties isolated from Platycodon grandiflorum. It inhibits the expression of the IAP protein family, including survivin, cIAP-1 and cIAP-2 proteins, and blocks the PI3K/Akt pathway by inhibiting GSK3β, Akt phosphorylation and PI3K expression. It induces apoptosis through the PI3K/Akt pathway.

target

NOS | COX | PGE | NO | NF-kB

Polygalacin D Preparation Products And Raw materials

Raw materials

Preparation Products

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Polygalacin D Suppliers

China 90 United States 6 Global 96

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

ALB Technology Limited

Tel: 702-983-3769
Fax: 702-983-3769
Email: sales@albtechnology.com
Country: United States
ProdList: 2993
Advantage: 55

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 6905
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Grice Rand (Tianjin) Pharmaceutical Co., Ltd.

Tel: 022-83705301 13752403750
Fax: 022-83705301
Email: 2966024760@qq.com
Country: China
ProdList: 873
Advantage: 55

Shanghai ChengShao Biological Technology Co., Ltd.

Tel: 021-61847300 13341622919
Fax: 021-61847300
Email: shcss01@163.com
Country: China
ProdList: 4808
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

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View Lastest Price from Polygalacin D manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Polygalacin D 66663-91-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-28

Shanghai Standard Technology Co., Ltd.

Product: Polygalacin D 66663-91-0
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-03

Career Henan Chemical Co

Product: Polygalacin D 66663-91-0
Price: US $16.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg, 10kg, 50kg
Release date: 2020-03-09

66663-91-0, Polygalacin DRelated Search:

Polygalasaponin XXXI Sinegin 3 Tenuifoliside C Tenuifoliside B Onjisaponin Z Onjisaponin O Polygalaxanthone XI Tenuifoliose J a-D-Glucopyranoside,3-O-benzoyl-1-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-b-D-fructofuranosyl O-b-D-glucopyranosyl-(1(R)2)-O-[O-b-D-glucopyranosyl-(1(R)3)-4,6-di-O-acetyl-b-D-glucopyranosyl-(1(R)3)]-, 6-acetate4-[(2E)-3-(4-hydroxyphenyl)-2-propenoate] (9CI) Tenuifoliside A (3-sinapoyl)fructofuranosyl-(6-sinapoyl)glucopyranoside Arillanin A Tenuifoliose A polygalic acid 3-O-Feruloylsucrose Bernardioside A sibiricaxanthone A senegin II

Polygalacin D

Onjisaponin D

Olean-12-en-28-oic acid, 3-(β-D-glucopyranosyloxy)-2,16,23-trihydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,4β,16α)-

Polygalacin D2

(2S,3R,4S,5S)-3-(((2S,3R,4S,5R,6S)-5-(((2S,3R,4S,5R)-4-(((2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-3,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxytetrahydro-2H-pyran-2-yl (4aR,5R,6aS,6bR,8aR,9S,10R,11S,12aR,12bR,14bS)-5,11-dihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate

66663-91-0

C57H92O27