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Polygalacin D

Product Name
Polygalacin D
CAS No.
66663-91-0
Chemical Name
Polygalacin D
Synonyms
Onjisaponin D;Polygalacin D;Polygalacin D2;Olean-12-en-28-oic acid, 3-(β-D-glucopyranosyloxy)-2,16,23-trihydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,4β,16α)-
CBNumber
CB12614224
Molecular Formula
C57H92O27
Formula Weight
1209.34
MOL File
66663-91-0.mol
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Polygalacin D Property

Density 
1.54±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
4°C, protect from light
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
12.76±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
300806
Product name
Polygalacin D
Packaging
10mg
Price
$632
Updated
2021/12/16
Biorbyt Ltd
Product number
orb259443
Product name
Polygalacin D
Purity
98%
Packaging
5mg
Price
$433.5
Updated
2021/12/16
ChemScene
Product number
CS-0032282
Product name
PolygalacinD
Purity
99.30%
Packaging
5mg
Price
$457
Updated
2021/12/16
ChemScene
Product number
CS-0032282
Product name
PolygalacinD
Purity
99.30%
Packaging
1mg
Price
$152
Updated
2021/12/16
Biorbyt Ltd
Product number
orb259443
Product name
Polygalacin D
Purity
98%
Packaging
10mg
Price
$591.6
Updated
2021/12/16
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Polygalacin D Chemical Properties,Usage,Production

Chemical Properties

White needle crystal. Soluble in water, ethanol, methanol and other solvents, insoluble in petroleum ether, chloroform, ethyl acetate.

Definition

ChEBI: Polygalacin D is a triterpenoid saponin. It has a role as a metabolite.

Biological Activity

Polygalacin D (PGD) is a bioactive compound with anticancer and antiproliferative properties isolated from Platycodon grandiflorum. It inhibits the expression of the IAP protein family, including survivin, cIAP-1 and cIAP-2 proteins, and blocks the PI3K/Akt pathway by inhibiting GSK3β, Akt phosphorylation and PI3K expression. It induces apoptosis through the PI3K/Akt pathway.

target

NOS | COX | PGE | NO | NF-kB

Polygalacin D Preparation Products And Raw materials

Raw materials

Preparation Products

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Polygalacin D Suppliers

Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
ALB Technology Limited
Tel
702-983-3769
Fax
702-983-3769
Email
sales@albtechnology.com
Country
United States
ProdList
2993
Advantage
55
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7057
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Shanghai ChengShao Biological Technology Co., Ltd.
Tel
021-61847300 13341622919
Fax
021-61847300
Email
shcss01@163.com
Country
China
ProdList
4808
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Shanghai Yihe Biological Technology Co., Ltd.
Tel
17721395025
Fax
021-68882955
Email
2423903095@qq.com
Country
China
ProdList
4066
Advantage
58
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View Lastest Price from Polygalacin D manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Polygalacin D 66663-91-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-28
Shanghai Standard Technology Co., Ltd.
Product
Polygalacin D 66663-91-0
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-03
Career Henan Chemical Co
Product
Polygalacin D 66663-91-0
Price
US $16.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg, 10kg, 50kg
Release date
2020-03-09